Zobrazeno 1 - 10
of 205
pro vyhledávání: '"John, Cavanagh"'
Clinton rode into office on the promise of'change.'It was a safe, content- free slogan. After all, in recent years, the most radical proposals for change have come not from the Democrats but from the Republican right.'Change'could mean the further do
Autor:
Tonya N. Zeczycki, Morgan E. Milton, David Jung, Richele J. Thompson, Felicia E. Jaimes, Alexander D. Hondros, Samantha Palethorpe, Christian Melander, John Cavanagh
Publikováno v:
Biochemistry. 61:2948-2960
Multidrug-resistant bacteria cause immense public health concerns as once effective antibiotics no longer work against even common infections. Concomitantly, there has been a decline in the discovery of new antibiotics, and the current global clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb181f7aa4bfce5636d45e923686c102
https://doi.org/10.1021/acs.biochem.2c00560
https://doi.org/10.1021/acs.biochem.2c00560
Protein NMR Spectroscopy, Second Edition combines a comprehensive theoretical treatment of NMR spectroscopy with an extensive exposition of the experimental techniques applicable to proteins and other biological macromolecules in solution. Beginning
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Response regulators are a critical part of the two-component system of gene expression regulation in bacteria, transferring a signal from a sensor kinase into DNA binding activity resulting in alteration of gene expression. In this study, we investig
Externí odkaz:
https://doaj.org/article/ebf95fc253f541dca69cd923431e1c6c
Autor:
Morgan E. Milton, Bradley M. Minrovic, Danni L. Harris, Brian Kang, David Jung, Caleb P. Lewis, Richele J. Thompson, Roberta J. Melander, Daina Zeng, Christian Melander, John Cavanagh
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
2-aminoimidazole (2-AI) compounds inhibit the formation of bacterial biofilms, disperse preformed biofilms, and re-sensitize multidrug resistant bacteria to antibiotics. 2-AIs have previously been shown to interact with bacterial response regulators,
Externí odkaz:
https://doaj.org/article/082ce43dccd94bc0a0d952be55b3fb04
Publikováno v:
J Biochem
Acinetobacter baumannii is an insidious emerging nosocomial pathogen that has developed resistance to all available antimicrobials, including the last resort antibiotic, colistin. Colistin resistance often occurs due to mutations in the PmrAB two-com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7056cfd3050c651bc9bb51b828530bf
https://doi.org/10.1093/jb/mvab102
https://doi.org/10.1093/jb/mvab102
Autor:
Morgan E. Milton, John Cavanagh
Publikováno v:
Journal of molecular biology. 435(3)
Bacterial biofilms are notorious for their ability to protect bacteria from environmental challenges, most importantly the action of antibiotics. Bacillus subtilis is an extensively studied model organism used to understand the process of biofilm for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ca542e27a278215971c649daeab834
https://pubmed.ncbi.nlm.nih.gov/36535428
https://pubmed.ncbi.nlm.nih.gov/36535428
Autor:
Paul G. Wahome, Kevin R. Beauchesne, Anna C. Pedone, John Cavanagh, Christian Melander, Paul Zimba, Peter D. R. Moeller
Publikováno v:
Marine Drugs, Vol 13, Iss 1, Pp 65-75 (2014)
Aquatic microbes produce diverse secondary metabolites with interesting biological activities. Cytotoxic metabolites have the potential to become lead compounds or drugs for cancer treatment. Many cytotoxic compounds, however, show undesirable toxici
Externí odkaz:
https://doaj.org/article/9530bf9c56b448d49544ab96070b5207
Autor:
Morgan E. Milton, Michael T. Santoro, Benjamin G. Bobay, Katherine H. Myers, Daniel B. Kearns, John Cavanagh, Sean D. Stowe, Andrew L. Olson, Richele J. Thompson, Erik A. Feldmann, G. Logan Draughn
Publikováno v:
J Mol Biol
Bacteria have developed numerous protection strategies to ensure survival in harsh environments, with perhaps the most robust method being the formation of a protective biofilm. In biofilms, bacterial cells are embedded within a matrix that is compos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32ca89d60e7f6652ade3872b4d4903c
https://doi.org/10.1016/j.jmb.2019.08.019
https://doi.org/10.1016/j.jmb.2019.08.019
Acinetobacter baumannii Regulates Its Stress Responses via the BfmRS Two-Component Regulatory System
Autor:
Samantha Palethorpe, John M. Farrow, Greg Wells, Morgan E. Milton, Luis A. Actis, John Cavanagh, Everett C. Pesci
Publikováno v:
J Bacteriol
Acinetobacter baumannii is a common nosocomial pathogen that utilizes numerous mechanisms to aid its survival in both the environment and the host. Coordination of such mechanisms requires an intricate regulatory network. We report here that A. bauma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04976c91800b273b7bcbbccb79740414
https://pubmed.ncbi.nlm.nih.gov/34871031
https://pubmed.ncbi.nlm.nih.gov/34871031