Zobrazeno 1 - 10
of 880
pro vyhledávání: '"John, Butler"'
Autor:
John, Butler Rory Niels
In this dissertation I have investigated roles of the 19S proteasome regulatory particle spanning all three types of cell division processes, including meiosis I, meiosis II and mitosis. Utilizing the conditional phenotype of an epitope tagged allele
Autor:
Benjamin Wilk, Haris Smailovic, Rebecca Sullivan, Erik R. Sistermans, John Butler, Hannah Jago, Michael Kovacs, Gerald Wisenberg, Jonathan D. Thiessen, Frank S. Prato
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background After myocardial infarction, fibrosis and an ongoing dysregulated inflammatory response have been shown to lead to adverse cardiac remodeling. FDG PET is an imaging modality sensitive to inflammation as long as suppression protoco
Externí odkaz:
https://doaj.org/article/2d4ef712cec94d168475b9a1309e76f5
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The streptococcal enzymes IdeS and EndoS cleave IgG antibodies with exquisite substrate specificity, which has enabled their development as clinical and biotechnological tools. Here, the authors present crystal structures of both enzymes in complex w
Externí odkaz:
https://doaj.org/article/a78e2cdfa2034e009850d8a61d09e31e
Autor:
Faiza Gaba, Oleg Blyuss, Dhivya Chandrasekaran, Nicolò Bizzarri, Basel Refky, Desmond Barton, Thomas Ind, Marielle Nobbenhuis, John Butler, Owen Heath, Arjun Jeyarajah, Elly Brockbank, Alexandra Lawrence, Ranjit Manchanda, James Dilley, Saurabh Phadnis, on behalf of the GO SOAR Collaborative
Publikováno v:
Diagnostics, Vol 13, Iss 22, p 3484 (2023)
For women achieving clinical remission after the completion of initial treatment for epithelial ovarian cancer, 80% with advanced-stage disease will develop recurrence. However, the standard treatment of women with recurrent platinum-sensitive diseas
Externí odkaz:
https://doaj.org/article/c8b485575fd84e23ad1a8042bd70eaea
Autor:
Ivan Cokic, Shing Fai Chan, Xingmin Guan, Anand R. Nair, Hsin-Jung Yang, Ting Liu, Yinyin Chen, Diego Hernando, Jane Sykes, Richard Tang, John Butler, Alice Dohnalkova, Libor Kovarik, Robert Finney, Avinash Kali, Behzad Sharif, Louis S. Bouchard, Rajesh Gupta, Mayil Singaram Krishnam, Keyur Vora, Balaji Tamarappoo, Andrew G. Howarth, Andreas Kumar, Joseph Francis, Scott B. Reeder, John C. Wood, Frank S. Prato, Rohan Dharmakumar
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
It is unclear why hemorrhagic myocardial infarctions (hMI) are destined for adverse outcomes. Here, the authors show that hMI drives fatty degeneration of infarct territories and contributes to adverse remodeling of the heart, which can be mitigated
Externí odkaz:
https://doaj.org/article/3fcbb124b97648aaa977eecd97230304
Autor:
Rhia Kaur Saggu, Phillip Barlow, John Butler, Sadaf Ghaem-Maghami, Cathy Hughes, Pernilla Lagergren, Alison H. McGregor, Clare Shaw, Mary Wells
Publikováno v:
BMC Women's Health, Vol 22, Iss 1, Pp 1-35 (2022)
Abstract Background There is increasing recognition that prehabilitation is important as a means of preparing patients physically and psychologically for cancer treatment. However, little is understood about the role and optimal nature of prehabilita
Externí odkaz:
https://doaj.org/article/4f4036ba8b2d4b4f8991583ec5470789
Autor:
Oi-Wai Chau, Omar El-Sherif, Matthew Mouawad, Jane M Sykes, John Butler, Heather Biernaski, Robert deKemp, Jennifer Renaud, Gerald Wisenberg, Frank S Prato, Stewart Gaede
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291854 (2023)
BackgroundLeft-sided breast cancer patients receiving adjuvant radiotherapy are at risk for coronary artery disease, and/or radiation mediated effects on the microvasculature. Previously our laboratory demonstrated in canines with hybrid 18FDG/PET a
Externí odkaz:
https://doaj.org/article/2135040d4b5b42e8994c5fc60899ca3a
Autor:
John Butler, Melissa Taylor
Publikováno v:
Forensic Science International: Synergy, Vol 6, Iss , Pp 100405- (2023)
Externí odkaz:
https://doaj.org/article/daba25127c294d41ac146287bd9dd4e7
Autor:
Charlotte Lynch BSc, MSc, Samantha Harrison BSc, MSc, John Butler MRCOG, MBBS, BSc, David R. Baldwin MA, DM, FRCPsych, FRSA, FHEA, Paul Dawkins MB ChB, MRCP, CCT Resp Med and Gen (Int) Med, FRCP 2012, FRACP, Joris van der Horst MD, FRCP, Erik Jakobsen MD, MPM, Jonathan McAleese MD, Annette McWilliams MBBS, Karen Redmond MB BCh NUI, Anand Swaminath MD, MSc, FRCPC, Christian J. Finley MD, MPH
Publikováno v:
Cancer Control, Vol 29 (2022)
Background Research from the International Cancer Benchmarking Partnership (ICBP) demonstrates that international variation in lung cancer survival persists, particularly within early stage disease. There is a lack of international consensus on the c
Externí odkaz:
https://doaj.org/article/8e456908d8844a9582a9f7189fcaf356
Autor:
Xingmin Guan, Yinyin Chen, Hsin-Jung Yang, Xinheng Zhang, Daoyuan Ren, Jane Sykes, John Butler, Hui Han, Mengsu Zeng, Frank S. Prato, Rohan Dharmakumar
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-15 (2021)
Abstract Background Intramyocardial hemorrhage (IMH) within myocardial infarction (MI) is associated with major adverse cardiovascular events. Bright-blood T2*-based cardiovascular magnetic resonance (CMR) has emerged as the reference standard for no
Externí odkaz:
https://doaj.org/article/b3d7bd9832ae4edd80c35dcfb78cd47f