Zobrazeno 1 - 10
of 34
pro vyhledávání: '"John, Benktander"'
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1741-1751 (2022)
ABSTRACTCarbohydrates can both protect against infection and act as targets promoting infection. Mucins are major components of the slimy mucus layer covering the fish epithelia. Mucins can act as decoys for intimate pathogen interaction with the hos
Externí odkaz:
https://doaj.org/article/d0b4b50cfb394824a9d6e89f776d0e8b
Autor:
Gurdeep Chahal, Macarena P. Quintana-Hayashi, Meztlli O. Gaytán, John Benktander, Medea Padra, Samantha J. King, Sara K. Linden
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Streptococcus oralis is an oral commensal and opportunistic pathogen that can enter the bloodstream and cause bacteremia and infective endocarditis. Here, we investigated the mechanisms of S. oralis binding to oral mucins using clinical isolates, iso
Externí odkaz:
https://doaj.org/article/536cb2fe501444db88bf721f2f0b3312
Autor:
Médea Padra, Barbara Adamczyk, John Benktander, Bram Flahou, Emma C. Skoog, János Tamás Padra, Annemieke Smet, Chunsheng Jin, Richard Ducatelle, Tore Samuelsson, Freddy Haesebrouck, Niclas G. Karlsson, Susann Teneberg, Sara K. Lindén
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 898-918 (2018)
Helicobacter suis colonizes the stomach of most pigs and is the most prevalent non-Helicobacter pylori Helicobacter species found in the human stomach. In the human host, H. suis contributes to the development of chronic gastritis, peptic ulcer disea
Externí odkaz:
https://doaj.org/article/a2f406ab04414766ae8b972745ac379a
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 738-751 (2018)
Adhesion of Helicobacter pylori to the gastric mucosa is a prerequisite for the pathogenesis of H. pylori related diseases. In this study, we investigated the ganglioside composition of human stomach as the target for attachment mediated by H. pylori
Externí odkaz:
https://doaj.org/article/4c29ae4f8e544af19d1f027867bba2dd
Autor:
János Tamás Padra, Abarna V M Murugan, Kristina Sundell, Henrik Sundh, John Benktander, Sara K Lindén
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215583 (2019)
Disease outbreaks are limiting factors for an ethical and economically sustainable aquaculture industry. The first point of contact between a pathogen and a host occurs in the mucus, which covers the epithelial surfaces of the skin, gills and gastroi
Externí odkaz:
https://doaj.org/article/8a586717fa634b358b64804e7e437fc3
Autor:
John Benktander, János T. Padra, Ben Maynard, George Birchenough, Natasha A. Botwright, Russel McCulloch, James W. Wynne, Sinan Sharba, Kristina Sundell, Henrik Sundh, Sara K. Lindén
Publikováno v:
Microorganisms, Vol 8, Iss 12, p 1871 (2020)
Amoebic gill disease (AGD) causes poor performance and death in salmonids. Mucins are mainly comprised by carbohydrates and are main components of the mucus covering the gill. Since glycans regulate pathogen binding and growth, glycosylation changes
Externí odkaz:
https://doaj.org/article/b26d71c8d6ee4045adb9c6eabd1e8599
Autor:
Kristina A. Thomsson, John Benktander, Macarena P. Quintana-Hayashi, Sinan Sharba, Sara K. Lindén
Publikováno v:
Fishshellfish immunology. 131
Mucins are highly glycosylated proteins that make up the mucus covering internal and external surfaces of fish. Mucin O-glycans regulate pathogen quorum sensing, growth, virulence and attachment to the host. Knowledge on this mucosal defense system c
Autor:
Macarena P. Quintana-Hayashi, Médea Padra, János Tamás Padra, John Benktander, Sara K. Lindén
Publikováno v:
Microorganisms, Vol 6, Iss 2, p 55 (2018)
Gastrointestinal infections cause significant challenges and economic losses in animal husbandry. As pathogens becoming resistant to antibiotics are a growing concern worldwide, alternative strategies to treat infections in farmed animals are necessa
Externí odkaz:
https://doaj.org/article/3affdbd137fe47188614822365075908
Autor:
Sinan Sharba, Henrik Sundh, Kristina Sundell, John Benktander, Licinia Santos, George Birchenough, Sara K. Lindén
Publikováno v:
Fishshellfish immunology. 122
Mucus, whereof the highly glycosylated mucins are a major component, protects the epithelial mucosal surfaces. The aim of this study was to characterize the rainbow trout (Oncorhynchus mykiss) gastrointestinal mucus barrier function, mucin production
Autor:
Médea, Padra, John, Benktander, János T, Padra, Anders, Andersson, Bettina, Brundin, Sara, Tengvall, Karin, Christenson, Ingemar, Qvarfordt, Robert, Gad, Magnus, Paulsson, Nikolaos, Pournaras, Anders, Lindén, Sara K, Lindén
Publikováno v:
American journal of respiratory cell and molecular biology. 65(6)
Chronic obstructive pulmonary disease (COPD) is associated with colonization by bacterial pathogens and repeated airway infections, leading to exacerbations and impaired lung function. The highly glycosylated mucins in the mucus lining the airways ar