Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Johannes Wolf"'
Publikováno v:
Diagnostics, Vol 14, Iss 12, p 1286 (2024)
Reduced lymphocyte counts in peripheral blood are one of the most common observations in acute phases of viral infections. Although many studies have already examined the impact of immune (dys)regulation during SARS-CoV-2 infection, there are still u
Externí odkaz:
https://doaj.org/article/9207b017901a45a38b6360f0f8aa4f93
Autor:
Mandy Schwarze, Daniela Volke, Juan Camilo Rojas Echeverri, Robin Schick, Nicole Lakowa, Thomas Grünewald, Johannes Wolf, Stephan Borte, Markus Scholz, Andor Krizsan, Ralf Hoffmann
Publikováno v:
Biology, Vol 13, Iss 4, p 207 (2024)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. Here, we report the influence of N-glycosylation sites of the RBD
Externí odkaz:
https://doaj.org/article/cbcbb68c75094c2a8742d092a84ad010
Autor:
Ji Luo, Alexandra Brakel, Andor Krizsan, Tobias Ludwig, Marina Mötzing, Daniela Volke, Nicole Lakowa, Thomas Grünewald, Claudia Lehmann, Johannes Wolf, Stephan Borte, Sanja Milkovska-Stamenova, Jörg Gabert, Felix Fingas, Markus Scholz, Ralf Hoffmann
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-10 (2022)
Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered the worldwide coronavirus disease 2019 (COVID-19) pandemic. Serological assays for the detection of SARS-CoV-2 infections are important to understand t
Externí odkaz:
https://doaj.org/article/c482d7c47e974f4aac666d738e04448e
Autor:
Michael Szardenings, Nicolas Delaroque, Karolin Kern, Lisbeth Ramirez-Caballero, Marcus Puder, Eva Ehrentreich-Förster, Joachim Beige, Sebastian Zürner, Georg Popp, Johannes Wolf, Stephan Borte
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1403 (2023)
(1) Background: Coronavirus proteins are quite conserved amongst endemic strains (eCoV) and SARS-CoV-2. We aimed to evaluate whether peptide epitopes might serve as useful diagnostic biomarkers to stratify previous infections and COVID-19. (2) Method
Externí odkaz:
https://doaj.org/article/73394375d55f43839cbe523e161b032a
Autor:
Alexandra Rockstroh, Johannes Wolf, Jasmin Fertey, Sven Kalbitz, Stefanie Schroth, Christoph Lübbert, Sebastian Ulbert, Stephan Borte
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 774-781 (2021)
Monitoring the humoral protective immune response and its durability after SARS-CoV-2 infections is essential for risk assessment of reinfections, the improvement of diagnostic methods and the evaluation of vaccine trials. We have analyzed neutralizi
Externí odkaz:
https://doaj.org/article/5b1af8a3e4cd4d7592ea00c2ba6afa5e
Autor:
Mandy Schwarze, Ji Luo, Alexandra Brakel, Andor Krizsan, Nicole Lakowa, Thomas Grünewald, Claudia Lehmann, Johannes Wolf, Stephan Borte, Sanja Milkovska-Stamenova, Jörg Gabert, Markus Scholz, Ralf Hoffmann
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1515 (2022)
This study investigated the IgG and IgA antibody response against recombinant S1 and receptor binding domains (RBD) of the spike (S-) protein and the membrane (M-) protein using a set of 115 serum samples collected from patients infected with SARS-Co
Externí odkaz:
https://doaj.org/article/c5e9b80dd4e84a17bb0ad48e1e8fe4a1
Autor:
Olaf Nickel, Alexandra Rockstroh, Johannes Wolf, Susann Landgraf, Sven Kalbitz, Nils Kellner, Michael Borte, Corinna Pietsch, Jasmin Fertey, Christoph Lübbert, Sebastian Ulbert, Stephan Borte
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Background The currently used SARS-CoV-2 mRNA vaccines have proven to induce a strong and protective immune response. However, functional relevance of vaccine-generated antibodies and their temporal progression are still poorly understood. Thus, the
Externí odkaz:
https://doaj.org/article/6638f1b755304fc0911b45cefdc5fb6c
Publikováno v:
Vaccines, Vol 10, Iss 3, p 347 (2022)
Immunization for the generation of protective antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged to be highly effective in preventing hospital admission, need for intensive care treatment and high mortality in
Externí odkaz:
https://doaj.org/article/c6d880b121bc419cbef976a3b3546982
Publikováno v:
Advanced Modeling and Simulation in Engineering Sciences, Vol 5, Iss 1, Pp 1-40 (2018)
Abstract The paper presents a robust algorithm, which allows to implicitly describe and track immersed geometries within a background mesh. The background mesh is assumed to be unstructured and discretized by tetrahedrons. The contained geometry is a
Externí odkaz:
https://doaj.org/article/c236665972964632ac0d1cc23f1626bc
Autor:
Johannes Wolf, Edith Willscher, Henry Loeffler-Wirth, Maria Schmidt, Gunter Flemming, Marlen Zurek, Holm H. Uhlig, Norman Händel, Hans Binder
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2551 (2021)
Coeliac disease (CD) is a clinically heterogeneous autoimmune disease with variable presentation and progression triggered by gluten intake. Molecular or genetic factors contribute to disease heterogeneity, but the reasons for different outcomes are
Externí odkaz:
https://doaj.org/article/07647190d81b47f095fdbbc2503ea986