Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Johannes Woitzik"'
Autor:
A. Zdunczyk, L. Schumm, S. O. A. Helgers, M. Nieminen-Kelhä, X. Bai, S. Major, J. P. Dreier, N. Hecht, Johannes Woitzik
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Spreading depolarizations (SDs) occur frequently in patients with malignant hemispheric stroke. In animal-based experiments, SDs have been shown to cause secondary neuronal damage and infarct expansion during the initial period of infarct pr
Externí odkaz:
https://doaj.org/article/26ec4eadedf041c0a187040eaf9347f5
Autor:
Roberto Díaz-Peregrino, Modar Kentar, Carlos Trenado, Renán Sánchez-Porras, Pablo Albiña-Palmarola, Francisco L. Ramírez-Cuapio, Daniel San-Juan, Andreas Unterberg, Johannes Woitzik, Edgar Santos
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
ObjectiveCharacterize the neurophysiological effects of mild hypothermia on stroke and spreading depolarizations (SDs) in gyrencephalic brains.MethodsLeft middle cerebral arteries (MCAs) of six hypothermic and six normothermic pigs were permanently o
Externí odkaz:
https://doaj.org/article/d9a5ada955c54fc9b74dfa0e5177093a
Autor:
Nils Hecht, Daisy Haddad, Leoni Schumm, Nora Dengler, Patrick Dömer, Max Schrammel, Franziska Meinert, Sebastian Major, Coline Lemale, Jens Dreier, Peter Vajkoczy, Johannes Woitzik
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 101966- (2023)
Externí odkaz:
https://doaj.org/article/d8dbbc9eefc34323bbabe5dd0cb808af
Autor:
Franziska Meinert, Coline L. Lemâle, Sebastian Major, Simeon O. A. Helgers, Patrick Dömer, Rik Mencke, Martin N. Bergold, Jens P. Dreier, Nils Hecht, Johannes Woitzik
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
IntroductionWyler-strip electrodes for subdural electrocorticography (ECoG) are the gold standard for continuous bed-side monitoring of pathological cortical network events, such as spreading depolarizations (SD) and electrographic seizures. Recently
Externí odkaz:
https://doaj.org/article/a838d33005aa4f86af4620868532b04a
Autor:
Modar Kentar, Roberto Díaz-Peregrino, Carlos Trenado, Renán Sánchez-Porras, Daniel San-Juan, F. Leonardo Ramírez-Cuapio, Niklas Holzwarth, Lena Maier-Hein, Johannes Woitzik, Edgar Santos
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
AimTo describe the spatial and temporal electrocorticographic (ECoG) changes after middle cerebral artery occlusion (MCAo), including those caused by spreading depolarization (SD) in the pig brain.MethodsThe left middle cerebral arteries (MCAs) were
Externí odkaz:
https://doaj.org/article/2249d378bc12492c987e1afb4f052626
Autor:
José Manuel Valdueza, Jens Peter Dreier, Johannes Woitzik, Christian Dohmen, Oliver Sakowitz, Johannes Platz, Stefanie Leistner-Glaess, Victoria Dorothea Witt
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundOur objective was to observe the course of preexisting migraine following subarachnoid hemorrhage (SAH) in patients with and without craniotomy.MethodsWe designed an exploratory analysis and hypothesis-generating study of prospectively coll
Externí odkaz:
https://doaj.org/article/86917a819bfa43a79e5f291b45ffab53
Autor:
Coline L. Lemale, Janos Lückl, Viktor Horst, Clemens Reiffurth, Sebastian Major, Nils Hecht, Johannes Woitzik, Jens P. Dreier
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Neuronal cytotoxic edema is the morphological correlate of the near-complete neuronal battery breakdown called spreading depolarization, or conversely, spreading depolarization is the electrophysiological correlate of the initial, still reversible ph
Externí odkaz:
https://doaj.org/article/4e7dfd58161c4cd89af934f5a6ea88c0
Autor:
Edgar Santos, Arturo Olivares-Rivera, Sebastian Major, Renán Sánchez-Porras, Lorenz Uhlmann, Kevin Kunzmann, Roland Zerelles, Modar Kentar, Vasilis Kola, Adrian Hernández Aguilera, Mildred Gutierrez Herrera, Coline L. Lemale, Johannes Woitzik, Jed A. Hartings, Oliver W. Sakowitz, Andreas W. Unterberg, Jens P. Dreier
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-14 (2019)
Abstract Objective Spreading depolarizations (SD) are characterized by breakdown of transmembrane ion gradients and excitotoxicity. Experimentally, N-methyl-d-aspartate receptor (NMDAR) antagonists block a majority of SDs. In many hospitals, the NMDA
Externí odkaz:
https://doaj.org/article/9b40430ff25646b0a61030a788c3d720
Autor:
Svetlana Lublinsky, Sebastian Major, Vasilis Kola, Viktor Horst, Edgar Santos, Johannes Platz, Oliver Sakowitz, Michael Scheel, Christian Dohmen, Rudolf Graf, Hartmut Vatter, Stefan Wolf, Peter Vajkoczy, Ilan Shelef, Johannes Woitzik, Peter Martus, Jens P. Dreier, Alon Friedman
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 460-472 (2019)
Background: Disease progression and delayed neurological complications are common after aneurysmal subarachnoid hemorrhage (aSAH). We explored the potential of quantitative blood-brain barrier (BBB) imaging to predict disease progression and neurolog
Externí odkaz:
https://doaj.org/article/0e928f6c9ee2424188429bd6b7650627
Autor:
Denny Milakara, Cristian Grozea, Markus Dahlem, Sebastian Major, Maren K.L. Winkler, Janos Lückl, Michael Scheel, Vasilis Kola, Karl Schoknecht, Svetlana Lublinsky, Alon Friedman, Peter Martus, Jed A. Hartings, Johannes Woitzik, Jens P. Dreier
Publikováno v:
NeuroImage: Clinical, Vol 16, Iss , Pp 524-538 (2017)
In many cerebral grey matter structures including the neocortex, spreading depolarization (SD) is the principal mechanism of the near-complete breakdown of the transcellular ion gradients with abrupt water influx into neurons. Accordingly, SDs are ab
Externí odkaz:
https://doaj.org/article/3a13ecccfe834c32a3446ca0551db717