Smoking-Associated Exposure of Human Primary Bronchial Epithelial Cells to Aldehydes: Impact on Molecular Mechanisms Controlling Mitochondrial Content and Function

Autor: Christy B. M. Tulen, Evert Duistermaat, Johannes W. J. M. Cremers, Walther N. M. Klerx, Paul H. B. Fokkens, Naömi Weibolt, Nico Kloosterboer, Mieke A. Dentener, Eric R. Gremmer, Phyllis J. J. Jessen, Evi J. C. Koene, Lou Maas, Antoon Opperhuizen, Frederik-Jan van Schooten, Yvonne C. M. Staal, Alexander H. V. Remels

Publikováno v: Cells, Vol 11, Iss 21, p 3481 (2022)

Chronic obstructive pulmonary disease (COPD) is a devastating lung disease primarily caused by exposure to cigarette smoke (CS). During the pyrolysis and combustion of tobacco, reactive aldehydes such as acetaldehyde, acrolein, and formaldehyde are f

Externí odkaz: https://doaj.org/article/2858f0d527984676b53f121e83d3e3b9

GC-MS analysis of e-cigarette refill solutions: A comparison of flavoring composition between flavor categories

Autor: Jeroen L. A. Pennings, Johannes W J M Cremers, Frank Bakker, Erna J Z Krüsemann, Sanne Boesveldt, Reinskje Talhout

Publikováno v: Journal of Pharmaceutical and Biomedical Analysis 188 (2020)
Journal of Pharmaceutical and Biomedical Analysis, 188

Objectives: Electronic cigarette refill solutions (e-liquids) are available in various flavor descriptions that can be categorized as fruit, tobacco, and more. Flavors increase sensory appeal, thereby stimulating e-cigarette use, and flavoring ingred

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd0c4ad86e219ff70affdc4c71f615a
http://hdl.handle.net/10029/623882

Sensory analysis of characterising flavours: evaluating tobacco product odours using an expert panel

Autor: Pieter H. Punter, C. de Graaf, Johannes W J M Cremers, Suzanne van de Nobelen, Erna J Z Krüsemann, Sanne Boesveldt, Loes van Tiel, Marlou P. Lasschuijt, Reinskje Talhout, René A. de Wijk

Publikováno v: Tobacco Control
Tobacco Control 28 (2019)
Tobacco Control, 28, 152-160

ObjectivesTobacco flavours are an important regulatory concept in several jurisdictions, for example in the USA, Canada and Europe. The European Tobacco Products Directive 2014/40/EU prohibits cigarettes and roll-your-own tobacco having a characteris

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0b4a0c06ed728414cff11c60853309
https://pubmed.ncbi.nlm.nih.gov/29792305

Short-Term Stability of Biomarkers of Oxidative Stress and Antioxidant Status in Human Serum

Autor: Dale Viezeliene, Johannes W J M Cremers, Jiri Skalicky, Vladimira Muzakova, Piet Beekhof, Eugène H.J.M. Jansen

Publikováno v: ISRN Biomarkers. 2013:1-5

The oxidation and antioxidant status of serum are often determined in serum samples which have been frozen for some time. The oxidative stress process is prone to fast alterations in the sample because of the possible instability of the reactants. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92e214c02b1a48ec2418b606725247b
https://doi.org/10.1155/2013/316528

Quality control data of physiological and immunological biomarkers measured in serum and plasma

Autor: Nicolle Breusing, Ewa Sikora, Alexander Bürkle, Eugène H.J.M. Jansen, Piet Beekhof, Maria Moreno-Villanueva, Miriam Capri, Tilman Grune, Jürgen Bernhard, Birgit Weinberger, Claudio Franceschi, Efstathios S. Gonos, Simone Fiegl, Martijn E.T. Dollé, Johannes W J M Cremers, Olivier Toussaint

Publikováno v: Jansen, E, Beekhof, P, Cremers, J, Weinberger, B, Fiegl, S, Toussaint, O, Bernhard, J, Gonos, E, Capri, M, Franceschi, C, Sikora, E, Moreno-Villanueva, M, Breusing, N, Grune, T, Bürkle, A & Dollé, M E T 2015, ' Quality control data of physiological and immunological biomarkers measured in serum and plasma ', Mechanisms of Ageing and Development, vol. 151, pp. 54-59 . https://doi.org/10.1016/j.mad.2015.06.004
Mechanisms of ageing and development, 151: 54-59

In two work packages of the MARK-AGE project, 37 immunological and physiological biomarkers were measured in 3637 serum, plasma or blood samples in five batches during a period of 4 years.The quality of the serum and plasma samples was very good as j

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041b58fac69a8e804624bd5a14bb278f
http://hdl.handle.net/11585/521366