Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Johannes U. Mayer"'
Autor:
Jona Schinner, Tomas Cunha, Johannes U. Mayer, Stefan Hörster, Peter Kind, Dario Didona, Corinna Keber, Michael Hertl, Thomas Worzfeld, Hazem A. Juratli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWe here thought to dissect the inflammatory signature in lesions of three skin disorders, which show a common adaptive immune response against autoantigens of the skin but are characterized by diverging clinical phenotypes. Pemphigus vulg
Externí odkaz:
https://doaj.org/article/37d5ee7a440a444bbade011147d5dd2b
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Basophils play an important role in the development of type 2 immunity and have been linked to protective immunity against parasites but also inflammatory responses in allergic diseases. While typically classified as degranulating effector cells, dif
Externí odkaz:
https://doaj.org/article/c6493903edfb47bdb22e5725b26764ec
Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
Autor:
Kerry L. Hilligan, Shiau-Choot Tang, Evelyn J. Hyde, Elsa Roussel, Johannes U. Mayer, Jianping Yang, Kirsty A. Wakelin, Alfonso J. Schmidt, Lisa M. Connor, Alan Sher, Andrew S. MacDonald, Franca Ronchese
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Antigen presenting cells induce CD4+ T helper (Th) differentiation upon pathogen encounters. Here the authors use fluorescently-labeled bacteria, helminth and fungi to track and describe the functions of IRF4+ migratory type 2 dendritic cells and mon
Externí odkaz:
https://doaj.org/article/d65f3d80f398424cae180d6d1bb01a61
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The balance of type 1 and type 2 immune responses plays a crucial role in anti-helminth immunity and can either support chronic infection or drive type 2 mediated expulsion of the parasite. Helminth antigens and secreted molecules directly influence
Externí odkaz:
https://doaj.org/article/e7bbfc56d7a743d2892fbf561c37b368
Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon
Autor:
Johannes U. Mayer, Mimoza Demiri, William W. Agace, Andrew S. MacDonald, Marcus Svensson-Frej, Simon W. Milling
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
T helper 2 (Th2) cell responses are essential for immunity against parasites, but how Th2 response is modulated in the gut is still unclear. Here the authors show that distinct dendritic cell subsets distinguishable by CD11b, CD103 and IRF4 function
Externí odkaz:
https://doaj.org/article/3c27826cbd534f9586aaa3ade5f87475
Autor:
Johannes U. Mayer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/3a954102aa7c488da6e8bbf55b81861e
Autor:
Laura Ferrer-Font, Palak Mehta, Phoebe Harmos, Alfonso J Schmidt, Sally Chappell, Kylie M Price, Ian F Hermans, Franca Ronchese, Graham le Gros, Johannes U Mayer
Publikováno v:
eLife, Vol 9 (2020)
Single cell isolation from helminth-infected murine intestines has been notoriously difficult, due to the strong anti-parasite type 2 immune responses that drive mucus production, tissue remodeling and immune cell infiltration. Through the systematic
Externí odkaz:
https://doaj.org/article/24e93b44c4e44e5b843135ff7c8da27d
Autor:
Karmella Naidoo, Aurélie Gestin, Yanyan Li, Ian F. Hermans, Katie Gell, Gavin F. Painter, Andrew J. Marshall, Elizabeth A. Jacobsen, David O’Sullivan, Alfonso J Schmidt, Olivier Gasser, Alissa Cait, Christophe Pellefigues, Katherine Woods, Regan J. Anderson, Johannes U Mayer, Kef K Prasit
Background: Mucosal-associated invariant T (MAIT) cells are unconventional T cells which recognize microbial metabolites presented by the major histocompatibility complex class I-related molecule MR1. Although MAIT cells have been shown to reside in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b876d355c85ce84c5a8acc008659bfba
https://doi.org/10.1111/all.14994
https://doi.org/10.1111/all.14994
Autor:
Kirsty A. Wakelin, Greta R Webb, Frank Brombacher, Lisa M Connor, Alan Sher, Sventja von Daake, David Gallego-Ortega, Luis Munoz-Erazo, Jianping Yang, Franca Ronchese, Sally Chappell, Charles R. Mackay, Johannes U Mayer, Dragana Jankovic, Matthew R. Hepworth, Graham Le Gros, David Eccles, Shiau-Choot Tang, Jodie Chandler, Olivier Lamiable, Kerry L Hilligan, Samuel I Old, Evelyn J Hyde, Rita G. Domingues, Roxane Tussiwand
Publikováno v:
Nature Immunology. 22:1538-1550
The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral environments remain mostly undefined. We show that differentiation of CD11blo migratory DC2s-a DC2 population unique to the dermis-required IL-13 signaling depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a8f10747be6403aa118da0f9d7bdd1d
https://doi.org/10.1038/s41590-021-01067-0
https://doi.org/10.1038/s41590-021-01067-0