Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Johannes Thomsen"'
Autor:
Markus Götz, Anders Barth, Søren S. -R. Bohr, Richard Börner, Jixin Chen, Thorben Cordes, Dorothy A. Erie, Christian Gebhardt, Mélodie C. A. S. Hadzic, George L. Hamilton, Nikos S. Hatzakis, Thorsten Hugel, Lydia Kisley, Don C. Lamb, Carlos de Lannoy, Chelsea Mahn, Dushani Dunukara, Dick de Ridder, Hugo Sanabria, Julia Schimpf, Claus A. M. Seidel, Roland K. O. Sigel, Magnus B. Sletfjerding, Johannes Thomsen, Leonie Vollmar, Simon Wanninger, Keith R. Weninger, Pengning Xu, Sonja Schmid
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/1b1c0a8db83947af9fa8432a08f638ac
Autor:
Markus Götz, Anders Barth, Søren S.-R. Bohr, Richard Börner, Jixin Chen, Thorben Cordes, Dorothy A. Erie, Christian Gebhardt, Mélodie C. A. S. Hadzic, George L. Hamilton, Nikos S. Hatzakis, Thorsten Hugel, Lydia Kisley, Don C. Lamb, Carlos de Lannoy, Chelsea Mahn, Dushani Dunukara, Dick de Ridder, Hugo Sanabria, Julia Schimpf, Claus A. M. Seidel, Roland K. O. Sigel, Magnus Berg Sletfjerding, Johannes Thomsen, Leonie Vollmar, Simon Wanninger, Keith R. Weninger, Pengning Xu, Sonja Schmid
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Single-molecule FRET (smFRET) is a versatile technique to study the dynamics and function of biomolecules since it makes nanoscale movements detectable as fluorescence signals. The powerful ability to infer quantitative kinetic information f
Externí odkaz:
https://doaj.org/article/f3d0063840344222b5c71d7c09bdcf04
Autor:
Simon Bo Jensen, Sara Thodberg, Shaheena Parween, Matias E. Moses, Cecilie C. Hansen, Johannes Thomsen, Magnus B. Sletfjerding, Camilla Knudsen, Rita Del Giudice, Philip M. Lund, Patricia R. Castaño, Yanet G. Bustamante, Maria Natalia Rojas Velazquez, Flemming Steen Jørgensen, Amit V. Pandey, Tomas Laursen, Birger Lindberg Møller, Nikos S. Hatzakis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
P450 oxidoreductase (POR) selectively activates numerous cytochromes P450 (CYP), crucial for metabolism of drugs, steroids and xenobiotics and natural product biosynthesis. Here, the authors identify ligands that bind POR and bias its specificity tow
Externí odkaz:
https://doaj.org/article/ecd3eccafadb4f149283420e2e8e2cea
Autor:
Johannes Thomsen, Magnus Berg Sletfjerding, Simon Bo Jensen, Stefano Stella, Bijoya Paul, Mette Galsgaard Malle, Guillermo Montoya, Troels Christian Petersen, Nikos S Hatzakis
Publikováno v:
eLife, Vol 9 (2020)
Single-molecule Förster Resonance energy transfer (smFRET) is an adaptable method for studying the structure and dynamics of biomolecules. The development of high throughput methodologies and the growth of commercial instrumentation have outpaced th
Externí odkaz:
https://doaj.org/article/14bc36d25b3049558f5feb574e7c03a3
Autor:
M. C. A. S. Hadzic, C. de Lannoy, Don C. Lamb, D. Dunukara, R. K. O. Sigel, George L. Hamilton, Sonja Schmid, Hugo Sanabria, D. A. Erie, Pengning Xu, L. Kisley, J. Schimpf, Johannes Thomsen, Thorsten Hugel, Nikos S. Hatzakis, C. A. M. Seidel, M. Götz, Simon Wanninger, Thorben Cordes, Keith Weninger, C. Mahn, J. Chen, Christian Gebhardt, Anders Barth, Soeren S-R Bohr, L. Vollmar, R. Börner, Magnus Berg Sletfjerding, Dick de Ridder
Publikováno v:
bioRxiv
Single-molecule FRET (smFRET) is a versatile technique to study the dynamics and function of biomolecules since it makes nanoscale movements detectable as fluorescence signals. The powerful ability to infer quantitative kinetic information from smFRE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358d90bf47089b2d927807076bcb8915
https://doi.org/10.1101/2021.11.23.469671
https://doi.org/10.1101/2021.11.23.469671
Autor:
Sara Thodberg, Rita Del Giudice, Matias E. Moses, Tomas Laursen, Nikos S. Hatzakis, Amit V. Pandey, Yanet G. Bustamante, Flemming Jørgensen, Maria Natalia Rojas Velazquez, Cecilie Cetti Hansen, Shaheena Parween, Birger Lindberg Møller, Simon Bo Jensen, Camilla Knudsen, Magnus Berg Sletfjerding, Philip M. Lund, Johannes Thomsen, Patricia Rodríguez Castaño
Publikováno v:
Jensen, Simon Bo; Thodberg, Sara; Parween, Shaheena; Moses, Matias E.; Hansen, Cecilie C.; Thomsen, Johannes; Sletfjerding, Magnus B.; Knudsen, Camilla; Del Giudice, Rita; Lund, Philip M.; Castaño, Patricia R.; Bustamante, Yanet G.; Rojas Velazquez, Maria Natalia; Jørgensen, Flemming Steen; Pandey, Amit Vikram; Laursen, Tomas; Møller, Birger Lindberg; Hatzakis, Nikos S. (2021). Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase. Nature Communications, 12(1), p. 2260. Springer Nature 10.1038/s41467-021-22562-w
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Jensen, S B, Thodberg, S, Parween, S, Moses, M E, Hansen, C C, Thomsen, J, Sletfjerding, M B, Knudsen, C, Del Giudice, R, Lund, P M, Castaño, P R, Bustamante, Y G, Velazquez, M N R, Jørgensen, F S, Pandey, A V, Laursen, T, Møller, B L & Hatzakis, N S 2021, ' Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase ', Nature Communications, vol. 12, no. 1, 2260 . https://doi.org/10.1038/s41467-021-22562-w
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Jensen, S B, Thodberg, S, Parween, S, Moses, M E, Hansen, C C, Thomsen, J, Sletfjerding, M B, Knudsen, C, Del Giudice, R, Lund, P M, Castaño, P R, Bustamante, Y G, Velazquez, M N R, Jørgensen, F S, Pandey, A V, Laursen, T, Møller, B L & Hatzakis, N S 2021, ' Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase ', Nature Communications, vol. 12, no. 1, 2260 . https://doi.org/10.1038/s41467-021-22562-w
Metabolic control is mediated by the dynamic assemblies and function of multiple redox enzymes. A key element in these assemblies, the P450 oxidoreductase (POR), donates electrons and selectively activates numerous (>50 in humans and >300 in plants)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01559cb2dc61b0b1595ccbe1e3266cd4
https://boris.unibe.ch/155910/1/2021_NatureCommunications_s41467-021-22562-w.pdf
https://boris.unibe.ch/155910/1/2021_NatureCommunications_s41467-021-22562-w.pdf
Autor:
Mette Galsgaard Malle, Simon Bo Jensen, Magnus Berg Sletfjerding, Bijoya Paul, Stefano Stella, Nikos S. Hatzakis, Guillermo Montoya, Johannes Thomsen, Troels Petersen
Publikováno v:
Thomsen, J, Sletfjerding, M B, Jensen, S B, Stella, S, Paul, B, Malle, M G, Montoya, G, Petersen, T C & Hatzakis, N S 2020, ' DeepFRET, a software for rapid and automated single-molecule FRET data classification using deep learning ', eLife, vol. 9, e60404 . https://doi.org/10.7554/eLife.60404
eLife, Vol 9 (2020)
eLife
eLife, Vol 9 (2020)
eLife
Single-molecule Förster Resonance energy transfer (smFRET) is an adaptable method for studying the structure and dynamics of biomolecules. The development of high throughput methodologies and the growth of commercial instrumentation have outpaced th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3922ea6b669752530eeac5d9a26de37
https://curis.ku.dk/portal/da/publications/deepfret-a-software-for-rapid-and-automated-singlemolecule-fret-data-classification-using-deep-learning(80636110-27a3-4088-b16e-55d0b37bee9a).html
https://curis.ku.dk/portal/da/publications/deepfret-a-software-for-rapid-and-automated-singlemolecule-fret-data-classification-using-deep-learning(80636110-27a3-4088-b16e-55d0b37bee9a).html
Autor:
Mette Galsgaard Malle, Guillermo Montoya, Troels Petersen, Nikos S. Hatzakis, Bijoya Paul, Johannes Thomsen, Stefano Stella, Simon Bo Jensen, Magnus Berg Sletfjerding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b51eaf6276223246736030b47e7424
https://doi.org/10.7554/elife.60404.sa2
https://doi.org/10.7554/elife.60404.sa2
Autor:
Tomas Laursen, Cecilie Hurup Hansen, Matias E. Moses, Nikos S. Hatzakis, Yanet G. Bustamante, Birger Lindberg Møller, Sara Thodberg, Johannes Thomsen, Rita Del Giudice, Amit V. Pandey, Simon Storgård Jensen, Shaheena Parween, Flemming Jørgensen, Camilla Knudsen, Patricia Rodríguez Castaño, Philip M. Lund, Magnus Berg Sletfjerding
Metabolic control is mediated by the dynamic assemblies and function of multiple redox enzymes. A key element in these assemblies, the P450 oxidoreductase (POR), donates electrons and selectively activates numerous (>50 in humans and >300 in plants)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::506f2fd2a850a675d5fff2d23048ef7f
https://doi.org/10.21203/rs.3.rs-75642/v1
https://doi.org/10.21203/rs.3.rs-75642/v1
Autor:
Simon Bo Jensen, Sara Thodberg, Shaheena Parween, Matias E. Moses, Cecilie C. Hansen, Johannes Thomsen, Magnus B. Sletfjerding, Camilla Knudsen, Rita Del Giudice, Philip M. Lund, Patricia R. Castaño, Yanet G. Bustamante, Flemming S. Jørgensen, Amit V. Pandey, Tomas Laursen, Birger Lindberg Møller, Nikos S. Hatzakis
Metabolic control is mediated by the dynamic assemblies and function of multiple redox enzymes. A key element in these assemblies, the P450 oxidoreductase (POR), donates electrons and selectively activates numerous (>50 in humans and >300 in plants)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ecc72bd57dda0776a6881d7d81e82b5
https://doi.org/10.1101/2020.09.23.310391
https://doi.org/10.1101/2020.09.23.310391