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pro vyhledávání: '"Johannes Teffera"'
Autor:
Linda L. Chang, Plato A. Magriotis, Theodore M. Kamenecka, John A. Schmidt, David N. Young, Ralph A. Stearns, Sharon Tong, Linda A. Egger, Philippe L. Durette, Adria Colletti, Ermengilda McCauley, Kathryn A. Lyons, Johannes Teffera, Richard A. Mumford, Jonathan E. Wilson, Stephen E. de Laszlo, Dorothy Levorse, Linus S. Lin, Judy Fenyk-Melody, Bing Li, Ginger X. Yang, Nancy J. Kevin, William K. Hagmann, Thomas J. Lanza, Malcolm MacCoss, Stella H. Vincent, Karen Owens, Gail Van Riper, Philip Kim, Ihor E. Kopka, Sander G. Mills, Usha Kidambi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:2709-2713
Directed screening of a carboxylic acid-containing combinatorial library led to the discovery of potent inhibitors of the integrin VLA-4. Subsequent optimization by solid-phase synthesis afforded a series of sulfonylated dipeptide inhibitors with str