Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Johannes Rolf Streffer"'
Autor:
Gerald Novak, Johannes Rolf Streffer, Maarten Timmers, David Henley, H. Robert Brashear, Jennifer Bogert, Alberto Russu, Luc Janssens, Ina Tesseur, Luc Tritsmans, Luc Van Nueten, Sebastiaan Engelborghs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2020)
Abstract Background Atabecestat, a potent brain-penetrable inhibitor of BACE1 activity that reduces CSF amyloid beta (Aβ), was developed for oral treatment for Alzheimer’s disease (AD). The long-term safety and effect of atabecestat on cognitive p
Externí odkaz:
https://doaj.org/article/247a92d1c31a4e54b2ea3153ba65cedc
Autor:
Maarten Timmers, Johannes Rolf Streffer, Alberto Russu, Yushin Tominaga, Hiroko Shimizu, Ayako Shiraishi, Kanaka Tatikola, Pascale Smekens, Anne Börjesson-Hanson, Niels Andreasen, Jorge Matias-Guiu, Miquel Baquero, Mercè Boada, Ina Tesseur, Luc Tritsmans, Luc Van Nueten, Sebastiaan Engelborghs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Background β-Secretase enzyme (BACE) inhibition has been proposed as a priority treatment mechanism for Alzheimer’s disease (AD), but treatment initiation may need to be very early. We present proof of mechanism of atabecestat (also known
Externí odkaz:
https://doaj.org/article/29adc1da679f4c53b4ec494c0c1dcf5e
Publikováno v:
Alzheimer's & Dementia. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d6c289a12e72dc0de91caad52f22247
https://doi.org/10.1016/j.jalz.2014.05.1560
https://doi.org/10.1016/j.jalz.2014.05.1560
Autor:
Enchi Liu, Ajibade O. Ashaye, Karin Travers, Lauren Strand, Kelly Olsson, Gian Luca Tanna, Kevin Booth, Scot Styren, H. Robert Brashear, Johannes Rolf Streffer
Publikováno v:
Alzheimer's & Dementia. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa3de307b4906027cf749ee36a2d98c7
https://doi.org/10.1016/j.jalz.2014.05.382
https://doi.org/10.1016/j.jalz.2014.05.382