Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Johannes Poms"'
Autor:
Stephan Sacher, Johannes Poms, Michael Dekner, Sabine Wallner-Mang, Martin Vogt, Johannes G. Khinast, Robert Schennach
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100101- (2021)
The presence of particulate matter in parenteral products is a major concern since it affects the patients' safety and is one of the main reasons for product recalls. Conventional quality control is based on a visual inspection, which is a labour-int
Externí odkaz:
https://doaj.org/article/c7b003f8490e4d46a7c66157186484e3
Autor:
Martin Spoerk, Ioannis Koutsamanis, Josip Matić, Simone Eder, Carolina Patricia Alva Zúñiga, Johannes Poms, Jesús Alberto Afonso Urich, Raymar Andreína Lara García, Klaus Nickisch, Karin Eggenreich, Andreas Berghaus, Kathrin Reusch, Yorick Relle, Johannes Khinast, Amrit Paudel
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 588 (2020)
To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity
Externí odkaz:
https://doaj.org/article/68264e93ced746988a89d9fb178a2e77
Publikováno v:
International Journal of Pharmaceutics. 641:123038
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e63be798a549dbbb08514d11bbb7d8
https://doi.org/10.1016/j.ijpharm.2023.123038
https://doi.org/10.1016/j.ijpharm.2023.123038
Publikováno v:
Reaction Chemistry & Engineering. 5:677-684
Inline benchtop NMR analysis is established as a powerful tool for reaction monitoring, but its capabilities are somewhat limited by low spectral resolution, often leading to overlapping peaks and difficulties in quantification. Using a multivariate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6424d3337dd7aa43c9e41c9371858315
https://doi.org/10.1039/d0re00048e
https://doi.org/10.1039/d0re00048e
Publikováno v:
International journal of pharmaceutics. 613
The implementation of continuous pharmaceutical manufacturing requires advanced control strategies rather than traditional end product testing or an operation within a small range of controlled parameters. A high level of automation based on process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4556c192a885355cae2dee523de6de
https://pubmed.ncbi.nlm.nih.gov/34952147
https://pubmed.ncbi.nlm.nih.gov/34952147
Autor:
Matthias Nixdorf, Robert Schennach, Johannes Poms, Stephan Sacher, Johannes Khinast, Sabine Wallner-Mang, Michael Dekner, Ines Janssen
Publikováno v:
Pharmaceutical Development and Technology. 24:739-750
An undesirable characteristic in lyophilized parenteral products is the potential presence of particulate matter in the final product, which may affect patient safety. In this study, quality risk management tools described in the International Confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda0334644b25f8a1a4f48de64abfa8e
https://doi.org/10.1080/10837450.2019.1585449
https://doi.org/10.1080/10837450.2019.1585449
Autor:
Kathrin Reusch, Raymar Andreína Lara García, Jesús Alberto Afonso Urich, Carolina Patricia Alva Zúñiga, Johannes Khinast, Josip Matić, Amrit Paudel, Karin Eggenreich, Andreas Berghaus, Johannes Poms, Simone Eder, Martin Spoerk, Yorick Relle, Klaus Nickisch, Ioannis Koutsamanis
Publikováno v:
Pharmaceutics, Vol 12, Iss 588, p 588 (2020)
Pharmaceutics
Volume 12
Issue 6
Pharmaceutics
Volume 12
Issue 6
To avoid any type of cross-contamination, residue-free production equipment is of utmost importance in the pharmaceutical industry. The equipment cleaning for continuous processes such as hot melt extrusion (HME), which has recently gained popularity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb9d33b6e6b82f09d1b9698c7d62385
https://www.mdpi.com/1999-4923/12/6/588
https://www.mdpi.com/1999-4923/12/6/588
Autor:
Selma Celikovic, Jakob Rehrl, Johannes Poms, Sharareh Salar-Behzadi, Martin Horn, Johannes Khinast, Stephan Sacher, Julia Kruisz, Gerald Stark, Hannes Berger, Martin Sipek, Martin Kirchengast
Publikováno v:
European Journal of Pharmaceutical Sciences. 142:105097
The objective of this study was to develop a novel closed-loop controlled continuous tablet manufacturing line, which first uses hot melt extrusion (HME) to produce pellets based on API and a polymer matrix. Such systems can be used to make complex p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e134584e9ef5d6774bd5a75bb1c9486
https://doi.org/10.1016/j.ejps.2019.105097
https://doi.org/10.1016/j.ejps.2019.105097
Autor:
Johan Remmelgas, Anssi-Pekka Karttunen, Anders Sparén, Pirjo Tajarobi, W-K. Hsiao, Staffan Folestad, L. Martin De Juan, Stephan Sacher, Susanna Abrahmsén-Alami, Håkan Wikström, Johannes Poms, Ossi Korhonen, C. Ruiz Samblás, Magnus Fransson
Publikováno v:
International Journal of Pharmaceutics. 574:118882
The aim of the current study was to characterize the robustness of an integrated continuous direct compression (CDC) line against disturbances from feeding, i.e. impulses of API and short step disturbances. These disturbances mimicked typical variati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df191874e07421b7adb4ace588c010d
https://doi.org/10.1016/j.ijpharm.2019.118882
https://doi.org/10.1016/j.ijpharm.2019.118882
Autor:
Karl Lohner, Lisa-Marie Schaden, Peter Laggner, Johannes Poms, Stephan Sacher, Sharareh Salar-Behzadi, Johannes Khinast, Miriam Wimmer-Teubenbacher
Publikováno v:
Pharmaceutical research. 35(7)
The effect of different irradiation doses on the structure and activity of lyophilized powders of Hen Egg-White Lysozyme (HEWL) and alcohol dehydrogenase (ADH) was investigated using these substances as models for robust and sensitive proteins, respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb904244bdd80f9ef6af1e252c843da9
https://pubmed.ncbi.nlm.nih.gov/29736628
https://pubmed.ncbi.nlm.nih.gov/29736628