Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Johannes Pill"'
Autor:
Daniel Schock-Kusch, Stefania Geraci, Esther Ermeling, Yury Shulhevich, Carsten Sticht, Juergen Hesser, Dzmitry Stsepankou, Sabine Neudecker, Johannes Pill, Roland Schmitt, Anette Melk
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71519 (2013)
Measuring renal function in laboratory animals using blood and/or urine sampling is not only labor-intensive but puts also a strain on the animal. Several approaches for fluorescence based transcutaneous measurement of the glomerular filtration rate
Externí odkaz:
https://doaj.org/article/59478e21424b4ccda58b31867968dc3f
Autor:
Rodeghiero Federica, Jiaguo Huang, Norbert Gretz, Stefanie Weinfurter, Johannes Pill, Rossana Perciaccante, Cristina Daniele, Leopoldo Della Ciana
Publikováno v:
Chemical Science. 8:2652-2660
We developed novel zwitterionic near infrared (NIR) fluorescent agents (ABZWCY-HPβCD and AAZWCY-HPβCD), which exhibit favorable hydrophilicity, low plasma protein binding, high stability and non-toxicity. These attractive characteristics ensure tha
Autor:
Lena William-Olsson, Ralf Heinrich, Daniel Schock-Kusch, Yury Shulhevich, Jochen Friedemann, Johannes Pill, Matthias Raedle
Publikováno v:
Kidney International. 90:1377-1385
Transcutaneous measurement of the glomerular filtration rate ( t GFR) is now frequently used in animal studies. t GFR allows consecutive measurements on the same animal, including multiple measurements on a daily basis, because no blood sampling is r
Autor:
Yury Shulhevich, Daniel Schock-Kusch, Johannes Pill, Friederike Hoecklin, Dzmitry Stsepankou, Norbert Gretz, Maliha Sadick, Qing Xie, Stefan Koenig, Juergen Hesser
Publikováno v:
Kidney International. 79(11):1254-1258
Determination of the urinary or plasma clearance of exogenous renal markers, such as inulin or iohexol, is considered to be the gold standard for glomerular filtration rate (GFR) measurement. Here, we describe a technique allowing determination of re
Autor:
Guenter Claus, Christel Weiß, Nadja Henninger, Daniel Schock-Kusch, Maliha Sadick, Johannes Pill, Bettina Kraenzlin, Norbert Gretz, Hans-Martin Kloetzer
Publikováno v:
Nephrology Dialysis Transplantation. 24:2997-3001
Background Inulin/sinistrin (I/S) clearance is a gold standard for an accurate assessment of glomerular filtration rate (GFR). Here we describe and validate an approach for a transcutaneous determination of GFR by using fluorescein-isothiocyanate-lab
Autor:
Kirstin Meyer, Johannes Pill
Publikováno v:
Cardiovascular Drug Reviews. 17:246-264
Publikováno v:
Kidney International. 69:60-67
Recombinant human erythropoietin (rhEPO) is used to treat anemia in chronic renal insufficiency. Erythropoietin (EPO) immunogenicity can lead to EPO-resistant anemia. Conjugating proteins with polyethylene glycol (PEG) can prolong elimination half-li
Autor:
Carsten Deus, Hans-Martin Kloetzer, Johannes Pill, Uwe Kraemer, Norbert Gretz, Julia Jander, Tim Sattelkau, Maliha Sadick, Bettina Kraenzlin
Publikováno v:
European Journal of Medicinal Chemistry. 40:1056-1061
There is an obvious and growing medical need for an accurate and easy to handle determination of glomerular filtration rate (GFR) for a broad spectrum of indications. Newly synthesized fluorescein-isothiocyanate (FITC)-sinistrin (FS) with various deg
Publikováno v:
Diabetes Technology & Therapeutics. 7:163-173
The continuous monitoring of glucose allows for tighter control of the glucose concentration and thus may prevent hyper- and hypoglycemia as well as long-term complications of diabetes. While most current systems depend on the transport of fluid to a
Autor:
Stefania, Geraci, Zeneida, Herrera-Pérez, Jianguo, Huang, Stefanie, Weinfurter, Sabine, Neudecker, Yury, Shulhevich, Jochen, Friedemann, Johannes, Pill, Norbert, Gretz
Publikováno v:
Studies in health technology and informatics. 200
Glomerular filtration rate (GFR) is considered the best parameter for the assessment of renal function, being usually determined on the basis of urine or plasma clearance of exogenous renal markers. The common methodology is invasive, time consuming