Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Johannes P, Mouton"'
Autor:
Cristina Mesa-Vieira, Christiane Didden, Michael Schomaker, Johannes P. Mouton, Naomi Folb, Leigh L. van den Heuvel, Chiara Gastaldon, Morna Cornell, Mpho Tlali, Reshma Kassanjee, Oscar H. Franco, Soraya Seedat, Andreas D. Haas
Publikováno v:
Epidemiology and Psychiatric Sciences, Vol 33 (2024)
Abstract Aims Prior research, largely focused on US male veterans, indicates an increased risk of cardiovascular disease among individuals with post-traumatic stress disorder (PTSD). Data from other settings and populations are scarce. The objective
Externí odkaz:
https://doaj.org/article/481226bd85604a03a597396a6324f1ad
Autor:
Andrea L Jorgensen, Catherine Orrell, Catriona Waitt, Cheng-Hock Toh, Christine Sekaggya-Wiltshire, Dyfrig A Hughes, Elizabeth Allen, Emmy Okello, Gayle Tatz, Giovanna Culeddu, Innocent G Asiimwe, Jerome Roy Semakula, Johannes P Mouton, Karen Cohen, Marc Blockman, Mohammed Lamorde, Munir Pirmohamed
Publikováno v:
JMIR Research Protocols, Vol 12, p e46710 (2023)
BackgroundThe quality of warfarin anticoagulation among Sub-Saharan African patients is suboptimal. This is due to several factors, including a lack of standardized dosing algorithms, difficulty in providing timely international normalized ratio (INR
Externí odkaz:
https://doaj.org/article/8aa9d5caf1144261bbc13fcb1b01ef6e
Autor:
Innocent G. Asiimwe, Marc Blockman, Karen Cohen, Clint Cupido, Claire Hutchinson, Barry Jacobson, Mohammed Lamorde, Jennie Morgan, Johannes P. Mouton, Doreen Nakagaayi, Emmy Okello, Elise Schapkaitz, Christine Sekaggya‐Wiltshire, Jerome R. Semakula, Catriona Waitt, Eunice J. Zhang, Andrea L. Jorgensen, Munir Pirmohamed
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 20-29 (2022)
Abstract Warfarin remains the most widely prescribed oral anticoagulant in sub‐Saharan Africa. However, because of its narrow therapeutic index, dosing can be challenging. We have therefore (a) evaluated and compared the performance of 21 machine
Externí odkaz:
https://doaj.org/article/a70a4a18bb0f45898c40e56846101497
Autor:
Innocent G. Asiimwe, Marc Blockman, Karen Cohen, Clint Cupido, Claire Hutchinson, Barry Jacobson, Mohammed Lamorde, Jennie Morgan, Johannes P. Mouton, Doreen Nakagaayi, Emmy Okello, Elise Schapkaitz, Christine Sekaggya-Wiltshire, Jerome R. Semakula, Catriona Waitt, Eunice J. Zhang, Andrea L. Jorgensen, Munir Pirmohamed
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Diversity in pharmacogenomic studies is poor, especially in relation to the inclusion of black African patients. Lack of funding and difficulties in recruitment, together with the requirement for large sample sizes because of the extensive genetic di
Externí odkaz:
https://doaj.org/article/1b61f543f5f540d0bb36d6daa02e5b11
Autor:
Johannes P. Mouton, Nicole Jobanputra, Christine Njuguna, Hannah Gunter, Annemie Stewart, Ushma Mehta, Sa'ad Lahri, Richard Court, Ehimario Igumbor, Gary Maartens, Karen Cohen
Publikováno v:
African Journal of Emergency Medicine, Vol 11, Iss 1, Pp 46-52 (2021)
Introduction: South Africa has the world's largest antiretroviral treatment programme, which may contribute to the adverse drug reaction (ADR) burden. We aimed to determine the proportion of adult non-trauma emergency unit (EU) presentations attribut
Externí odkaz:
https://doaj.org/article/3e285ff1602e4504a5b308a6a71a64d6
Autor:
Johannes P. Mouton, Melony C. Fortuin-de Smidt, Nicole Jobanputra, Ushma Mehta, Annemie Stewart, Reneé de Waal, Karl-Günter Technau, Andrew Argent, Max Kroon, Christiaan Scott, Karen Cohen
Publikováno v:
BMC Pediatrics, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background The high HIV prevalence in South Africa may potentially be shaping the local adverse drug reaction (ADR) burden. We aimed to describe the prevalence and characteristics of serious ADRs at admission, and during admission, to two So
Externí odkaz:
https://doaj.org/article/0cc6203e4e07435db654e5b55ce65e4e
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract We aimed to summarize and describe the burden of serious adverse drug reactions (ADRs) in sub‐Saharan Africa (SSA) in the era of antiretroviral therapy. We searched Medline, CINAHL, Africa‐Wide Information, Scopus, and Web of Science, wi
Externí odkaz:
https://doaj.org/article/bbece76661c8408c9fe6227af34a7d97
Autor:
Jerome Roy Semakula, Johannes P Mouton, Andrea Jorgensen, Claire Hutchinson, Shaazia Allie, Lynn Semakula, Neil French, Mohammed Lamorde, Cheng-Hock Toh, Marc Blockman, Christine Sekaggya-Wiltshire, Catriona Waitt, Munir Pirmohamed, Karen Cohen
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227458 (2020)
INTRODUCTION:Warfarin is the most commonly prescribed oral anticoagulant in sub-Saharan Africa and requires ongoing monitoring. The burden of both infectious diseases and non-communicable diseases is high and medicines used to treat comorbidities may
Externí odkaz:
https://doaj.org/article/d501d1f8c9fe4eb6b772a772396b4760
Autor:
Andrea Jorgensen, Catherine Orrell, Catriona Waitt, Cheng-Hock Toh, Christine Sekaggya, Dyfrig Hughes, Elizabeth Allen, Emmy Okello, Gayle Tatz, Giovanna Celuddu, Innocent G Asiimwe, Jerome Roy Semakula, Johannes P Mouton, Karen Cohen, Marc Blockman, Mohammed Lamorde, Munir Pirmohamed
BACKGROUND The quality of warfarin anticoagulation among sub-Saharan African patients is sub-optimal. This is due to several factors including lack of standardized dosing algorithms; difficulty in providing timely INR results; lack of patient feedbac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684c2af048698ed5e45e09845dcc0d96
https://doi.org/10.2196/preprints.46710
https://doi.org/10.2196/preprints.46710
Autor:
Innocent G. Asiimwe, Marc Blockman, Karen Cohen, Clint Cupido, Claire Hutchinson, Barry Jacobson, Mohammed Lamorde, Jennie Morgan, Johannes P. Mouton, Doreen Nakagaayi, Emmy Okello, Elise Schapkaitz, Christine Sekaggya‐Wiltshire, Jerome R. Semakula, Catriona Waitt, Eunice J. Zhang, Andrea L. Jorgensen, Munir Pirmohamed
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 20-29 (2022)
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 1, Pp 20-29 (2022)
Warfarin remains the most widely prescribed oral anticoagulant in sub‐Saharan Africa. However, because of its narrow therapeutic index, dosing can be challenging. We have therefore (a) evaluated and compared the performance of 21 machine‐learning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d0abb811928478061758404886b5ea
https://doi.org/10.1002/psp4.12740
https://doi.org/10.1002/psp4.12740