Zobrazeno 1 - 10
of 822
pro vyhledávání: '"Johannes Oldenburg"'
Autor:
Ilja Oomen, Amal Abdi, Ricardo M. Camelo, Fábia M.R.A. Callado, Luany E.M. Carvalho, Ilenia L. Calcaterra, Manuel Carcao, Giancarlo Castaman, Jeroen C.J. Eikenboom, Kathelijn Fischer, Vivian K.B. Franco, Martijn W. Heymans, Frank W.G. Leebeek, David Lillicrap, Cláudia S. Lorenzato, Maria Elisa Mancuso, Davide Matino, Matteo N.D. Di Minno, Alex B. Mohseny, Johannes Oldenburg, Suely Meireles Rezende, Georges-Etienne Rivard, Natalia Rydz, Saskia E.M. Schols, Jan Voorberg, Karin Fijnvandraat, Samantha C. Gouw
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102580- (2024)
Background: Inhibitor eradication to restore factor (F)VIII efficacy is the treatment goal for persons with severe hemophilia A (HA) and inhibitors. Immune tolerance induction (ITI) is demanding and successful in about 70% of people. Until now, it ha
Externí odkaz:
https://doaj.org/article/81986c3b0b0948108260f0f7bf03d9f4
Autor:
Christian Herbert Burgmann, Ulrich J. Sachs, Karolin Trautmann-Grill, Christian Pfrepper, Paul Knöbl, Richard Greil, Johannes Oldenburg, Wolfgang Miesbach, Katharina Holstein, Hermann Eichler, Patrick Möhnle, Matthias Höpting, Christiane Dobbelstein, Robert Klamroth, Andreas Tiede
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102565- (2024)
Background: Persons with acquired hemophilia A are often older and suffer from comorbidity or frailty. Little is known about the impact on clinically relevant outcomes of acquired hemophilia A. Objectives: To assess the relevance of age, physical per
Externí odkaz:
https://doaj.org/article/f7f877abe5424c50a5a1fb6bb6878e21
Autor:
Christian Qvigstad, Lars Q. Sørensen, Geir E. Tjønnfjord, Pål André Holme, Ingrid Pabinger, Cedric Hermans, Roseline d’Oiron, Robert Klamroth, Johannes Oldenburg, Natascha Marquardt, Peter Staritz, Olga Katsarou, Uri Martinowitz, Aharon Lubetsky, Gili Kenet, Annarita Tagliaferri, Maria Elisa Mancuso, Roger Schutgens, Pål André HolmE, Jerzy Windyga, Irena Zupan, Victor Jimenez Yuste, Ramiro Nunez, Philippe de Moerloose, Erik Berntorp, Jan Astermark, Campbell Tait, Gerry Dolan
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 5, Pp 102514- (2024)
Background: People with hemophilia often experience pain and suffer from comorbidities related to their bleeding disorder. Consequently, unemployment due to disability is prevalent among people with hemophilia. Objectives: To explore associations bet
Externí odkaz:
https://doaj.org/article/bbbcde5173814e1f8d9095c20136a013
Autor:
Heiko Rühl, Christian Bode, Tobias Becher, Sebastian Eckert, Ghaith Mohsen, Hannah L. McRae, Jens Müller, Sara Reda, Dirk Loßnitzer, Johannes Oldenburg, Christian Putensen, Bernd Pötzsch
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1982 (2024)
Sepsis-associated coagulopathy increases risk of mortality. Impairment of the anticoagulant protein C (PC) pathway may contribute to the thrombotic phenotype in coronavirus disease 2019 (COVID-19) sepsis. This study assessed the functionality of this
Externí odkaz:
https://doaj.org/article/e0be3497eded43f498675cd68cd8484d
Autor:
Muhammad Ahmer Jamil, Rawya Al-Rifai, Nicole Nuesgen, Janine Altmüller, Johannes Oldenburg, Osman El-Maarri
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Coagulation Factor VIII (FVIII) plays a pivotal role in the coagulation cascade, and deficiencies in its levels, as seen in Hemophilia A, can lead to significant health implications. Liver sinusoidal endothelial cells (LSECs) are the ma
Externí odkaz:
https://doaj.org/article/7213597cbc6f4b008dd82651c72b8c20
Autor:
Richard Lemons, Michael Wang, Julie Curtin, Lynda Mae Lepatan, Christoph Male, Flora Peyvandi, Mario von Depka Prondzinski, Rongrong Wang, William McKeand, Wilfried Seifert, Johannes Oldenburg
Publikováno v:
TH Open, Vol 08, Iss 01, Pp e155-e163 (2024)
Introduction Recombinant fusion protein linking coagulation factor IX (FIX) with albumin (rIX-FP) has been shown to be an effective, well-tolerated treatment for patients with severe hemophilia B who had previously received factor replacement therapy
Externí odkaz:
https://doaj.org/article/9b8f1fd5ab434c34948cf4c09b501cde
Autor:
Carmen Escuriola Ettingshausen, Cedric Hermans, Pål A. Holme, Ana R. Cid, Kate Khair, Johannes Oldenburg, Claude Négrier, Jaco Botha, Aurelia Lelli, Jerzy Windyga
Publikováno v:
Therapeutic Advances in Hematology, Vol 14 (2023)
Background: The bypassing agent, activated prothrombin complex concentrate [aPCC, FEIBA (factor VIII inhibitor bypass activity); Baxalta US Inc, a Takeda company, Lexington, MA, USA], is indicated for the treatment of bleeding episodes, perioperative
Externí odkaz:
https://doaj.org/article/8d1f01490a1242c6b4f52dbc1424e3df
Autor:
Barbara Preisler, Behnaz Pezeshkpoor, Anja Merzenich, Sandra Ohlenforst, Heiko Rühl, Vytautas Ivaškevičius, Ute Scholz, Hagen Bönigk, Wolfgang Eberl, Barbara Zieger, Anna Pavlova, Johannes Oldenburg
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2384 (2024)
Congenital factor VII (FVII) deficiency is a rare genetic bleeding disorder characterized by deficient or reduced activity of coagulation FVII. It is caused by genetic variants in the F7 gene. We aimed to evaluate the rate of detection of pathogenic
Externí odkaz:
https://doaj.org/article/2b277c9610dd4be19f21749ffa1e7139
Autor:
Jens Müller, Nasim Shahidi Hamedani, Hannah L. McRae, Heiko Rühl, Johannes Oldenburg, Bernd Pötzsch
Publikováno v:
ACS Omega, Vol 7, Iss 35, Pp 30801-30806 (2022)
Externí odkaz:
https://doaj.org/article/bad1bd09eb4f4f59bb384dd9dfa4ea22
Autor:
Johannes Oldenburg, Susan Halimeh, Georgina W. Hall, Robert Klamroth, Pascual Marco Vera, Martina Jansen, Mary Mathias
Publikováno v:
TH Open, Vol 07, Iss 02, Pp e110-e116 (2023)
Background The efficacy, safety, and immunogenicity of each of Octapharma's factor VIII (FVIII) products, Nuwiq, octanate, and wilate, have been investigated in previously untreated patients (PUPs) with severe hemophilia A in prospective clinical tri
Externí odkaz:
https://doaj.org/article/2ee1e59b90904ba28b4e04d4f62e900a