Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Johannes Nimpf"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
The canonical Reelin signaling cascade regulates correct neuronal layering during embryonic brain development. Details of this pathway are still not fully understood since the participating components are highly variable and create a complex mixture
Externí odkaz:
https://doaj.org/article/3e2ea3a3116446c986c7380e24419834
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1451-1456 (2007)
Apolipoprotein A-V (apoA-V) affects plasma triglyceride (TG) levels; however, the properties of apoA-V that mediate its action(s) are still incompletely understood. It is unclear how apoA-V, whose plasma concentration is extremely low, can affect the
Externí odkaz:
https://doaj.org/article/0c53f55909eb40a88d93e5eaff79d44b
Autor:
Susanna Hummel, Edward G. Lynn, Andreas Osanger, Satoshi Hirayama, Johannes Nimpf, Wolfgang J. Schneider
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 9, Pp 1633-1642 (2003)
Low levels of expression and sluggish sterol-mediated regulation have been likely reasons for the failure to molecularly characterize a bona fide LDL receptor (LDLR) in egg-laying species to date. The overall structure of the chicken LDLR, delineated
Externí odkaz:
https://doaj.org/article/91ff4f2174b64c4e9f7b0f4a026c5458
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1745, p 1745 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1745, p 1745 (2021)
Disabled 1 (Dab1) is an adapter protein for very low density lipoprotein receptor (VLDLR) and apolipoprotein E receptor 2 (ApoER2) and an integral component of the Reelin pathway which orchestrates neuronal layering during embryonic brain development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e304b529172a6e9c65686025e7f8c141
http://europepmc.org/articles/PMC7916142
http://europepmc.org/articles/PMC7916142
Autor:
Paula Dlugosz, Johannes Nimpf
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3090 (2018)
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3090 (2018)
Apolipoprotein E receptor 2 (ApoER2) and VLDL receptor belong to the low density lipoprotein receptor family and bind apolipoprotein E. These receptors interact with the clathrin machinery to mediate endocytosis of macromolecules but also interact wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e6c26e2279b6b50fc8fd14b4a0803283
http://europepmc.org/articles/PMC6213145
http://europepmc.org/articles/PMC6213145
Autor:
Valeria Balmaceda, Johannes Nimpf, Inmaculada Cuchillo-Ibañez, Javier Sáez-Valero, Juan José Arranz, Trinidad Mata-Balaguer
Publikováno v:
Scientific Reports
Reelin is a signaling protein that plays a crucial role in synaptic function, which expression is influenced by β-amyloid (Aβ). We show that Reelin and Aβ oligomers co-immunoprecipitated in human brain extracts and were present in the same size-ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bfdc410c390d560466f54e99857f08
https://pubmed.ncbi.nlm.nih.gov/27531658
https://pubmed.ncbi.nlm.nih.gov/27531658
Publikováno v:
Biochemical and Biophysical Research Communications. 406:257-261
In laying hens, massive hepatic mobilization of fatty acids is required for the synthesis of oocyte-targeted very-low density lipoproteins (VLDL). The current study aims at identification of enzymes that hydrolyze hepatic acylglycerol stores regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c85f8096406e94ab4d657cebd50933
https://doi.org/10.1016/j.bbrc.2011.02.029
https://doi.org/10.1016/j.bbrc.2011.02.029
Publikováno v:
Journal of Biological Chemistry. 285:4896-4908
ApoER2 and very low density lipoprotein (VLDL) receptor transmit the Reelin signal into target cells of the central nervous system. To a certain extent, both receptors can compensate for each other, and only the loss of both receptors results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e48568ec54790ad536567f3ec4d3425
https://doi.org/10.1074/jbc.m109.025973
https://doi.org/10.1074/jbc.m109.025973
Autor:
Nasha Nassoury, Annik Prat, Johannes Nimpf, Eric Bergeron, Gaétan Mayer, Jadwiga Marcinkiewicz, Suzanne Benjannet, Nabil G. Seidah, Harald Mayer, Steve Poirier
Publikováno v:
Journal of Biological Chemistry. 283:2363-2372
The proprotein convertase PCSK9 gene is the third locus implicated in familial hypercholesterolemia, emphasizing its role in cardiovascular diseases. Loss of function mutations and gene disruption of PCSK9 resulted in a higher clearance of plasma low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eeb19b57065c48ae1ece69fbe3af3f7
https://doi.org/10.1074/jbc.m708098200
https://doi.org/10.1074/jbc.m708098200
Autor:
Andreas Osanger, Sabine Christian, Johannes Nimpf, Hans Heid, Susanna Hummel, Wolfgang J. Schneider
Publikováno v:
Journal of Biological Chemistry. 282:8011-8018
The membranous structure separating the granulosa from theca cells in the developing ovarian follicles of birds is generally perceived as a genuine basement membrane (BM). Previously, we suggested that this membrane is unusual in that it lacks severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c301221ead42d27e329ce4c090889089
https://doi.org/10.1074/jbc.m606029200
https://doi.org/10.1074/jbc.m606029200