Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Johannes M. van Noort"'
Autor:
David W. Hampton, Sandra Amor, David Story, Megan Torvell, Malika Bsibsi, Johannes M. van Noort, Siddarthan Chandran
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Progressive neuronal death during tauopathies is associated with aggregation of modified, truncated or mutant forms of tau protein. Such aggregates are neurotoxic, promote spreading of tau aggregation, and trigger release of pro-inflammatory factors
Externí odkaz:
https://doaj.org/article/2aa29171a7c64b26aa76954d35b5498e
Autor:
Silvia T. Erni, Gabriella Fernandes, Michelle Buri, Michael Perny, Rolf Jan Rutten, Johannes M. van Noort, Pascal Senn, Denis Grandgirard, Marta Roccio, Stephen L. Leib
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Sensorineural hearing loss is the most common long-term deficit after pneumococcal meningitis (PM), occurring in up to 30% of surviving patients. The infection and the following overshooting inflammatory host response damage the vulnerable sensory ce
Externí odkaz:
https://doaj.org/article/2bc8416081e34a35ac71fa5bb7b139d3
Autor:
Hendrikus Boddeke, Paul van der Valk, Johannes M. van Noort, Malika Bsibsi, Markus Kipp, Wouter H. Gerritsen, Inge R. Holtman, Sandra Amor, Bart J. L. Eggen
Publikováno v:
Glia. 65:460-473
The glial stress protein alpha B-crystallin (HSPB5) is an endogenous agonist for Toll-like receptor 2 in CD14+ cells. Following systemic administration, HSPB5 acts as a potent inhibitor of neuroinflammation in animal models and reduces lesion develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f01bae4d1fb50620277028f1271e614
https://doi.org/10.1002/glia.23104
https://doi.org/10.1002/glia.23104
Autor:
Dimitri A. Diavatopoulos, Ella A. Zuiderwijk-Sick, Elles Simonetti, Hans J. P. M. Koenen, Céline van der Putten, Sacha A. F. T. van Hijum, Jeffrey J. Bajramovic, Ad P. IJzerman, Lejla Sukurova, Johannes M. van Noort, Saskia M. Burm, Jennifer Veth
Publikováno v:
Journal of Immunology, 202, 2421-2430
Journal of Immunology, 202, 8, pp. 2421-2430
Journal of Immunology, 202, 8, pp. 2421-2430
TLR-induced signaling potently activates cells of the innate immune system and is subject to regulation at different levels. Inflammatory conditions are associated with increased levels of extracellular adenosine, which can modulate TLR-induced produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc634871be18e0fe56dad6265efdf403
http://hdl.handle.net/2066/202858
http://hdl.handle.net/2066/202858
Publikováno v:
Brain Pathology. 26:248-257
Neurological dysfunction and motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is strongly associated with neuroinflammation reflected by activated microglia and astrocytes in the CNS. In ALS endogenous triggers in the CNS such as aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e9055962660b11b69f6f19740d5d76
https://doi.org/10.1111/bpa.12352
https://doi.org/10.1111/bpa.12352
Autor:
Céline, van der Putten, Jennifer, Veth, Lejla, Sukurova, Ella A, Zuiderwijk-Sick, Elles, Simonetti, Hans J P M, Koenen, Saskia M, Burm, Johannes M, van Noort, Ad P, IJzerman, Sacha A F T, van Hijum, Dimitri, Diavatopoulos, Jeffrey J, Bajramovic
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(8)
TLR-induced signaling potently activates cells of the innate immune system and is subject to regulation at different levels. Inflammatory conditions are associated with increased levels of extracellular adenosine, which can modulate TLR-induced produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a923c8ffb96fc620df25cd372e1efde
https://pubmed.ncbi.nlm.nih.gov/30804043
https://pubmed.ncbi.nlm.nih.gov/30804043
Autor:
Malika Bsibsi, Wouter H. Gerritsen, Inge R. Holtman, Johannes M. van Noort, Paul van der Valk, Peter J. Nacken, Sandra Amor, Laura A. N. Peferoen, Bart J. L. Eggen, Jack van Horssen, Maarten E. Witte
Publikováno v:
Acta Neuropathologica, 128(2), 215-229. SPRINGER
Acta Neuropathologica, 128(2), 215-229. Springer Verlag
Bsibsi, M, Peferoen, L A N, Holtman, I R, Nacken, P J, Gerritsen, W H, Witte, M E, van Horssen, J, Eggen, B J L, van der Valk, P, Amor, S & van Noort, J M 2014, ' Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-gamma and alpha B-crystallin ', Acta Neuropathologica, vol. 128, no. 2, pp. 215-229 . https://doi.org/10.1007/s00401-014-1317-8
Acta Neuropathologica, 128(2), 215-229. Springer Verlag
Bsibsi, M, Peferoen, L A N, Holtman, I R, Nacken, P J, Gerritsen, W H, Witte, M E, van Horssen, J, Eggen, B J L, van der Valk, P, Amor, S & van Noort, J M 2014, ' Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-gamma and alpha B-crystallin ', Acta Neuropathologica, vol. 128, no. 2, pp. 215-229 . https://doi.org/10.1007/s00401-014-1317-8
Activated microglia and macrophages play a key role in driving demyelination during multiple sclerosis (MS), but the factors responsible for their activation remain poorly understood. Here, we present evidence for a dual-trigger role of IFN-gamma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a3cb320cba3eeeaedfc2f86f8b4c07
https://doi.org/10.1007/s00401-014-1317-8
https://doi.org/10.1007/s00401-014-1317-8
Publikováno v:
Immunology, 141(3), 302-313. Wiley-Blackwell
Peferoen, L, Kipp, M, van der Valk, P, van Noort, J M & Amor, S 2014, ' Oligodendrocyte-microglia cross-talk in the central nervous system ', Immunology, vol. 141, no. 3, pp. 302-313 . https://doi.org/10.1111/imm.12163
Peferoen, L, Kipp, M, van der Valk, P, van Noort, J M & Amor, S 2014, ' Oligodendrocyte-microglia cross-talk in the central nervous system ', Immunology, vol. 141, no. 3, pp. 302-313 . https://doi.org/10.1111/imm.12163
Communication between the immune system and the central nervous system (CNS) is exemplified by cross-talk between glia and neurons shown to be essential for maintaining homeostasis. While microglia are actively modulated by neurons in the healthy bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80af12c427c672a16f1ec217f6c1a6c3
https://doi.org/10.1111/imm.12163
https://doi.org/10.1111/imm.12163
Autor:
Johannes M. van Noort, Marjolein Breur, David Baker, Erik Boddeke, Laura A. N. Peferoen, Sandra Amor, Sarah van de Berg, Paul van der Valk, Gareth Pryce, Regina Peferoen-Baert
Publikováno v:
Immunology, 149(2), 146-156. Wiley-Blackwell
Peferoen, L A N, Breur, M, van de Berg, S, Peferoen-Baert, R, Boddeke, E H W G M, van der Valk, P, Pryce, G, van Noort, J M, Baker, D & Amor, S 2016, ' Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice ', Immunology, vol. 149, no. 2, pp. 146-156 . https://doi.org/10.1111/imm.12644
Peferoen, L A N, Breur, M, van de Berg, S, Peferoen-Baert, R, Boddeke, E H W G M, van der Valk, P, Pryce, G, van Noort, J M, Baker, D & Amor, S 2016, ' Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice ', Immunology, vol. 149, no. 2, pp. 146-156 . https://doi.org/10.1111/imm.12644
Current therapies for multiple sclerosis (MS) reduce the frequency of relapses by modulating adaptive immune responses but fail to limit the irreversible neurodegeneration driving progressive disability. Experimental autoimmune encephalomyelitis (EAE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0127d433a2bf1415ca55432d492c5a
https://research.rug.nl/en/publications/f59b4b30-5520-4416-bc7f-c4b0a8283627
https://research.rug.nl/en/publications/f59b4b30-5520-4416-bc7f-c4b0a8283627
Autor:
Inge R, Holtman, Malika, Bsibsi, Wouter H, Gerritsen, Hendrikus W G M, Boddeke, Bart J L, Eggen, Paul, van der Valk, Markus, Kipp, Johannes M, van Noort, Sandra, Amor
Publikováno v:
Glia. 65(3)
The glial stress protein alpha B-crystallin (HSPB5) is an endogenous agonist for Toll-like receptor 2 in CD14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31b3d0d5322ba4ddf0bfdcc57aa6260c
https://pubmed.ncbi.nlm.nih.gov/28063173
https://pubmed.ncbi.nlm.nih.gov/28063173