Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Johannes M. Nitsche"'
Autor:
Johannes M. Nitsche, Gerald B. Kasting
Publikováno v:
Journal of Pharmaceutical Sciences. 111:2093-2106
Interpretation of experiments involving transient solute binding to isolated keratin substrates is analyzed and discussed in terms of their impact on transient permeation of topically-applied compounds through human stratum corneum. The analysis buil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c466f8fa25f4c82d3c6606673c946bca
https://doi.org/10.1016/j.xphs.2021.11.026
https://doi.org/10.1016/j.xphs.2021.11.026
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503f498f5edadd62dcda78c853f43105
https://doi.org/10.1016/j.ejpb.2023.01.025
https://doi.org/10.1016/j.ejpb.2023.01.025
Autor:
Kevin Tonnis, Johannes M. Nitsche, Lijing Xu, Alison Haley, Joanna Jaworska, Gerald B. Kasting
Publikováno v:
International journal of pharmaceutics. 624
To measure progress and evaluate performance of the newest UB/UC/PG skin penetration model we simulated an 18-compound subset of finite dose in vitro human skin permeation data taken from a solvent-deposition study of cosmetic-relevant compounds (Hew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543b33f7af1486cdfb7afec522c3eb3d
https://pubmed.ncbi.nlm.nih.gov/35863596
https://pubmed.ncbi.nlm.nih.gov/35863596
Autor:
Olga Denysova, Johannes M. Nitsche
Publikováno v:
Journal of theoretical biology. 539
This paper develops a detailed model of human and bovine erythrocytes quantifying the dependence of total cell volume upon composition of an aqueous solution in which it is immersed. The cytoplasm is represented as an aqueous solution of hemoglobin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaf6b9fa5b4121d0910b358342843f3
https://pubmed.ncbi.nlm.nih.gov/35051431
https://pubmed.ncbi.nlm.nih.gov/35051431
Autor:
Gerald B. Kasting, Johannes M. Nitsche
Publikováno v:
Journal of pharmaceutical sciences. 107(2)
Partition coefficients between human stratum corneum lipids and water ( K sclip/w ) are collected or deduced from a variety of sources in a manner that approximately doubles the available data compared to the current state-of-the-art model (Hansen et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23a71e24498ac48d0c9798b95206314
https://pubmed.ncbi.nlm.nih.gov/28818392
https://pubmed.ncbi.nlm.nih.gov/28818392
Autor:
Gerald B. Kasting, Johannes M. Nitsche
Publikováno v:
Journal of Pharmaceutical Sciences. 102:2005-2032
Permeability data ( P lip/w ) for liquid crystalline phospholipid bilayers composed of egg lecithin and dimyristoylphosphatidylcholine (DMPC) are analyzed in terms of a mathematical model that accounts for free surface area and chain-ordering effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfef8bc2c31dd7613f48ac1860fcfec
https://doi.org/10.1002/jps.23471
https://doi.org/10.1002/jps.23471
Autor:
Johannes M. Nitsche, Gerald B. Kasting
Publikováno v:
Journal of Pharmaceutical Sciences. 102:136-144
An important series of papers by Xiang, Anderson, and coworkers has established the strong correlation between phospholipid bilayer membrane permeability and the 1,9-decadiene/water partition coefficient over a wide range of compounds, elevating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c61195260cb44273b35b21823d65d66
https://doi.org/10.1002/jps.23342
https://doi.org/10.1002/jps.23342
Publikováno v:
Journal of Pharmaceutical Sciences. 100:2989-2995
New data sets on both (i) equilibrium theophylline (TH) partitioning/binding in stratum corneum and (ii) transient TH diffusion through human epidermis are explained by an extended partition–diffusion model with reversible binding. Data conform to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a657cf98e228800b47ff9c6b6462f2a0
https://doi.org/10.1002/jps.22489
https://doi.org/10.1002/jps.22489
Publikováno v:
Chemical Engineering Science. 66:2019-2041
Essentially all biological membranes and tissues exhibit microscopic heterogeneity in the form of cellular, lamellar or other organization, and molecular diffusion in these materials is frequently slowed by binding to elements of the microstructure (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b114dbceaf6132a442278c16606ea5c
https://doi.org/10.1016/j.ces.2011.01.008
https://doi.org/10.1016/j.ces.2011.01.008
Publikováno v:
Journal of Pharmaceutical Sciences. 96:3024-3051
The full parameterization for the stratum corneum biphasic microtransport model presented previously in this Journal [95:620-648 (2006)] is developed through a combination of fundamental transport theory and calibration with existing data. Of the fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7914ffa47927114ee450c6629fc3154f
https://doi.org/10.1002/jps.20883
https://doi.org/10.1002/jps.20883