Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Johannes M. Freudenberg"'
Autor:
Johannes M. Freudenberg, Zhi Liu, Jennifer Singh, Elizabeth Thomas, Christopher Traini, Deepak K. Rajpal, Christopher J. Sayed
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Hidradenitis suppurativa (HS) is a common, debilitating inflammatory skin disease linked to immune dysregulation and abnormalities in follicular structure and function. Several studies have characterized the transcriptomic profile of affected and una
Externí odkaz:
https://doaj.org/article/c8fc4c02ca044620b28d3d90290c8b14
HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
Autor:
Andrew N. Billin, Samuel E. Honeycutt, Alan V. McDougal, Jaclyn P. Kerr, Zhe Chen, Johannes M. Freudenberg, Deepak K. Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S. Geske, Frank Fang, Bert Yao, Richard V. Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C. Hinken, Alan J. Russell
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Background In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments.
Externí odkaz:
https://doaj.org/article/e1f73e6f4eda4a62a3d79d3777de791e
Autor:
Andrew N. Billin, Samuel E. Honeycutt, Alan V. McDougal, Jaclyn P. Kerr, Zhe Chen, Johannes M. Freudenberg, Deepak K. Rajpal, Guizhen Luo, Henning Fritz Kramer, Robert S. Geske, Frank Fang, Bert Yao, Richard V. Clark, John Lepore, Alex Cobitz, Ram Miller, Kazunori Nosaka, Aaron C. Hinken, Alan J. Russell
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-1 (2018)
Following publication of the original article [1], the authors flagged that there is a discrepancy with the Availability of data and materials statement on page 12 of the article.
Externí odkaz:
https://doaj.org/article/d03026fdb79744668aebcc8fa062fee1
Autor:
David N. Mayhew, Johannes M. Freudenberg, Deepak K. Rajpal, Thierry Olivry, David S. Rubenstein
Publikováno v:
Journal of Investigative Dermatology. 139:968-971
Autor:
Akshay Bareja, Jason A Holt, Guizhen Luo, Calvin Chang, Junyu Lin, Aaron C Hinken, Johannes M Freudenberg, William E Kraus, William J Evans, Andrew N Billin
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90398 (2014)
Satellite cells are the chief contributor to skeletal muscle growth and regeneration. The study of mouse satellite cells has accelerated in recent years due to technical advancements in the isolation of these cells. The study of human satellite cells
Externí odkaz:
https://doaj.org/article/b59f032fb88a4b6cac5f3fde409dca6f
Autor:
Jing Chen, Zhen Hu, Mukta Phatak, John Reichard, Johannes M Freudenberg, Siva Sivaganesan, Mario Medvedovic
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 9, p e1003198 (2013)
Identifying transcription factors (TF) involved in producing a genome-wide transcriptional profile is an essential step in building mechanistic model that can explain observed gene expression data. We developed a statistical framework for constructin
Externí odkaz:
https://doaj.org/article/c4c9bcad41d842abb5563bb115e9351a
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1903
Computational prediction of the clinical success or failure of a potential drug target for therapeutic use is a challenging problem. Novel network propagation algorithms that integrate heterogeneous biological networks are proving useful for drug tar
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989546
Computational prediction of the clinical success or failure of a potential drug target for therapeutic use is a challenging problem. Novel network propagation algorithms that integrate heterogeneous biological networks are proving useful for drug tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6442e531230f4cd4a0e7efb6d8e8228
https://doi.org/10.1007/978-1-4939-8955-3_12
https://doi.org/10.1007/978-1-4939-8955-3_12
Autor:
Alan V. McDougal, John J. Lepore, Samuel E. Honeycutt, Andrew N. Billin, Henning F Kramer, Deepak K. Rajpal, Bert Yao, Zhe Chen, Aaron C. Hinken, Richard V. Clark, Kazunori Nosaka, Ram Miller, Johannes M. Freudenberg, Frank Fang, Robert S. Geske, Alex Cobitz, Guizhen Luo, Jaclyn P. Kerr, Alan J. Russell
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-1 (2018)
Skeletal Muscle
Skeletal Muscle
Background In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments. Hypoxia-i
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Bioinformatics
BMC Bioinformatics
Background The Open Targets Platform integrates different data sources in order to facilitate identification of potential therapeutic drug targets to treat human diseases. It currently provides evidence for nearly 2.6 million potential target-disease