Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Johannes M. Dijkstra"'
Publikováno v:
Fujita Medical Journal, Vol 10, Iss 1, Pp 1-7 (2024)
Distinguished Professor Emeritus Tsuneko Okazaki is a hero of science. Together with her late husband, Professor Reiji Okazaki, she discovered that DNA replication involves the discontinuous synthesis of the DNA lagging strand by intermediates of, wh
Externí odkaz:
https://doaj.org/article/236122dee3734129a133c15ad56af3e1
Autor:
Fumio Takizawa, Keiichiro Hashimoto, Ryuichiro Miyazawa, Yuko Ohta, Ana Veríssimo, Martin F. Flajnik, David Parra, Kotaro Tokunaga, Hiroaki Suetake, J. Oriol Sunyer, Johannes M. Dijkstra
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD4 and LAG-3 are related molecules that are receptors for MHC class II molecules. Their major functional differences are situated in their cytoplasmic tails, in which CD4 has an activation motif and LAG-3 an inhibitory motif. Here, we identify shark
Externí odkaz:
https://doaj.org/article/de4d4f3355de47cb9c19eab95512dd69
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2009 (2024)
The core pathological event in Parkinson’s disease (PD) is the specific dying of dopamine (DA) neurons of the substantia nigra pars compacta (SNc). The reasons why SNc DA neurons are especially vulnerable and why idiopathic PD has only been found i
Externí odkaz:
https://doaj.org/article/6e957b6137ee437b854ea7c77eff60b9
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16797 (2023)
Superficial discolored spots on Atlantic salmon (Salmo salar) fillets are a serious quality problem for commercial seafood farming. Previous reports have proposed that the black spots (called melanized focal changes (MFCs)) may be melanin, but no con
Externí odkaz:
https://doaj.org/article/026b83c7fba64d6884851c10cd4d57ac
Autor:
Yujiao Sun, Lizhen Ma, Shen Li, Yawen Wang, Ruiqi Xiao, Junqi Yang, Johannes M. Dijkstra, Chun Xia
Publikováno v:
Cells, Vol 12, Iss 7, p 1097 (2023)
DLA-88 is a classical major histocompatibility complex (MHC) class I gene in dogs, and allelic DLA-88 molecules have been divided into two categories named “DLA-88*0” and “DLA-88*5.” The defining difference between the two categories concerns
Externí odkaz:
https://doaj.org/article/0a5881469d194e9abf35f7b9bbf926d5
Autor:
Tamae Ohye, Hiromu Takematsu, Johannes M. Dijkstra, Itsuro Katsuda, Hidehiko Akiyama, Taei Matsui, Atsushi Ogasawara, Yuki Higashimoto, Seiji Imamura, Hiroki Doi
Publikováno v:
F1000Research, Vol 10 (2022)
Background: Andrographolide (Andro) is a diterpenoid component of the plant Andrographis paniculata that is known for its anti-tumor activity against a variety of cancer cells. Methods: We studied the effects of Andro on the viability of the human le
Externí odkaz:
https://doaj.org/article/8e9d01f93fd94edc9397fc1cf7d4af83
Autor:
Tamae Ohye, Hiromu Takematsu, Johannes M. Dijkstra, Itsuro Katsuda, Hidehiko Akiyama, Taei Matsui, Atsushi Ogasawara, Yuki Higashimoto, Seiji Imamura, Hiroki Doi
Publikováno v:
F1000Research, Vol 10 (2021)
Background: Andrographolide (Andro) is a diterpenoid component of the plant Andrographis paniculata that is known for its anti-tumor activity against a variety of cancer cells. Methods: We studied the effects of Andro on the viability of the human le
Externí odkaz:
https://doaj.org/article/c33968b045ed473d9bdbfa000cca910c
Autor:
Johannes M. Dijkstra, Yasuto Kondo
Publikováno v:
Biology, Vol 11, Iss 12, p 1713 (2022)
Parvalbumins are small molecules with important functions in Ca2+ signaling, but their sequence comparisons to date, especially in fish, have been relatively poor. We here, characterize sequence motifs that distinguish parvalbumin subfamilies across
Externí odkaz:
https://doaj.org/article/0ee6e7c57f2c4589923ae7a534df1375
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Structures of peptide-loaded major histocompatibility complex class I (pMHC-I) and class II (pMHC-II) complexes are similar. However, whereas pMHC-II complexes include similar-sized IIα and IIβ chains, pMHC-I complexes include a heavy chain (HC) an
Externí odkaz:
https://doaj.org/article/502bfc837c8c4edcb15790eae1f30b29
Publikováno v:
F1000Research, Vol 10 (2021)
In the spring of 2020, we and others hypothesized that T cells in COVID-19 patients may recognize identical protein fragments shared between the coronaviruses of the common cold and COVID-19 and thereby confer cross-virus immune memory. Here, we look
Externí odkaz:
https://doaj.org/article/56f31ff99afd490e87dabbbe92a6bf27