Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Johannes Lerchner"'
Autor:
Marina R. Sartori, R. F. Castilho, Anibal E. Vercesi, Florian Mertens, Johannes Lerchner, Pedro L. O. Volpe
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 147:4611-4619
Ca2+ signaling in trypanosomatids is an important component of energy metabolism regulation and therefore, cytosolic Ca2+ concentration is finely regulated by Ca2+ transport through the plasma membrane and Ca2+ uptake and release by intracellular org
Autor:
M. Mazik, Florian Mertens, Johannes Lerchner, Marina R. Sartori, Anibal E. Vercesi, S. Förster, Pedro L. O. Volpe
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 147:2253-2263
The development of the segment-flow technology has considerably extended the application range of miniaturized calorimeters. The transport of samples in aqueous µL segments by a water-immiscible carrier liquid enables the investigation of aggregated
Autor:
Florian Mertens, Dulcineia M. Albuquerque, Pedro O. L. Volpe, Johannes Lerchner, Carolina Lanaro, Kleber Yotsumoto Fertrin, F. Haenschke, F. F. Costa
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 136:771-781
A new calorimetric technique is described which allows the measurement of metabolic heat rates in biological materials which are triggered by changes in the oxygen tension. It uses the high permeability for oxygen of a thin-walled Teflon flow channel
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 127:1307-1317
In the presented paper, the capability of segmented flow chip calorimeters for the analysis of time-dependent pharmaceutical effects on differently complex biological systems is demonstrated. Due to the noninvasive nature of calorimetric measurements
Autor:
Florian Mertens, Johannes Lerchner, Anibal E. Vercesi, Pedro O. L. Volpe, Marina R. Sartori, Noelia Lander
Publikováno v:
Analytical and bioanalytical chemistry. 411(17)
We describe a chip calorimetric technique that allows the investigation of biological material under anoxic conditions in a micro-scale and in real time. Due to the fast oxygen exchange through the sample flow channel wall, the oxygen concentration i
Autor:
K. Lemke, J. Schemberg, F. Hänschke, E. Kessler, A. Wolf, Tom Hartmann, Johannes Lerchner, Florian Mertens, T. Förster, A. Grodrian, Ralf Paus, Marta Bertolini
Publikováno v:
Thermochimica Acta. 603:172-183
The adaptation of segmented-flow technology to flow-through calorimetry was demonstrated by different kinds of newly designed chip calorimeters useful for liquids and suspensions as well as for solid samples. In segmented-flow technology, sample mate
Autor:
Florian Mertens, Nieves Barros, J. Schemberg, F. Hänschke, Pedro L. O. Volpe, A. Wolf, Christian Siewert, E. Kessler, Johannes Lerchner, Tom Hartmann, A. Grodrian
Publikováno v:
Sensors and Actuators B: Chemical. 201:460-468
We present the first silicon chip-based calorimeter with segmented-flow technology (SFT) for the study of solid and aggregated samples. Solid particles or biological aggregates up to 1.5 mm are immersed in segments of aqueous solutions. The segments
Autor:
Tom Hartmann, Thomas Maskow, Bärbel Kiesel, Frida Mariana Morais, Thomas R. Neu, Hauke Harms, Friederike Buchholz, Johannes Lerchner
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 115:2203-2210
Bacteriophages or phage-derived biological structures are a promising alternative to the application of antibiotics to eradicate biofilms. These countermeasures are highly cell specific. For a better understanding of the sequence of the underlying pr
Autor:
H.-J. Schneider, Thomas Maskow, Jochen Büchs, Lars Regestein, Johannes Lerchner, Florian Mertens, A. Wolf
Publikováno v:
Thermochimica Acta. 544:10-16
In conventional bioreactors, the assessment of metabolic heat via heat balancing is difficult. The reason is the influence of inherent variables such as power input due to stirring, environmental heat loss and evaporation. Thus, the aim of this study
Autor:
Theresa Poeschel, Florian Mertens, Anne Schulz, Johannes Lerchner, A. Wolf, Elke Boschke, Tom Hartmann
Publikováno v:
Engineering in Life Sciences. 12:615-620
Microcalorimetryisananalyticaltoolthatallowsthedirectmea-surementofheatgeneratedbybiologicalprocessesinlivingcells.Due to its high sensitivity, accuracy, and simplicity, the methodhas been widely employed in biology, microbiology, pharma-cology,biote