Zobrazeno 1 - 10
of 1 285
pro vyhledávání: '"Johannes Kornhuber"'
Autor:
Maximilian Bailer, Eva M. Stein, Maximilian I. Sprügel, Stefan Mestermann, Philipp Spitzer, Janine Utz, Sabine Zirlik, Florian S. Fuchs, Johannes Kornhuber
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Symptoms of obstructive sleep apnoea (OSA) overlap significantly with those of psychiatric disorders, making accurate diagnosis of OSA challenging within psychiatric settings. Diagnosing OSA in psychiatric patients is crucial beca
Externí odkaz:
https://doaj.org/article/ab39208092ef4d7abfaad7c7853645c1
Autor:
Miriam Rabl, Leonardo Zullo, Piotr Lewczuk, Johannes Kornhuber, Thomas K. Karikari, Kaj Blennow, Henrik Zetterberg, Francesco Bavato, Boris B. Quednow, Erich Seifritz, Armin von Gunten, Christopher Clark, Julius Popp
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Neuropsychiatric symptoms (NPS) are common in older people, may occur early in the development of dementia disorders, and have been associated with faster cognitive decline. Here, our objectives were to investigate whether plasma
Externí odkaz:
https://doaj.org/article/0f38378ecba046c399aaa3cc26c9200c
Autor:
Franziska Albrecht, Karsten Mueller, Tommaso Ballarini, Klaus Fassbender, Jens Wiltfang, Markus Otto, Robert Jech, Mattias L. Schroeter, Adrian Danek, Janine Diehl-Schmid, Holger Jahn, Jan Kassubek, Johannes Kornhuber, Bernhard Landwehrmeyer, Martin Lauer, Johannes Prudlo, Anja Schneider, Albert C. Ludolph, Klaus Fliesbach, Sarah Anderl-Straub, Katharina Brüggen, Marie Fischer, Hans Förstl, Anke Hammer, György Homola, Walter Just, Johannes Levin, Nicolai Marroquin, Anke Marschhauser, Danielé Pino, Magdalena Nagl, Timo Oberstein, Lea Hüper, Maryna Polyakova, Hannah Pellkofer, Tanja Richter-Schmidinger, Carola Rossmeier, Marianna Kulko, Elisa Semler, Annika Spottke, Petra Steinacker, Angelika Thöne-Otto, Ingo Uttner, Heike Zech
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34910- (2024)
Progressive supranuclear palsy (PSP) is an atypical Parkinsonian syndrome characterized initially by falls and eye movement impairment. This multimodal imaging study aimed at eliciting structural and functional disease-specific brain alterations. T1-
Externí odkaz:
https://doaj.org/article/512938e68e87433097744a778848f048
Autor:
Joanna Kamińska, Marzena Tylicka, Kinga Sutkowska, Karolina Marta Gacuta, Magdalena Maria Sawicka, Ewa Kowalewska, Magdalena Ćwiklińska-Dworakowska, Mateusz Maciejczyk, Tomasz Łysoń, Johannes Kornhuber, Piotr Lewczuk, Joanna Matowicka-Karna, Olga Martyna Koper-Lenkiewicz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The significant role of increased activation of 20S proteasomes in the development of abdominal aortic aneurysms has been well-established in a mouse model. The available literature lacks similar studies concerning brain aneurysms. The aim o
Externí odkaz:
https://doaj.org/article/1dd7656346334efdb9736f8275e8f91d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8685 (2024)
Accumulating evidence suggests an involvement of sphingolipids, vital components of cell membranes and regulators of cellular processes, in the pathophysiology of both Parkinson’s disease and major depressive disorder, indicating a potential common
Externí odkaz:
https://doaj.org/article/3289072212d1488594ccbe02b860a017
Autor:
Lara Blömeke, Fabian Rehn, Victoria Kraemer‐Schulien, Janine Kutzsche, Marlene Pils, Tuyen Bujnicki, Piotr Lewczuk, Johannes Kornhuber, Silka D. Freiesleben, Luisa‐Sophie Schneider, Lukas Preis, Josef Priller, Eike J. Spruth, Slawek Altenstein, Andrea Lohse, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Niels Hansen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I. Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris‐Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Carolin Sanzenbacher, Annika Spottke, Nina Roy‐Kluth, Michael T. Heneka, Frederic Brosseron, Michael Wagner, Steffen Wolfsgruber, Luca Kleineidam, Melina Stark, Matthias Schmid, Frank Jessen, Oliver Bannach, Dieter Willbold, Oliver Peters
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION Soluble amyloid beta (Aβ) oligomers have been suggested as initiating Aβ related neuropathologic change in Alzheimer's disease (AD) but their quantitative distribution and chronological sequence within the AD continuum remain
Externí odkaz:
https://doaj.org/article/4bb37b34bcf7452db948167c1f2af3cc
Autor:
Monique L. Mefrouche, Eva-Maria Siegmann, Stephanie Böhme, Matthias Berking, Johannes Kornhuber
Publikováno v:
European Journal of Investigation in Health, Psychology and Education, Vol 13, Iss 9, Pp 1694-1706 (2023)
Introduction. Pregnancy is a unique time in a woman’s life that can be both exciting and challenging. It is also a period that can be associated with significant stress, anxiety, and depression, which can have negative consequences for both the mot
Externí odkaz:
https://doaj.org/article/6bc40dbff31c439488ffbb36dba8cd2b
Autor:
Leona Kind, Katharina Luttenberger, Vivien Leßmann, Lisa Dorscht, Christiane Mühle, Christian P. Müller, Eva-Maria Siegmann, Sophia Schneider, Johannes Kornhuber
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Due to the growing gap between the demand and supply of therapeutic services for people suffering from depression, with this study, we are investigating the effectiveness and factors of influence of new approaches in group treatme
Externí odkaz:
https://doaj.org/article/ec09c208a8304fc8bebb1acc22dc79e9
Autor:
Lisa Hahn, Simon B Eickhoff, Karsten Mueller, Leonhard Schilbach, Henryk Barthel, Klaus Fassbender, Klaus Fliessbach, Johannes Kornhuber, Johannes Prudlo, Matthis Synofzik, Jens Wiltfang, Janine Diehl-Schmid, FTLD Consortium, Markus Otto, Juergen Dukart, Matthias L Schroeter
Publikováno v:
eLife, Vol 13 (2024)
Background: Aside to clinical changes, behavioral variant frontotemporal dementia (bvFTD) is characterized by progressive structural and functional alterations in frontal and temporal regions. We examined if there is a selective vulnerability of spec
Externí odkaz:
https://doaj.org/article/fde05e0927944a91a3fee2d7e54c5bed
Autor:
Byung Jo Choi, Min Hee Park, Kang Ho Park, Wan Hui Han, Hee Ji Yoon, Hye Yoon Jung, Ju Yeon Hong, Md Riad Chowdhury, Kyung Yeol Kim, Jihoon Lee, Im-Sook Song, Minyeong Pang, Min-Koo Choi, Erich Gulbins, Martin Reichel, Johannes Kornhuber, Chang-Won Hong, Changho Kim, Seung Hyun Kim, Edward H. Schuchman, Hee Kyung Jin, Jae-sung Bae
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Acid sphingomyelinase (ASM) is a sphingolipid metabolizing enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide, and previous work has shown it is upregulated in models of Alzheimer’s disease. Here the authors demonstrate in a mouse mo
Externí odkaz:
https://doaj.org/article/52c99cf51ae64f39b52ec19ee7f53cf4