Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Johannes Konietzko"'
Publikováno v:
International Archives of Occupational and Environmental Health. 74:43-48
Objectives: Even low concentrations of organic solvents may cause acute effects on the human central nervous system. The German MAK (threshold limit value) of methanol is 200 ppm. The aim of this study was to investigate whether acute exposure to 200
Publikováno v:
International Archives of Occupational and Environmental Health. 72:485-488
Objectives: Irritating effects of organic solvents have usually been measured by means of questionnaires. The aim of the present study was to evaluate the sensitivity of different methods of detecting subclinical irritating effects. Methods: Twelve h
Publikováno v:
International Archives of Occupational and Environmental Health. 70:407-412
Objectives: To evaluate the effects of low concentrations of organic solvents on color vision. Methods: Color vision was examined in 24 workers exposed to mixtures of solvents and in 24 control subjects. Exposure to mixtures was below the threshold-l
Publikováno v:
Europe PubMed Central
In 91 nurses from several divisions of four hospitals in Germany the genotoxic effect caused by the occupational exposure presumably due to mixing of antineoplastic agents was investigated. The amount of DNA single strand breaks and alkali labile sit
Autor:
Axel Muttray, Johannes Konietzko, Herbert Josef Zimmermann-Hölz, Manfred Doss, Annette Kopp-Schneider, Hans Beck, Gertraud Reill-Konietzko, Detlev Jung, Lutz Edler
Publikováno v:
Archives of Toxicology. 68:595-598
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been shown to inhibit uroporphyrinogen decarboxylase activity resulting in chronic hepatic porphyria. From a cross-sectional study of 170 workers in chemical industry 68 showed elevated coproporphyrin le
Publikováno v:
Chemosphere. 25:1021-1027
To assess the exposure to PCDD/Fs of a cohort of 1583 workers of a herbicide producing plant in Hamburg, FRG, investigated for cancer mortality, measurements of PCDD/Fs in fat tissue (n=48) or blood (n=64) were analyzed according to work histories in
Publikováno v:
American journal of rhinology. 18(2)
Background Animal experiments indicate that 1,1,1-trichloroethane can cause degeneration of the olfactory epithelium. The effects of 1,1,1-trichloroethane on human odor perception still have not been investigated. The goal of this study was to learn
Publikováno v:
Neurotoxicology and teratology. 21(1)
High exposure to toluene may cause optic neuropathy and retinopathy, both associated with dyschromatopsia. Another solvent, ethanol, is known to induce acute blue-yellow dyschromatopsia. This study investigated the acute effects of high doses of tolu
Autor:
Heiko Becher, Gurn P, Dieter Flesch-Janys, Detlev Jung, Alfred Manz, L. Edler, Johannes Konietzko, Olaf Päpke
Publikováno v:
Journal of toxicology and environmental health. 51(1)
The elimination of beta-hexachlorocyclohexane (beta-HCH) in humans was investigated in a group of 40 former workers of a lindane-producing plant by analyzing at least 2 blood specimens (3 specimens in 3 workers) from different time points. Assuming a
Elimination of polychlorinated dibenzo-p-dioxins and dibenzofurans in occupationally exposed persons
Autor:
Detlev Jung, Alfred Manz, Dieter Flesch-Janys, Gurn P, Johannes Konietzko, Heiko Becher, Olaf Päpke
Publikováno v:
Journal of toxicology and environmental health. 47(4)
The elimination of 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F) was investigated in a group of n = 43 exposed workers with 2 blood measurements and n = 5 workers with 3 measurements. Under the assumption of a one-c