Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Johannes Klopf"'
Autor:
Johannes Klopf, Branislav Zagrapan, Annika Brandau, Peter Lechenauer, Catharina J. Candussi, Patrick Rossi, Nihan Dide Celem, Michael Ziegler, Lukas Fuchs, Hubert Hayden, Claus G. Krenn, Wolf Eilenberg, Christoph Neumayer, Christine Brostjan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAbdominal aortic aneurysm (AAA) development is driven by inflammation, in particular myeloid cells, which represent attractive biomarker candidates. Yet to date, the maximum aortic diameter is the only clinically applied predictor of AAA pr
Externí odkaz:
https://doaj.org/article/7a5eb83288c746d8bc1e0c22250523e0
Autor:
Nahla Ibrahim, Sonja Bleichert, Johannes Klopf, Gabriel Kurzreiter, Viktoria Knöbl, Hubert Hayden, Albert Busch, Alexander Stiglbauer-Tscholakoff, Wolf Eilenberg, Christoph Neumayer, Marc A. Bailey, Christine Brostjan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundAvailable mouse models for abdominal aortic aneurysms (AAAs) differ substantially in the applied triggers, associated pathomechanisms and rate of vessel expansion. While maximum aortic diameter (determined after aneurysm excision or by 2D u
Externí odkaz:
https://doaj.org/article/26b8b24a14f747bdbb96cda604e3144a
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1317 (2023)
Complex endovascular aortic repair (coEVAR) of thoracoabdominal aortic aneurysms (TAAA) has greatly evolved in the past decades. Despite substantial improvements of postoperative care, spinal cord injury (SCI) remains the most devastating complicatio
Externí odkaz:
https://doaj.org/article/508e62d9609049d88403ed5ccf7cde10
Autor:
Hubert Hayden, Nahla Ibrahim, Johannes Klopf, Branislav Zagrapan, Lisa-Marie Mauracher, Lena Hell, Thomas M Hofbauer, Anna S Ondracek, Christian Schoergenhofer, Bernd Jilma, Irene M Lang, Ingrid Pabinger, Wolf Eilenberg, Christoph Neumayer, Christine Brostjan
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250265 (2021)
Over the past years, neutrophil extracellular traps (NETs) were shown to contribute to states of acute and chronic inflammatory disease. They are composed of expelled chromatin and decorated by neutrophil-derived proteins. Therefore, the analysis of
Externí odkaz:
https://doaj.org/article/5d7c94b238514368ac40a50a22619a5d
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 94 (2022)
Despite declining incidence and mortality rates in many countries, the abdominal aortic aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an overall prevalence of about 2–3% in the industrialized world. While th
Externí odkaz:
https://doaj.org/article/f96cb628d12e4e2fbb8d870e34248d16
Autor:
Annika Brandau, Nahla Ibrahim, Johannes Klopf, Hubert Hayden, Maria Ozsvar-Kozma, Taras Afonyushkin, Sonja Bleichert, Lukas Fuchs, Viktoria Watzinger, Verena Nairz, Emely Manville, Veronika Kessler, Herbert Stangl, Wolf Eilenberg, Christoph Neumayer, Christine Brostjan
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 217 (2022)
Neutrophil extracellular traps (NETs) are DNA–protein structures released by neutrophils in response to various stimuli, including oxidized, low-density lipoprotein (oxLDL). Accumulating evidence suggests a role for NETs in the pathogenesis of abdo
Externí odkaz:
https://doaj.org/article/12ec5566ec4d4135ae58854e402ffa0e
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1236 (2021)
Neutrophils represent up to 70% of circulating leukocytes in healthy humans and combat infection mostly by phagocytosis, degranulation and NETosis. It has been reported that neutrophils are centrally involved in abdominal aortic aneurysm (AAA) pathog
Externí odkaz:
https://doaj.org/article/96929ed18b934e7a9740df798d54006f
Autor:
Johannes Klopf, Lukas Fuchs, Rüdiger Schernthaner, Christoph M. Domenig, Bernd Gollackner, Christine Brostjan, Christoph Neumayer, Wolf Eilenberg
Publikováno v:
Journal of Vascular Surgery. 75:1926-1934
The maximal aortic diameter is currently the only clinically applied predictor of abdominal aortic aneurysm (AAA) progression. It is known that the risk of rupture is associated with aneurysm size; hence, accurate monitoring of AAA expansion is cruci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a31940c635da0abe1ad9e2d35e3f78
https://doi.org/10.1016/j.jvs.2021.11.062
https://doi.org/10.1016/j.jvs.2021.11.062
Autor:
Paimann Nawrozi, Marc A. Bailey, Johannes Klopf, Christoph Neumayer, Lisa-Marie Mauracher, Nawa Schirwani, Viktoria Knöbl, Peter Teubenbacher, Alexander Stiglbauer-Tscholakoff, Irene Lang, Albert Busch, Lars Maegdefessel, Hubert Hayden, Ingrid Pabinger, Sonja Bleichert, Lena Hell, Adelheid Panzenböck, Alexandros Potolidis, Charlotte Häusler, Luca Martelanz, Markus P. Weigl, Branislav Zagrapan, Christine Brostjan, Nahla Ibrahim, Andreas Scheuba, Wolf Eilenberg, Annika Brandau, Patrick Kirchweger, Renata Rajic, D Julian A Scott, Dietrich Beitzke, Ihor Huk, Marie-Therese Grasl
Publikováno v:
Translational Research. 233:32-46
Neutrophil extracellular traps (NETs) have been implicated in the pathogenesis of abdominal aortic aneurysms (AAAs). This study has addressed the notion that NET components might serve as AAA biomarkers or novel targets of AAA therapy. Thus, paramete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292aaa40fe40fd739f86d9d6aa338f2b
https://doi.org/10.1016/j.trsl.2021.02.003
https://doi.org/10.1016/j.trsl.2021.02.003
Autor:
Johannes Klopf, Svitlana Demyanets, Mira Brekalo, Wolf Eilenberg, Johann Wojta, Christoph Neumayer, Christine Brostjan, Stefan Stojkovic
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9598
The maximal aortic diameter is the only clinically applied predictor of abdominal aortic aneurysm (AAA) progression and indicator for surgical repair. Circulating biomarkers resulting from AAA pathogenesis are attractive candidates for the diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9b3d2a239935a08a596df93276348d
https://pubmed.ncbi.nlm.nih.gov/36076997
https://pubmed.ncbi.nlm.nih.gov/36076997