Structural Covariance Networks in the Fetal Brain Reveal Altered Neurodevelopment for Specific Subtypes of Congenital Heart Disease

Autor: Siân Wilson, Daniel Cromb, Alexandra F. Bonthrone, Alena Uus, Anthony Price, Alexia Egloff, Milou P. M. Van Poppel, Johannes K. Steinweg, Kuberan Pushparajah, John Simpson, David F. A. Lloyd, Reza Razavi, Jonathan O'Muircheartaigh, A. David Edwards, Joseph V. Hajnal, Mary Rutherford, Serena J. Counsell

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)

Background Altered structural brain development has been identified in fetuses with congenital heart disease (CHD), suggesting that the neurodevelopmental impairment observed later in life might originate in utero. There are many interacting factors

Externí odkaz: https://doaj.org/article/0ad6a104a7b54316875c9a8b576d76d6

3D black blood cardiovascular magnetic resonance atlases of congenital aortic arch anomalies and the normal fetal heart: application to automated multi-label segmentation

Autor: Alena U. Uus, Milou P. M. van Poppel, Johannes K. Steinweg, Irina Grigorescu, Paula Ramirez Gilliland, Thomas A. Roberts, Alexia Egloff Collado, Mary A. Rutherford, Joseph V. Hajnal, David F. A. Lloyd, Kuberan Pushparajah, Maria Deprez

Publikováno v: Journal of Cardiovascular Magnetic Resonance, Vol 24, Iss 1, Pp 1-13 (2022)

Abstract Background Image-domain motion correction of black-blood contrast T2-weighted fetal cardiovascular magnetic resonance imaging (CMR) using slice-to-volume registration (SVR) provides high-resolution three-dimensional (3D) images of the fetal

Externí odkaz: https://doaj.org/article/a0f10f06be4042fb8d4ba0bc926ca790

Structured analysis of the impact of fetal motion on phase-contrast MRI flow measurements with metric optimized gating

Autor: Alexander Schulz, David F. A. Lloyd, Milou P. M. van Poppel, Thomas A. Roberts, Johannes K. Steinweg, Kuberan Pushparajah, Joseph V. Hajnal, Reza Razavi

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract The impact of fetal motion on phase contrast magnetic resonance imaging (PC-MRI) with metric optimized gating (MOG) remains unknown, despite being a known limitation to prenatal MRI. This study aims to describe the effect of motion on fetal

Externí odkaz: https://doaj.org/article/89cb5f11c21240a18954dfce5e80a7f1

Learning the Hidden Signature of Fetal Arch Anatomy: a Three-Dimensional Shape Analysis in Suspected Coarctation of the Aorta

Autor: Uxio Hermida, Milou P. M. van Poppel, David F. A. Lloyd, Johannes K. Steinweg, Trisha V. Vigneswaran, John M. Simpson, Reza Razavi, Adelaide De Vecchi, Kuberan Pushparajah, Pablo Lamata

Publikováno v: Journal of Cardiovascular Translational Research.

Neonatal coarctation of the aorta (CoA) is a common congenital heart defect. Its antenatal diagnosis remains challenging, and its pathophysiology is poorly understood. We present a novel statistical shape modeling (SSM) pipeline to study the role and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7d0dc745c763f6ec31c87cc41357ffb
https://doi.org/10.1007/s12265-022-10335-9

Phenotyping the Preterm Brain: Characterizing Individual Deviations From Normative Volumetric Development in Two Large Infant Cohorts

Autor: Sophie Arulkumaran, Emer Hughes, Shona Falconer, Emma C. Robinson, Andrew Chew, Teixeira Rpag., Daniel Rueckert, Johannes K. Steinweg, Olivia Carney, Andreas Schuh, Dafnis Batalle, Joseph V. Hajnal, Serena J. Counsell, Judit Ciarrusta, Mary A. Rutherford, Grainne M. McAlonan, Ralica Dimitrova, Jonathan O'Muircheartaigh, Katy Vecchiato, Alexander D. Edwards, Russell Macleod, Jana Hutter, Stephen M. Smith, Alexia Egloff, Andre F. Marquand, Thomas Wolfers, Lucilio Cordero-Grande, Anthony N. Price, Antonios Makropoulos

Publikováno v: Cerebral Cortex (New York, NY)
Dimitrova, R, Arulkumaran, S, Carney, O, Chew, A, Falconer, S, Ciarrusta, J, Wolfers, T, Batalle, D, Cordero-Grande, L, Price, A N, Teixeira, R P A G, Hughes, E, Egloff, A, Hutter, J, Makropoulos, A, Robinson, E C, Schuh, A, Vecchiato, K, Steinweg, J K, Macleod, R, Marquand, A F, McAlonan, G, Rutherford, M A, Counsell, S J, Smith, S M, Rueckert, D, Hajnal, J V, O'Muircheartaigh, J & Edwards, A D 2021, ' Phenotyping the Preterm Brain : Characterizing Individual Deviations from Normative Volumetric Development in Two Large Infant Cohorts ', Cerebral Cortex, vol. 31, no. 8, pp. 3665-3677 . https://doi.org/10.1093/cercor/bhab039

The diverse cerebral consequences of preterm birth create significant challenges for understanding pathogenesis or predicting later outcome. Instead of focusing on describing effects common to the group, comparing individual infants against robust no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9288ab0415f0dd6c83986dcb37654b1d
http://europepmc.org/articles/PMC8258435