Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Johannes J. Fels"'
Autor:
Birgitte S. Wulff, Rune Ehrenreich Kuhre, Madhan Selvaraj, Jens F. Rehfeld, Kristoffer Niss, Johannes J. Fels, Secher Anna, Kirsten Raun, Marina Kjaergaard Gerstenberg
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32009- (2024)
Objective: Co-treatment with long acting PYY and the GLP-1 receptor agonists has potential as an efficient obesity treatment. This study investigates whether the mechanisms behind additive reduction of food intake and weight loss depends on complemen
Externí odkaz:
https://doaj.org/article/4c1a17d3a0794a50bafbe1ca28b42027
Autor:
Vivi F. H. Jensen, Anne-Marie Mølck, Jette Nowak, Johannes J. Fels, Jens Lykkesfeldt, Ingrid B. Bøgh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Pancreatic β-cells have an extraordinary ability to adapt to acute fluctuations in glucose levels by rapid changing insulin production to meet metabolic needs. Although acute changes have been characterised, effects of prolonged metabolic s
Externí odkaz:
https://doaj.org/article/e3de2ad81ff644939436faa21a79b44b
Autor:
Shailesh Kumar Gupta, Agata Wesolowska-Andersen, Anna K. Ringgaard, Himjyot Jaiswal, Luyan Song, Benoit Hastoy, Camilla Ingvorsen, Amir Taheri-Ghahfarokhi, Björn Magnusson, Marcello Maresca, Rikke R. Jensen, Nicola L. Beer, Johannes J. Fels, Lars G. Grunnet, Melissa K. Thomas, Anna L. Gloyn, Ryan Hicks, Mark I. McCarthy, Mattias Hansson, Christian Honoré
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 220-231 (2018)
Recent studies have reported significant advances in the differentiation of human pluripotent stem cells to clinically relevant cell types such as the insulin producing beta-like cells and motor neurons. However, many of the current differentiation p
Externí odkaz:
https://doaj.org/article/388e243f0c3f452f8d7167f3e381a0f1
Autor:
Petr, Zouhar, Günaj, Rakipovski, Muhammad Hamza, Bokhari, Oliver, Busby, Johan F, Paulsson, Kilian W, Conde-Frieboes, Johannes J, Fels, Kirsten, Raun, Birgitte, Andersen, Barbara, Cannon, Jan, Nedergaard
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism
The possibility to use leptin therapeutically for lowering glucose levels in patients with type 1 diabetes has attracted interest. However, earlier animal models of type 1 diabetes are severely catabolic with very low endogenous leptin levels, unlike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63eabe2f880be82adf1e7bb2d9cc7e8d
https://pubmed.ncbi.nlm.nih.gov/31743040
https://pubmed.ncbi.nlm.nih.gov/31743040
Autor:
Abramson A; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Chemical Engineering, Stanford University, Stanford, CA, USA., Frederiksen MR; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark.; Orbex Denmark, Copenhagen, Denmark., Vegge A; Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark., Jensen B; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Poulsen M; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Mouridsen B; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Jespersen MO; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Kirk RK; Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark., Windum J; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Hubálek F; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Water JJ; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Fels J; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Gunnarsson SB; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Bohr A; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Straarup EM; Global Drug Discovery, Novo Nordisk A/S, Maaloev, Denmark., Ley MWH; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Lu X; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Wainer J; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Fractyl Health Inc., Lexington, MA, USA., Collins J; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Tamang S; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Ishida K; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Hayward A; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Herskind P; Devices and Delivery Solutions, Novo Nordisk A/S, Hilleroed, Denmark., Buckley ST; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Roxhed N; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden., Langer R; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA., Rahbek U; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark. ulyr@novonordisk.com., Traverso G; Department of Chemical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. cgt20@mit.edu.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. cgt20@mit.edu.; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. cgt20@mit.edu.
Publikováno v:
Nature biotechnology [Nat Biotechnol] 2022 Jan; Vol. 40 (1), pp. 103-109. Date of Electronic Publication: 2021 Aug 30.
Autor:
Probst S; Faculty of Health, Institute of Physiology, Pathophysiology and Toxicology and ZBAF (Centre for Biomedical Education and Research), School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany., Fels J; Faculty of Health, Institute of Physiology, Pathophysiology and Toxicology and ZBAF (Centre for Biomedical Education and Research), School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany., Scharner B; Faculty of Health, Institute of Physiology, Pathophysiology and Toxicology and ZBAF (Centre for Biomedical Education and Research), School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany., Wolff NA; Faculty of Health, Institute of Physiology, Pathophysiology and Toxicology and ZBAF (Centre for Biomedical Education and Research), School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany., Roussa E; Department of Molecular Embryology, Faculty of Medicine, Institute of Anatomy and Cell Biology, University of Freiburg, Albertstr. 17, 79104, Freiburg, Germany., van Swelm RPL; Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, The Netherlands., Lee WK; Faculty of Health, Institute of Physiology, Pathophysiology and Toxicology and ZBAF (Centre for Biomedical Education and Research), School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany.; AG Physiology and Pathophysiology of Cells and Membranes, Medical School OWL, Bielefeld University, Morgenbreede 1, 33615, Bielefeld, Germany., Thévenod F; Faculty of Health, Institute of Physiology, Pathophysiology and Toxicology and ZBAF (Centre for Biomedical Education and Research), School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany. frank.thevenod@uni-wh.de.
Publikováno v:
Archives of toxicology [Arch Toxicol] 2021 Aug; Vol. 95 (8), pp. 2719-2735. Date of Electronic Publication: 2021 Jun 28.
Autor:
Caffarel-Salvador E; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Kim S; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Soares V; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Tian RY; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Stern SR; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Minahan D; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Yona R; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Lu X; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Zakaria FR; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Collins J; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Wainer J; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Wong J; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., McManus R; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Tamang S; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., McDonnell S; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Ishida K; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Hayward A; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Liu X; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH, UK., Hubálek F; Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark., Fels J; Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark., Vegge A; Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark., Frederiksen MR; Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark., Rahbek U; Global Research Technologies, Global Drug Discovery, and Device R&D, Novo Nordisk A/S, Måløv, Denmark., Yoshitake T; Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Fujimoto J; Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Roxhed N; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; School of Electrical Engineering and Computer Science, Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden., Langer R; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. rlanger@mit.edu cgt20@mit.edu.; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Traverso G; Department of Chemical Engineering and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. rlanger@mit.edu cgt20@mit.edu.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Publikováno v:
Science advances [Sci Adv] 2021 Jan 22; Vol. 7 (4). Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).
Autor:
Mewes M; Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, University Hospital Muenster, Muenster, Germany., Lenders M; Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, University Hospital Muenster, Muenster, Germany., Stappers F; Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, University Hospital Muenster, Muenster, Germany., Scharnetzki D; Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, University Hospital Muenster, Muenster, Germany., Nedele J; Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, University Hospital Muenster, Muenster, Germany., Fels J; Institute for Cell Dynamics and Imaging, Medical Faculty, University of Muenster, Muenster, Germany.; Department of Physiology, Pathophysiology and Toxicology and Center for Biomedical Education and Research (ZBAF), University of Witten/Herdecke, Witten, Germany., Wedlich-Söldner R; Institute for Cell Dynamics and Imaging, Medical Faculty, University of Muenster, Muenster, Germany., Brand SM; Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany., Schmitz B; Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany., Brand E; Internal Medicine D, Department of Nephrology, Hypertension, and Rheumatology, University Hospital Muenster, Muenster, Germany.
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Dec; Vol. 33 (12), pp. 13762-13774. Date of Electronic Publication: 2019 Oct 04.
Autor:
Abramson A; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Caffarel-Salvador E; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Soares V; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Minahan D; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Tian RY; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Lu X; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Dellal D; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA., Gao Y; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Kim S; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Wainer J; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Collins J; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Tamang S; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Hayward A; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA., Yoshitake T; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA., Lee HC; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA., Fujimoto J; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA, USA., Fels J; Global Research Technologies, Global Drug Discovery, Måløv, Denmark.; Device R&D, Novo Nordisk, Måløv, Denmark., Frederiksen MR; Global Research Technologies, Global Drug Discovery, Måløv, Denmark.; Device R&D, Novo Nordisk, Måløv, Denmark., Rahbek U; Global Research Technologies, Global Drug Discovery, Måløv, Denmark.; Device R&D, Novo Nordisk, Måløv, Denmark., Roxhed N; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Micro and Nanosystems, KTH Royal Institute of Technology, Stockholm, Sweden., Langer R; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. rlanger@mit.edu.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. rlanger@mit.edu.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA. rlanger@mit.edu.; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. rlanger@mit.edu.; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA. rlanger@mit.edu., Traverso G; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. cgt20@mit.edu.; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. cgt20@mit.edu.; Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. cgt20@mit.edu.; Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. cgt20@mit.edu.
Publikováno v:
Nature medicine [Nat Med] 2019 Oct; Vol. 25 (10), pp. 1512-1518. Date of Electronic Publication: 2019 Oct 07.
Autor:
Thévenod F; Department of Physiology, Pathophysiology & Toxicology and ZBAF (Centre for Biomedical Education and Research), Faculty of Health, School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany. frank.thevenod@uni-wh.de., Fels J; Department of Physiology, Pathophysiology & Toxicology and ZBAF (Centre for Biomedical Education and Research), Faculty of Health, School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany., Lee WK; Department of Physiology, Pathophysiology & Toxicology and ZBAF (Centre for Biomedical Education and Research), Faculty of Health, School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany., Zarbock R; Department of Physiology, Pathophysiology & Toxicology and ZBAF (Centre for Biomedical Education and Research), Faculty of Health, School of Medicine, Witten/Herdecke University, Stockumer Str 12 (Thyssenhaus), 58453, Witten, Germany.
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine [Biometals] 2019 Jun; Vol. 32 (3), pp. 469-489. Date of Electronic Publication: 2019 Jan 30.