Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray

Autor: Rafael R. de Assis, Aarti Jain, Rie Nakajima, Algis Jasinskas, Jiin Felgner, Joshua M. Obiero, Philip J. Norris, Mars Stone, Graham Simmons, Anil Bagri, Johannes Irsch, Martin Schreiber, Andreas Buser, Andreas Holbro, Manuel Battegay, Philip Hosimer, Charles Noesen, Oluwasanmi Adenaiye, Sheldon Tai, Filbert Hong, Donald K. Milton, D. Huw Davies, Paul Contestable, Laurence M. Corash, Michael P. Busch, Philip L. Felgner, Saahir Khan

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)

COVID-19 diagnosis is commonly performed by PCR testing, however, serologic methods are more accurate and versatile for monitoring disease burden and epidemiology. Here the authors report a protein microarray with antigens from SARS-CoV-2, SARS-CoV,

Externí odkaz: https://doaj.org/article/307aa88ea3a740b187cbbb0355b0645c

In response to Focosi and Casadevall

Autor: Anil Bagri, Johannes Irsch, Laurence Corash

Publikováno v: Transfusion. 62(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdb871523ee61c02cff544b6b6b08a0
https://pubmed.ncbi.nlm.nih.gov/35932390

Pathogen inactivation with amotosalen plus UVA illumination minimally impacts microRNA expression in platelets during storage under standard blood banking conditions

Autor: Ottar Rolfsson, Johannes Irsch, Olafur E. Sigurjonsson, Niels Arni Arnason, Björn Hardarsson, Sveinn Vidar Gudmundsson, Ragna Landrö, Freyr Johannson

Publikováno v: Transfusion. 59:3727-3735

Background To reduce the risk of transfusion transmission infection, nucleic acid targeted methods have been developed to inactivate pathogens in PCs. miRNAs have been shown to play an important role in platelet function, and changes in the abundance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c0e465952e7e0db35ad0bc84c2d38d
https://doi.org/10.1111/trf.15575

Is pathogen reduction an acceptable alternative to irradiation for risk mitigation of transfusion-associated graft versus host disease?

Autor: Marissa, Li, Johannes, Irsch, Laurence, Corash, Richard J, Benjamin

Publikováno v: Transfusion and Apheresis Science. 61:103404

Transfusion-associated graft versus host disease (TA-GVHD) is a highly morbid and often fatal adverse event associated with transfusion of cellular blood products [platelets, red blood cells (RBCs) and whole blood] and more rarely with never-frozen p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00855c344c8870a8064eff1b76439ec4
https://doi.org/10.1016/j.transci.2022.103404

Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Blood using a Coronavirus Antigen Microarray

Autor: Jiin Felgner, Martin A. Schreiber, Oluwasanmi Adenaiye, Rafael Ramiro de Assis, Johannes Irsch, Donald K. Milton, D. Huw Davies, Algis Jasinskas, Philip Hosimer, Rie Nakajima, Anil Bagri, S.-H. Sheldon Tai, Philip L. Felgner, Philip J. Norris, Aarti Jain, Filbert Hong, Paul B. Contestable, Graham Simmons, Andreas Holbro, Michael P. Busch, Charles Noesen, Laurence Corash, Andreas Buser, Mars Stone, Joshua M. Obiero, Manuel Battegay, Saahir Khan

Publikováno v: Nature Communications
bioRxiv
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, vol 12, iss 1

The current practice for diagnosis of COVID-19, based on SARS-CoV-2 PCR testing of pharyngeal or respiratory specimens in a symptomatic patient at high epidemiologic risk, likely underestimates the true prevalence of infection. Serologic methods can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf4d0725e2018b8de832287c31b5e4e
https://doi.org/10.1101/2020.04.15.043364