Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Johannes Harder"'
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-12 (2021)
Abstract Background The alcohol 2,3-butanediol (2,3-BDO) is an important chemical and an Escherichia coli producer strain was recently engineered for bio-based production of 2,3-BDO. However, further improvements are required for realistic applicatio
Externí odkaz:
https://doaj.org/article/8354fa63227a454eb9435eb056954652
Publikováno v:
Microbial Cell Factories
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-12 (2021)
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-12 (2021)
Background The alcohol 2,3-butanediol (2,3-BDO) is an important chemical and an Escherichia coli producer strain was recently engineered for bio-based production of 2,3-BDO. However, further improvements are required for realistic applications. Resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95c6ca949ac6a5179de6cca598ed7f9
https://pubmed.ncbi.nlm.nih.gov/33750397
https://pubmed.ncbi.nlm.nih.gov/33750397
Additional file 1. Results of microaerobic cultivations; Strains, plasmids and primers used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7de66026cacb32e47ce61902013b78
Publikováno v:
Biospektrum
A key principle for the rational design of cell factories is the stoichiometric coupling of growth and product synthesis. Based on this approach we recently constructed an Escherichia coli strain producing itaconic acid with excellent yields. Further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34c1b8cb2e221886401ed0fbf069cb9
https://hdl.handle.net/21.11116/0000-0003-7542-F21.11116/0000-0003-756A-3
https://hdl.handle.net/21.11116/0000-0003-7542-F21.11116/0000-0003-756A-3
Autor:
Konstantin M. J. Sparrer, Julian Willibald, Leonhard Möckl, Tobias Halbach, Thomas Carell, Felix Gnerlich, Johannes Harder, Korbinian Brunner, Karl-Klaus Conzelmann, Andreas Beil, Christoph Bräuchle, Fabio Spada
Publikováno v:
Angewandte Chemie. 127:1968-1971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0b06108503011cfc8ab238db3e90df0
https://doi.org/10.1002/ange.201409803
https://doi.org/10.1002/ange.201409803
Publikováno v:
Metabolic engineering. 38
Itaconic acid is a high potential platform chemical which is currently industrially produced by Aspergillus terreus. Heterologous production of itaconic acid with Escherichia coli could help to overcome limitations of A. terreus regarding slow growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc3b5b7e3228940b72cc292fa2603e24
https://pubmed.ncbi.nlm.nih.gov/27269589
https://pubmed.ncbi.nlm.nih.gov/27269589
Autor:
Johannes Harder, Konstantin M. J. Sparrer, Julian Willibald, Thomas Carell, Karl-Klaus Conzelmann
Publikováno v:
Journal of the American Chemical Society. 134:12330-12333
Click chemistry of alkyne-modified RNA with different receptor ligand azides was used to prepare 3'-folate, 3'-cholesterol, and, as a new entity, 3'-anandamide-modified RNA in high yields and excellent purity. The anandamide-modified RNA shows surpri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3ca8b24b91b7b05a82abfa816916b5
https://doi.org/10.1021/ja303251f
https://doi.org/10.1021/ja303251f
Autor:
Julian Willibald, Johannes Harder, Thomas Carell, Fabio Spada, Karl-Klaus Conzelmann, Felix Gnerlich, Andreas Beil, Leonhard Möckl, Korbinian Brunner, Christoph Bräuchle, Tobias Halbach, Konstantin M. J. Sparrer
Publikováno v:
Angewandte Chemie (International ed. in English). 54(6)
We report the development of dendritic siRNA nanostructures that are able to penetrate even difficult to transfect cells such as neurons with the help of a special receptor ligand. The nanoparticles elicit strong siRNA responses, despite the dendriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163cef8d51b6d42115aac6e3a8d7ae79
https://pubmed.ncbi.nlm.nih.gov/25522332
https://pubmed.ncbi.nlm.nih.gov/25522332
Publikováno v:
Biotechnology and Bioengineering
Based on the recently constructed E. coli itaconic acid production strain ita23, we aimed to improve the productivity by applying a two-stage process strategy with decoupled production of biomass and itaconic acid. We constructed a strain ita32 (MG16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d4249bd9ee44da896f383c3956bcd5