Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Johannes H.M. Levels"'
Autor:
Begoña Porteiro, Reinout L.P. Roscam Abbing, Wietse In het Panhuis, Dirk R. de Waart, Suzanne Duijst, Isabelle Bolt, Esther W. Vogels, Johannes H.M. Levels, Laura A. Bosmans, Winnie G. Vos, Ronald P.J. Oude Elferink, Esther Lutgens, Stan F.J. van de Graaf
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 8, Pp 100594- (2024)
Bile salts can strongly influence energy metabolism through systemic signaling, which can be enhanced by inhibiting the hepatic bile salt transporter Na+ taurocholate cotransporting polypeptide (NTCP), thereby delaying hepatic reuptake of bile salts
Externí odkaz:
https://doaj.org/article/3ec125e1e6b34037b16340136513ac67
Autor:
Madelief Wijdeveld, Anouk Schrantee, Anouk Hagemeijer, Aart J. Nederveen, Torsten P.M. Scheithauer, Johannes H.M. Levels, Andrei Prodan, Willem M. de Vos, Max Nieuwdorp, Richard G. Ijzerman
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108478- (2023)
Summary: Animal studies suggest that short-chain fatty acids acetate and butyrate are key players in the gut-brain axis and may affect insulin sensitivity. We investigated the association of intestinal acetate and butyrate availability (measured by b
Externí odkaz:
https://doaj.org/article/09d4dd24ff9c4f06bae958ab960b6d3d
Autor:
Joanne M. Donkers, Reinout L.P. Roscam Abbing, Michel van Weeghel, Johannes H.M. Levels, Anita Boelen, Alfred H. Schinkel, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 451-466 (2020)
Background & Aims: Bile acids are important metabolic signaling molecules. Bile acid receptor activation promotes body weight loss and improves glycemic control. The incretin hormone GLP-1 and thyroid hormone activation of T4 to T3 have been suggeste
Externí odkaz:
https://doaj.org/article/947ce3d0a1cf41cdb360eb818de0b5b9
Autor:
Alexina Orsoni, Samir Saheb, Johannes H.M. Levels, Geesje Dallinga-Thie, Marielle Atassi, Randa Bittar, Paul Robillard, Eric Bruckert, Anatol Kontush, Alain Carrié, M. John Chapman
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2304-2313 (2011)
Subnormal HDL-cholesterol (HDL-C) and apolipoprotein (apo)AI levels are characteristic of familial hypercholesterolemia (FH), reflecting perturbed intravascular metabolism with compositional anomalies in HDL particles, including apoE enrichment. Does
Externí odkaz:
https://doaj.org/article/48a81323fae341548899f14a6d53d6e1
Autor:
Carlos L.J. Vrins, Astrid E. van der Velde, Karin van den Oever, Johannes H.M. Levels, Stephane Huet, Ronald P.J. Oude Elferink, Folkert Kuipers, Albert K. Groen
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 10, Pp 2046-2054 (2009)
Peroxisome proliferator-activated receptor delta (PPARδ) is involved in regulation of energy homeostasis. Activation of PPARδ markedly increases fecal neutral sterol secretion, the last step in reverse cholesterol transport. This phenomenon can nei
Externí odkaz:
https://doaj.org/article/1cebb82e80634134a03c2b7d623df456
Autor:
Radjesh J. Bisoendial, John J.P. Kastelein, Stephan L.M. Peters, Johannes H.M. Levels, Rakesh Birjmohun, Joris I. Rotmans, Daniel Hartman, Joost C.M. Meijers, Marcel Levi, Erik S.G. Stroes
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 4, Pp 952-960 (2007)
C-reactive protein (CRP) has been suggested to exert direct adverse effects on the vasculature in experimental setups, including endothelial dysfunction and proinflammatory changes. Here, we assessed the consequences of 1.25 mg/kg highly purified rec
Externí odkaz:
https://doaj.org/article/ed37823683e3476eb59e1c27d2a03cb2
Autor:
Wim A. van der Steeg, G. Kees Hovingh, Anke H.E.M. Klerkx, Barbara A. Hutten, Inge C. Nootenboom, Johannes H.M. Levels, Arie van Tol, Gees M. Dallinga-Thie, Aeilko H. Zwinderman, John J.P. Kastelein, Jan Albert Kuivenhoven
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 3, Pp 674-682 (2007)
It is unclear whether cholesteryl ester transfer protein (CETP) contributes to high density lipoprotein cholesterol (HDL-C) levels in hyperalphalipoproteinemia (HALP) in Caucasians. Moreover, even less is known about the effects of hereditary CETP de
Externí odkaz:
https://doaj.org/article/eddad90b9ae148ca8cade459539d23af
Autor:
Johannes H.M. Levels, Fredrik Bäckhed, Mireille J. Serlie, Albert K. Groen, Andrei Prodan, Hilde Herrema, Max Nieuwdorp, Frits Holleman, Joost B. L. Hoekstra, Amber Sales, Torsten P. M. Scheithauer, Geesje M. Dallinga-Thie, Jacques J. Bergman, Evgeni Levin, Pieter F. de Groot, Alinda W. M. Schimmel, Guido J. Bakker, Mariëtte T. Ackermans, Muhammad Tanweer Khan, Victor E. A. Gerdes, Maurits de Brauw, Marcus Ståhlman
Publikováno v:
Gut, 502-512. BMJ Publishing Group
STARTPAGE=502;ENDPAGE=512;ISSN=0017-5749;TITLE=Gut
Gut, 69, 502-512. BMJ Publishing Group
Gut
de Groot, P, Scheithauer, T, Bakker, G J, Prodan, A, Levin, E, Khan, M T, Herrema, H, Ackermans, M, Serlie, M J M, de Brauw, M, Levels, J H M, Sales, A, Gerdes, V E, Ståhlman, M, Schimmel, A W M, Dallinga-Thie, G, Bergman, J J, Holleman, F, Hoekstra, J B L, Groen, A, Bäckhed, F & Nieuwdorp, M 2019, ' Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time ', Gut, pp. 502-512 . https://doi.org/10.1136/gutjnl-2019-318320
STARTPAGE=502;ENDPAGE=512;ISSN=0017-5749;TITLE=Gut
Gut, 69, 502-512. BMJ Publishing Group
Gut
de Groot, P, Scheithauer, T, Bakker, G J, Prodan, A, Levin, E, Khan, M T, Herrema, H, Ackermans, M, Serlie, M J M, de Brauw, M, Levels, J H M, Sales, A, Gerdes, V E, Ståhlman, M, Schimmel, A W M, Dallinga-Thie, G, Bergman, J J, Holleman, F, Hoekstra, J B L, Groen, A, Bäckhed, F & Nieuwdorp, M 2019, ' Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time ', Gut, pp. 502-512 . https://doi.org/10.1136/gutjnl-2019-318320
ObjectiveBariatric surgery improves glucose metabolism. Recent data suggest that faecal microbiota transplantation (FMT) using faeces from postbariatric surgery diet-induced obese mice in germ-free mice improves glucose metabolism and intestinal home
Autor:
Stan F.J. van de Graaf, Reinout L.P. Roscam Abbing, Joanne M. Donkers, Michel van Weeghel, Johannes H.M. Levels, Ronald P.J. Oude Elferink, Anita Boelen, Alfred H. Schinkel
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 451-466 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 10(3), 451-466. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 10(3), 451-466. Elsevier Inc.
Background & Aims Bile acids are important metabolic signaling molecules. Bile acid receptor activation promotes body weight loss and improves glycemic control. The incretin hormone GLP-1 and thyroid hormone activation of T4 to T3 have been suggested
Autor:
Johannes H.M. Levels, Geesje M. Dallinga-Thie, Cleo L. Crunelle, Maryse Guerin, Sacha D. Kuil, Erik S.G. Stroes, Alinda W. M. Schimmel, Lars E. Larsen, Jan Albert Kuivenhoven, Lubna Ali, Vassiliki Konstantopoulou, Marjolein A.W. van den Boogert, Adriaan G. Holleboom, Dirk Lefeber
Publikováno v:
Journal of Inherited Metabolic Disease, 43(3), 611-617. SPRINGER
Journal of Inherited Metabolic Disease
Journal of inherited metabolic disease, 43(3), 611-617. Springer Netherlands
Journal of Inherited Metabolic Disease, 43, 3, pp. 611-617
Journal of Inherited Metabolic Disease, Springer Verlag, 2020, 43 (3), pp.611-617. ⟨10.1002/jimd.12200⟩
Journal of Inherited Metabolic Disease, 43, 611-617
Journal of Inherited Metabolic Disease
Journal of inherited metabolic disease, 43(3), 611-617. Springer Netherlands
Journal of Inherited Metabolic Disease, 43, 3, pp. 611-617
Journal of Inherited Metabolic Disease, Springer Verlag, 2020, 43 (3), pp.611-617. ⟨10.1002/jimd.12200⟩
Journal of Inherited Metabolic Disease, 43, 611-617
Contains fulltext : 220538.pdf (Publisher’s version ) (Open Access) The importance of protein glycosylation in regulating lipid metabolism is becoming increasingly apparent. We set out to further investigate this by studying the effects of defectiv