Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Johannes H. Urban"'
Autor:
Johannes H. Urban, Markus A. Moosmeier, Tobias Aumüller, Marcus Thein, Tjibbe Bosma, Rick Rink, Katharina Groth, Moritz Zulley, Katja Siegers, Kathrin Tissot, Gert N. Moll, Josef Prassler
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Lanthipeptides are a class of cyclic post-translationally modified peptides with potential drug-like properties. Here the authors develop a phage display system by expressing lanthipeptide precursors as C-terminal fusions to the phage M13 coat protei
Externí odkaz:
https://doaj.org/article/6804c6078ad541b2a86a6d200c382069
Autor:
Kathrin Tissot, Gert N. Moll, Marcus Thein, Johannes H. Urban, Moosmeier Markus Andreas, Josef Prassler, Rick Rink, Tjibbe Bosma, Moritz Zulley, Katharina Groth, Tobias Aumüller, Katja Siegers
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are an emerging class of natural products with drug-like properties. To fully exploit the potential of RiPPs as peptide drug candidates, tools for their systematic engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562a8d8798c5240f7b99874067485a1c
http://link.springer.com/article/10.1038/s41467-017-01413-7
http://link.springer.com/article/10.1038/s41467-017-01413-7
Publikováno v:
Nucleic acid therapeutics. 26(3)
Although the use of RNAs has enormous therapeutic potential, these RNA-based therapies can trigger unwanted inflammatory responses by the activation of pattern recognition receptors (PRRs) and cause harmful side effects. In contrast, the immune activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89609ab97031438325e6b7cac03fbb7d
https://pubmed.ncbi.nlm.nih.gov/26789413
https://pubmed.ncbi.nlm.nih.gov/26789413
Superfolder GFP reporters validate diverse new mRNA targets of the classic porin regulator, MicF RNA
Autor:
Colin P. Corcoran, Johannes H. Urban, Kai Papenfort, Jörg Vogel, Jay C. D. Hinton, Dimitri Podkaminski
Publikováno v:
Molecular Microbiology. 84:428-445
MicF is a textbook example of a small regulatory RNA (sRNA) that acts on a trans-encoded target mRNA through imperfect base pairing. Discovery of MicF as a post-transcriptional repressor of the major Escherichia coli porin OmpF established the paradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd5137d7bb230723953e28949e94475
https://doi.org/10.1111/j.1365-2958.2012.08031.x
https://doi.org/10.1111/j.1365-2958.2012.08031.x
Publikováno v:
Journal of Molecular Biology. 373:521-528
Many bacterial genes of related function are organized in operons and transcribed as polycistronic mRNAs to ensure the coordinate expression of the individual cistrons. Post-transcriptional modulation of such mRNAs can alter the expression of downstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245e6b6a07e792e4ea8bebebab5b2a57
https://doi.org/10.1016/j.jmb.2007.07.035
https://doi.org/10.1016/j.jmb.2007.07.035
Autor:
Jing Mi, Zhongguang Yang, Johannes H. Urban, Zahid N. Rabbani, Yingmiao Liu, Bryan M. Clary, Bruce A. Sullenger
Publikováno v:
Nature chemical biology
In an effort to target the in vivo context of tumor-specific moieties, a large library of nuclease-resistant RNA oligonucleotides was screened in tumor-bearing mice to identify candidate molecules with the ability to localize to hepatic colon cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138dbf31f979ec951959ad00225c33f9
https://doi.org/10.1038/nchembio.277
https://doi.org/10.1038/nchembio.277
Publikováno v:
Cancer Vaccines: From Research to Clinical Practice ISBN: 1841848301
Cancer Vaccines: From Research to Clinical Practice
Cancer Vaccines: From Research to Clinical Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fcdf9b7626cf14e89c7b00b76cdae42
https://doi.org/10.3109/9781841848303.016
https://doi.org/10.3109/9781841848303.016
Autor:
Johannes H, Urban, Jörg, Vogel
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 540
Small non-coding RNAs (sRNAs) are an emerging class of regulators of bacterial gene expression, which mainly modulate the translation of trans-encoded mRNAs. Typically, these molecules are 50-200 nucleotides in size and do not contain expressed open
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60fcac1d68afa2ae292eafac6345deda
https://pubmed.ncbi.nlm.nih.gov/19381569
https://pubmed.ncbi.nlm.nih.gov/19381569
Autor:
Johannes H. Urban, Jörg Vogel
Publikováno v:
Methods in Molecular Biology ISBN: 9781934115886
Small non-coding RNAs (sRNAs) are an emerging class of regulators of bacterial gene expression, which mainly modulate the translation of trans-encoded mRNAs. Typically, these molecules are 50-200 nucleotides in size and do not contain expressed open
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33925448ca15d707687e8b2059e516a5
https://doi.org/10.1007/978-1-59745-558-9_22
https://doi.org/10.1007/978-1-59745-558-9_22
Autor:
Johannes H. Urban, Jörg Vogel
Publikováno v:
Nucleic Acids Research
Small non-coding RNAs (sRNAs) are an emerging class of regulators of bacterial gene expression. Most of the regulatory Escherichia coli sRNAs known to date modulate translation of trans-encoded target mRNAs. We studied the specificity of sRNA target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5054437cd6dc38c0246f53095719c12d
https://pubmed.ncbi.nlm.nih.gov/17264113
https://pubmed.ncbi.nlm.nih.gov/17264113