Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Johannes H. Harenberg"'
Autor:
Alexander Kremsmair, Henrik R. Wilke, Johannes H. Harenberg, Benjamin R. G. Bissinger, Matthias M. Simon, Nurtalya Alandini, Paul Knochel
Publikováno v:
Angewandte Chemie. 135
Autor:
Alexander Kremsmair, Henrik R. Wilke, Johannes H. Harenberg, Benjamin R. G. Bissinger, Matthias M. Simon, Nurtalya Alandini, Paul Knochel
Publikováno v:
Angewandte Chemie (International ed. in English).
We report a practical in situ quench (ISQ) procedure involving the generation of chiral secondary alkyllithiums from secondary alkyl iodides (including functionalized iodides bearing an ester or a nitrile) in the presence of various electrophiles suc
Autor:
Paul Knochel, Niels Weidmann, Alexander J. Wiegand, Rajasekar Reddy Annapureddy, Carla A. Hoefer, Johannes H. Harenberg
Publikováno v:
Angewandte Chemie. 133:14416-14421
Publikováno v:
Chemical Science
Polyfunctional organometallics of magnesium and zinc are readily prepared from organic halides via a direct metal insertion in the presence of LiCl or a Br/Mg-exchange using iPrMgCl·LiCl (turbo-Grignard) or related reagents. Alternatively, such func
Publikováno v:
Angewandte Chemie. 134
Publikováno v:
Angewandte Chemie (International ed. in English). 61(30)
We report a lateral sodiation of alkyl(hetero)arenes using on-demand generated hexane-soluble (2-ethylhexyl)sodium (1) in the presence of TMEDA. (2-Ethylhexyl)sodium (1) is prepared via a sodium packed-bed reactor and used for metalations at ambient
Publikováno v:
Angewandte Chemie. 133:742-746
Publikováno v:
Angewandte Chemie (International Ed. in English)
The sodiation of substituted acrylonitriles and alkenyl sulfides in a continuous flow set‐up using NaDA (sodium diisopropylamide) in EtNMe2 or NaTMP (sodium 2,2,6,6‐tetramethylpiperidide)⋅TMEDA in n‐hexane provides sodiated acrylonitriles and
Publikováno v:
Synlett. 31:1880-1887
The generation of reactive organometallic reagents in batch is often complicated by the low thermal stability of these important synthetic intermediates and can require low reaction temperatures and special reaction conditions. However, the use of co
Publikováno v:
Synthesis. 53:557-568
A halogen–lithium exchange reaction of (hetero)aromatic halides performed in the presence of various electrophiles such as aldehydes, ketones, Weinreb amides, and imines using BuLi as exchange reagent and a commercially available flow set-up is rep