Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Johannes Gibhardt"'
Publikováno v:
microLife. 4
Cyclic di-AMP is an emerging second messenger that is synthesized by many archaea and bacteria, including the Gram-positive pathogenic bacterium Listeria monocytogenes. Listeria monocytogenes played a crucial role in elucidating the essential functio
Autor:
Rica Bremenkamp, Jonathan Rosenberg, Ralf Ficner, Roland Seifert, Volkhard Kaever, Johannes Gibhardt, Jana L. Heidemann, Fabian M. Commichau
Publikováno v:
Environmental Microbiology. 22:2771-2791
The second messenger cyclic di-AMP (c-di-AMP) is essential for growth of many bacteria because it controls osmolyte homeostasis. c-di-AMP can regulate the synthesis of potassium uptake systems in some bacteria and it also directly inhibits and activa
Autor:
Mengyi Wang, Sabrina Wamp, Johannes Gibhardt, Gudrun Holland, Inge Schwedt, Kai‐Uwe Schmidtke, Katrin Scheibner, Sven Halbedel, Fabian M. Commichau
Publikováno v:
Environmental microbiologyReferences. 24(9)
The human pathogen Listeria monocytogenes synthesizes and degrades c-di-AMP using the diadenylate cyclase CdaA and the phosphodiesterases PdeA and PgpH respectively. c-di-AMP is essential because it prevents the uncontrolled uptake of osmolytes. Here
Autor:
Johannes Gibhardt, Gregor Hoffmann, Asan Turdiev, Vincent T. Lee, Mengyi Wang, Fabian M. Commichau
Publikováno v:
Journal of Biological Chemistry. 294:16020-16033
Many bacteria and some archaea produce the second messenger cyclic diadenosine monophosphate (c-di-AMP). c-di-AMP controls the uptake of osmolytes in Firmicutes, including the human pathogen Listeria monocytogenes, making it essential for growth. c-d
Autor:
Rolf Müller, Jennifer Herrmann, Marcus Miethke, Samuel Hauf, Fabian M. Commichau, Johannes Gibhardt, Stephan Fuchs, Sven Halbedel
Publikováno v:
Molecular microbiology
Bacteria can cope with toxic compounds such as antibiotics by inducing genes for their detoxification. A common detoxification strategy is compound excretion by ATP-binding cassette (ABC) transporters, which are synthesized upon compound contact. We
Autor:
Lisa Maria Schulz, Dennis Wicke, Johannes Gibhardt, Fabian M. Commichau, Sabine Lentes, Anja Poehlein, Rolf Daniel, Patricia Scholz, Till Ischebeck
Publikováno v:
Environmental Microbiology. 21:1287-1305
The soil bacterium Bacillus subtilis can get into contact with growth-inhibiting substances, which may be of anthropogenic origin. Glyphosate is such a substance serving as a nonselective herbicide. Glyphosate specifically inhibits the 5-enolpyruvyl-
Publikováno v:
Environmental microbiologyReferences. 23(6)
Glyphosate is a nonselective herbicide that kills weeds and other plants competing with crops. Glyphosate specifically inhibits the 5-enolpyruvyl-shikimate-3-phosphate (EPSP) synthase, thereby depleting the cell of EPSP serving as a precursor for bio
Publikováno v:
Trends in Microbiology. 26:175-185
Bacteria use second-messenger molecules to adapt to their environment. Several second messengers, among them cyclic di-AMP (c-di-AMP), have been discovered and intensively studied. Interestingly, c-di-AMP is essential for growth of Gram-positive bact
Autor:
Johannes, Gibhardt, Gregor, Hoffmann, Asan, Turdiev, Mengyi, Wang, Vincent T, Lee, Fabian M, Commichau
Publikováno v:
J Biol Chem
Many bacteria and some archaea produce the second messenger cyclic diadenosine monophosphate (c-di-AMP). c-di-AMP controls the uptake of osmolytes in Firmicutes, including the human pathogen Listeria monocytogenes, making it essential for growth. c-d
Autor:
Vincent T. Lee, Jörg Stülke, Johannes Gibhardt, Christian Magni, Elke Hammer, Ingrid María Quintana, Fabian M. Commichau, Asan Turdiev
Publikováno v:
Journal of Bacteriology. 201
Cyclic di-AMP (c-di-AMP) is a second messenger involved in diverse metabolic processes, including osmolyte uptake, cell wall homeostasis, and antibiotic and heat resistance. In Lactococcus lactis, a lactic acid bacterium which is used in the dairy in