Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Johannes G. Wittig"'
Autor:
Maria-Cristina Keightley, Duncan P. Carradice, Judith E. Layton, Luke Pase, Julien Y. Bertrand, Johannes G. Wittig, Aleksandar Dakic, Andrew P. Badrock, Nicholas J. Cole, David Traver, Stephen L. Nutt, Julia McCoey, Ashley M. Buckle, Joan K. Heath, Graham J. Lieschke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Neutrophils are increased in response to injury and infection but how they form from a common granulocyte-macrophage progenitor is unclear. Here, the authors identify a role for the transcriptional repressor ZBTB11 in zebrafish, which is regulated by
Externí odkaz:
https://doaj.org/article/3c95ab3a3ca641e6961f1263d836b9c2
Autor:
Johannes G. Wittig, Andrea Münsterberg
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 2, p 12 (2016)
The heart is the first functioning organ in the developing embryo and a detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the
Externí odkaz:
https://doaj.org/article/014c2a580d404b6ca1fda61352624ed1
Autor:
Miguel Robles García, Johannes G. Wittig, Andrea Münsterberg, Martina Billmeier, Estefanía Lozano-Velasco
Background Studying microRNA networks during heart development is essential to obtain a better understanding of developmental defects and diseases associated with the heart and to identify novel opportunities for therapeutics. Here we highlight the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a0cf6a533186a25a7498f0be67e907
https://ueaeprints.uea.ac.uk/id/eprint/69045/
https://ueaeprints.uea.ac.uk/id/eprint/69045/
Autor:
Andrea Münsterberg, Johannes G. Wittig
Publikováno v:
Cold Spring Harb Perspect Biol
Heart development is a complex process and begins with the long-range migration of cardiac progenitor cells during gastrulation. This culminates in the formation of a simple contractile tube with multiple layers, which undergoes remodeling into a fou
Autor:
Alexander S. Hebert, Catherine E. Minogue, Daniel E. Bauer, John D. Phillips, Tamara A. Dailey, Liangtao Li, Emma E. Coughlin, Jacky Chung, Hector A. Bergonia, Alan B. Cantor, Takahiro Maeda, Joshua J. Coon, Harry A. Dailey, Martin D. Kafina, Harvey F. Lodish, Barry H. Paw, Manami Maeda, Stuart H. Orkin, Alireza Ghamari, Jerry Kaplan, David J. Pagliarini, Johannes G. Wittig
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64864df498d5f9e01442e403f098522e
https://ueaeprints.uea.ac.uk/id/eprint/63655/
https://ueaeprints.uea.ac.uk/id/eprint/63655/
Autor:
David Traver, Andrew P. Badrock, Aleksandar Dakic, Ashley M. Buckle, Maria-Cristina Keightley, Stephen L. Nutt, Judith E. Layton, Julia M. McCoey, Joan K. Heath, Graham J. Lieschke, Luke Pase, Johannes G. Wittig, Nicholas J. Cole, Julien Y. Bertrand, Duncan P. Carradice
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol. 8 (2017) P. 14911
Keightley, M C, Carradice, D P, Layton, J E, Pase, L, Bertrand, J Y, Wittig, J G, Dakic, A, Badrock, A P, Cole, N J, Traver, D, Nutt, S L, McCoey, J, Buckle, A M, Heath, J K & Lieschke, G J 2017, ' The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger ', Nature Communications, vol. 8, 14911 . https://doi.org/10.1038/ncomms14911
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol. 8 (2017) P. 14911
Keightley, M C, Carradice, D P, Layton, J E, Pase, L, Bertrand, J Y, Wittig, J G, Dakic, A, Badrock, A P, Cole, N J, Traver, D, Nutt, S L, McCoey, J, Buckle, A M, Heath, J K & Lieschke, G J 2017, ' The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger ', Nature Communications, vol. 8, 14911 . https://doi.org/10.1038/ncomms14911
In response to infection and injury, the neutrophil population rapidly expands and then quickly re-establishes the basal state when inflammation resolves. The exact pathways governing neutrophil/macrophage lineage outputs from a common granulocyte-ma
Autor:
Alireza Ghamari, Daniel E. Bauer, Jacky Chung, Catherine E. Minogue, Martin D. Kafina, Harvey F. Lodish, Jerry Kaplan, Joshua J. Coon, John D. Phillips, Hector A. Bergonia, David J. Pagliarini, Stuart H. Orkin, Manami Maeda, Barry H. Paw, Tamara A. Dailey, Alexander S. Hebert, Harry A. Dailey, Alan B. Cantor, Johannes G. Wittig, Takahiro Maeda, Liangtao Li, Emma E. Coughlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfce966f76e9febdd15d3c5c2dc22764
https://doi.org/10.7554/elife.24767.018
https://doi.org/10.7554/elife.24767.018
Autor:
Christopher P. Nizzi, Jacky Chung, Daniel E. Bauer, James Palis, Yvette Y. Yien, Caiyong Chen, Paul D. Kingsley, Stuart H. Orkin, Arthur J. Dalton, Iman J. Schultz, Harvey F. Lodish, Alireza Ghamari, Kathryn M. Deck, Richard S. Eisenstein, Alan B. Cantor, Barry H. Paw, Nicholas C. Huston, Johannes G. Wittig
Publikováno v:
PMC
In multicellular organisms, the mechanisms by which diverse cell types acquire distinct amino acids and how cellular function adapts to their availability are fundamental questions in biology. We found that increased neutral essential amino acid (NEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1926f77e0d1ce27b38c2268706f06d4e
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-7029-7415
Publikováno v:
Mechanisms of Development. 145:S155
Autor:
Sumon Datta, Luanne L. Peters, Kathryn M. Deck, Jerry Kaplan, Michael J. Chen, George C. Shaw, Amy J. Lambert, Nicholas C. Huston, Sheila A. Anderson, Matthias W. Hentze, Zong Wei, Nathaniel B. Langer, Babette Gwynn, Liangtao Li, Richard S. Eisenstein, Kenneth E. Sahr, Jacky Chung, Bruno Galy, Wen Chen, Diane M. Ward, Wange Lu, Barry H. Paw, Prasad N. Paradkar, Thorsten M. Schlaeger, Leah F. Boyer, Johannes G. Wittig
Mitochondrial iron is essential for the biosynthesis of heme and iron-sulfur ([Fe-S]) clusters in mammalian cells. In developing erythrocytes, iron is imported into the mitochondria by MFRN1 (mitoferrin-1, SLC25A37). Although loss of MFRN1 in zebrafi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03f726b818204f4ff0573df0704e4df
https://europepmc.org/articles/PMC3953295/
https://europepmc.org/articles/PMC3953295/