Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Johannes G Reiter"'
Autor:
Ivana Bozic, Johannes G Reiter, Benjamin Allen, Tibor Antal, Krishnendu Chatterjee, Preya Shah, Yo Sup Moon, Amin Yaqubie, Nicole Kelly, Dung T Le, Evan J Lipson, Paul B Chapman, Luis A Diaz Jr, Bert Vogelstein, Martin A Nowak
Publikováno v:
eLife, Vol 2 (2013)
In solid tumors, targeted treatments can lead to dramatic regressions, but responses are often short-lived because resistant cancer cells arise. The major strategy proposed for overcoming resistance is combination therapy. We present a mathematical m
Externí odkaz:
https://doaj.org/article/2e4d3630f0974d5aa1b77fee6e5a9d66
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80814 (2013)
Cooperative behavior, where one individual incurs a cost to help another, is a wide spread phenomenon. Here we study direct reciprocity in the context of the alternating Prisoner's Dilemma. We consider all strategies that can be implemented by one an
Externí odkaz:
https://doaj.org/article/846ccc8606474781b2771b3f8711f9c8
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Figures S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20b9f9455c55ab9c9d3787b7aadb2c5
https://doi.org/10.1158/2159-8290.22535195.v1
https://doi.org/10.1158/2159-8290.22535195.v1
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Supplemental Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199151f3e69542070ed2df494bce9bbb
https://doi.org/10.1158/2159-8290.22535192.v1
https://doi.org/10.1158/2159-8290.22535192.v1
Autor:
Alexander V Penson, Jeffrey M. Gerold, Mithat Gonen, Alvin Makohon-Moore, Johannes G. Reiter, Eileen M. O'Reilly, Lance Zhang, Alexander Heyde, Craig M. Bielski, Christine A. Iacobuzio-Donahue, Debyani Chakravarty, Akimasa Hayashi, Jerry P. Melchor, Hitomi Sakamoto, Nicholas D. Socci, Martin A. Nowak, Marc A. Attiyeh, Laura D. Wood, Jungeui Hong, Rajya Kappagantula, Ralph H. Hruban, Barry S. Taylor
Publikováno v:
Cancer Discovery. 10:792-805
Surgery is the only curative option for stage I/II pancreatic cancer; nonetheless, most patients will experience a recurrence after surgery and die of their disease. To identify novel opportunities for management of recurrent pancreatic cancer, we pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832432c2e9cbc201f0a8b5da7f1be972
https://doi.org/10.1158/2159-8290.cd-19-1508
https://doi.org/10.1158/2159-8290.cd-19-1508
Autor:
Preethi Srinivasan, Boris Gutman, Vasily Aushev, Shruti Sharma, Taly Arbel, Hsin-Ta Wu, Meenakshi Malhotra, Raheleh Salari, Bernhard Zimmermann, Ryan Swenerton, Trupti Kawli, Breeana Mitchell, Matthew Rabinowitz, Alexey Aleshin, Johannes G. Reiter
Publikováno v:
Cancer Prevention Research. 16:P040-P040
Introduction: Early cancer detection with liquid biopsies has the potential to reduce mortality rates by improving screening strategies, adoption, and adherence. Towards this, a deeper understanding of the cancer genomic landscape among patients of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63c875e7252b1a5e3af443fc413fcc6e
https://doi.org/10.1158/1940-6215.precprev22-p040
https://doi.org/10.1158/1940-6215.precprev22-p040
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The success of cancer treatment largely depends on the genetic mutations present within metastases, which cause 90% of cancer-related deaths. Genetically diverse metastases are more likely to harbor resistance mutations, contributing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f33f5186bdb9322a71ad89a15acd8e
https://doi.org/10.1073/pnas.1819408116
https://doi.org/10.1073/pnas.1819408116
Autor:
Wandi Zhang, Kanti R. Rai, John G. Gribben, Kristen E. Stevenson, Gad Getz, Catherine J. Wu, Oriol Olive, Alicia Wong, Laura Z. Rassenti, Stacey M. Fernandes, Jennifer R. Brown, Reaha Goyetche, Ivana Bozic, Johannes G. Reiter, Amaro Taylor-Weiner, Carrie Cibulskis, Thomas J. Kipps, Donna Neuberg, Daniel Rosebrock, Ignaty Leshchiner, Chip Stewart, Martin A. Nowak, Michael J. Keating, Dimitri Livitz, Michaela Gruber, Jing Sun, Jeffrey M. Gerold
Publikováno v:
Nature, vol 570, iss 7762
How the genomic features of a patient’s cancer relate to individual disease kinetics remains poorly understood. Here we used the indolent growth dynamics of chronic lymphocytic leukaemia (CLL) to analyse the growth rates and corresponding genomic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c601b84e299f23cd593df221cf7f498
https://doi.org/10.1038/s41586-019-1252-x
https://doi.org/10.1038/s41586-019-1252-x
Autor:
Katherine McNamara, Ruping Sun, S-F Chin, Je Lang, Helen Bardwell, Debu Tripathy, Michael F. Press, Akshara Singareeka Raghavendra, Victoria Forte, Johannes G. Reiter, Carlos Suárez, Zheng Hu, Elena Provenzano, Robert B. West, Christina Curtis, Susanne Tilk, C Caldas, Jennifer L. Caswell-Jin, Zhicheng Ma
Publikováno v:
Cancer Research. 79:P3-06
Background: Understanding to what extent a breast tumor's genetic composition may change over the course of a few months of neoadjuvant therapy has implications for optimal therapeutic approach. However, genomic changes observed across treatment may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec8d258c37f27cf03787fe7d31654d3
https://doi.org/10.1158/1538-7445.sabcs18-p3-06-01
https://doi.org/10.1158/1538-7445.sabcs18-p3-06-01
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Autor:
Jie Ding, Ruping Sun, Helen Bardwell, Suet-Feung Chin, Akshara Singareeka Raghavendra, Michael F. Press, Johannes G. Reiter, Carlos Suárez, Jennifer L. Caswell-Jin, Robert B. West, Zheng Hu, Debasish Tripathy, Carlos Caldas, Christina Curtis, Zhicheng Ma, Katherine McNamara, Elena Provenzano, Julie E. Lang, Susanne Tilk, Victoria Forte
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Genomic changes observed across treatment may result from either clonal evolution or geographically disparate sampling of heterogeneous tumors. Here we use computational modeling based on analysis of fifteen primary breast tumors and find that appare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01501151c6ec2728b8aa574b645b78b4
http://link.springer.com/article/10.1038/s41467-019-08593-4
http://link.springer.com/article/10.1038/s41467-019-08593-4