Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Johannes G Reiter"'
Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy
Autor:
Jennifer L. Caswell-Jin, Katherine McNamara, Johannes G. Reiter, Ruping Sun, Zheng Hu, Zhicheng Ma, Jie Ding, Carlos J. Suarez, Susanne Tilk, Akshara Raghavendra, Victoria Forte, Suet-Feung Chin, Helen Bardwell, Elena Provenzano, Carlos Caldas, Julie Lang, Robert West, Debu Tripathy, Michael F. Press, Christina Curtis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
When examining the evolution of treatment resistance in breast cancer, perceived genomic changes may be due to clonal evolution or heterogeneous tumors. Here, the authors show that apparent clonal change can in fact be due to pre-treatment heterogene
Externí odkaz:
https://doaj.org/article/3b5c30a996d54c2086cfff5a285a1014
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Social interactions among people are often repeated, and yet it is assumed that simultaneous interactions are independent from one another. Here, Reiter and colleagues describe a conceptual framework where an action in one game can influence the deci
Externí odkaz:
https://doaj.org/article/518c3894b3ba486192f2c960aae8227e
Autor:
Johannes G. Reiter, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Ivana Bozic, Krishnendu Chatterjee, Christine A. Iacobuzio-Donahue, Bert Vogelstein, Martin A. Nowak
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Tumours frequently metastasize to multiple anatomical sites and understanding how these different metastases evolve may be important for therapy. Here, the authors develop a method—Treeomics—that can construct phylogenies from multiple metastases
Externí odkaz:
https://doaj.org/article/094af776195f4129b91a819f0e100749
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Figures S1-S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20b9f9455c55ab9c9d3787b7aadb2c5
https://doi.org/10.1158/2159-8290.22535195.v1
https://doi.org/10.1158/2159-8290.22535195.v1
Autor:
Christine A. Iacobuzio-Donahue, Barry S. Taylor, Nicholas D. Socci, Martin A. Nowak, Ralph H. Hruban, Laura D. Wood, Eileen M. O'Reilly, Debyani Chakravarty, Mithat Gönen, Alexander V. Penson, Craig M. Bielski, Alexander Heyde, Johannes G. Reiter, Jerry P. Melchor, Lance Zhang, Rajya Kappagantula, Jungeui Hong, Akimasa Hayashi, Alvin P. Makohon-Moore, Jeffrey M. Gerold, Marc A. Attiyeh, Hitomi Sakamoto
Supplemental Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199151f3e69542070ed2df494bce9bbb
https://doi.org/10.1158/2159-8290.22535192.v1
https://doi.org/10.1158/2159-8290.22535192.v1
Autor:
Preethi Srinivasan, Boris Gutman, Vasily Aushev, Shruti Sharma, Taly Arbel, Hsin-Ta Wu, Meenakshi Malhotra, Raheleh Salari, Bernhard Zimmermann, Ryan Swenerton, Trupti Kawli, Breeana Mitchell, Matthew Rabinowitz, Alexey Aleshin, Johannes G. Reiter
Publikováno v:
Cancer Prevention Research. 16:P040-P040
Introduction: Early cancer detection with liquid biopsies has the potential to reduce mortality rates by improving screening strategies, adoption, and adherence. Towards this, a deeper understanding of the cancer genomic landscape among patients of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63c875e7252b1a5e3af443fc413fcc6e
https://doi.org/10.1158/1940-6215.precprev22-p040
https://doi.org/10.1158/1940-6215.precprev22-p040
Autor:
Jennifer L. Caswell-Jin, Katherine McNamara, Johannes G. Reiter, Ruping Sun, Zheng Hu, Zhicheng Ma, Jie Ding, Carlos J. Suarez, Susanne Tilk, Akshara Raghavendra, Victoria Forte, Suet-Feung Chin, Helen Bardwell, Elena Provenzano, Carlos Caldas, Julie Lang, Robert West, Debu Tripathy, Michael F. Press, Christina Curtis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article omitted from the Author Contributions statement that ‘R.S. and J.G.R contributed equally to this work.’ This has been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/b021138f6e9b4cb1925f14aab5f161ba
Autor:
Alexander V Penson, Jeffrey M. Gerold, Mithat Gonen, Alvin Makohon-Moore, Johannes G. Reiter, Eileen M. O'Reilly, Lance Zhang, Alexander Heyde, Craig M. Bielski, Christine A. Iacobuzio-Donahue, Debyani Chakravarty, Akimasa Hayashi, Jerry P. Melchor, Hitomi Sakamoto, Nicholas D. Socci, Martin A. Nowak, Marc A. Attiyeh, Laura D. Wood, Jungeui Hong, Rajya Kappagantula, Ralph H. Hruban, Barry S. Taylor
Publikováno v:
Cancer Discovery. 10:792-805
Surgery is the only curative option for stage I/II pancreatic cancer; nonetheless, most patients will experience a recurrence after surgery and die of their disease. To identify novel opportunities for management of recurrent pancreatic cancer, we pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832432c2e9cbc201f0a8b5da7f1be972
https://doi.org/10.1158/2159-8290.cd-19-1508
https://doi.org/10.1158/2159-8290.cd-19-1508
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The success of cancer treatment largely depends on the genetic mutations present within metastases, which cause 90% of cancer-related deaths. Genetically diverse metastases are more likely to harbor resistance mutations, contributing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f33f5186bdb9322a71ad89a15acd8e
https://doi.org/10.1073/pnas.1819408116
https://doi.org/10.1073/pnas.1819408116
Autor:
Wandi Zhang, Kanti R. Rai, John G. Gribben, Kristen E. Stevenson, Gad Getz, Catherine J. Wu, Oriol Olive, Alicia Wong, Laura Z. Rassenti, Stacey M. Fernandes, Jennifer R. Brown, Reaha Goyetche, Ivana Bozic, Johannes G. Reiter, Amaro Taylor-Weiner, Carrie Cibulskis, Thomas J. Kipps, Donna Neuberg, Daniel Rosebrock, Ignaty Leshchiner, Chip Stewart, Martin A. Nowak, Michael J. Keating, Dimitri Livitz, Michaela Gruber, Jing Sun, Jeffrey M. Gerold
Publikováno v:
Nature, vol 570, iss 7762
How the genomic features of a patient’s cancer relate to individual disease kinetics remains poorly understood. Here we used the indolent growth dynamics of chronic lymphocytic leukaemia (CLL) to analyse the growth rates and corresponding genomic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c601b84e299f23cd593df221cf7f498
https://doi.org/10.1038/s41586-019-1252-x
https://doi.org/10.1038/s41586-019-1252-x