Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Johannes F. W. Greiner"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The transcription factor NF-κB is commonly known to drive inflammation and cancer progression, but is also a crucial regulator of a broad range of cellular processes within the mammalian nervous system. In the present review, we provide an overview
Externí odkaz:
https://doaj.org/article/f66cdb252ca043509c41eab34af0268d
Autor:
Anna L. Höving, Beatrice A. Windmöller, Cornelius Knabbe, Barbara Kaltschmidt, Christian Kaltschmidt, Johannes F. W. Greiner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Stem cells of the neural crest (NC) vitally participate to embryonic development, but also remain in distinct niches as quiescent neural crest-derived stem cell (NCSC) pools into adulthood. Although NCSC-populations share a high capacity for self-ren
Externí odkaz:
https://doaj.org/article/29dceb30a32c40f1919d6a44eb2ecee5
Autor:
Madlen Merten, Johannes F. W. Greiner, Tarek Niemann, Meike Grosse Venhaus, Daniel Kronenberg, Richard Stange, Dirk Wähnert, Christian Kaltschmidt, Thomas Vordemvenne, Barbara Kaltschmidt
Publikováno v:
Cells, Vol 11, Iss 5, p 823 (2022)
Female sex is increasingly associated with a loss of bone mass during aging and an increased risk of developing nonunion fractures. Hormonal factors and cell-intrinsic mechanisms are suggested to drive these sexual dimorphisms, although underlying mo
Externí odkaz:
https://doaj.org/article/8e869420784646b4a83e146e80d2aafd
Autor:
Barbara Kaltschmidt, Kaya E. Witte, Johannes F. W. Greiner, Florian Weissinger, Christian Kaltschmidt
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 261 (2022)
Among the cell populations existing within a tumor, cancer stem cells are responsible for metastasis formation and chemotherapeutic resistance. In the present review, we focus on the transcription factor NF-κB, which is present in every cell type in
Externí odkaz:
https://doaj.org/article/fe0354e883974da9af6ef19d3c44a471
Publikováno v:
Cells, Vol 10, Iss 8, p 2042 (2021)
NF-κB (nuclear factor kappa B) belongs to a family of transcription factors known to regulate a broad range of processes such as immune cell function, proliferation and cancer, neuroprotection, and long-term memory. Upcoming fields of NF-κB researc
Externí odkaz:
https://doaj.org/article/baf6fd5a3da047fe986d64c17b4de7da
Autor:
Anna L. Höving, Julian Schmitz, Kazuko E. Schmidt, Johannes F. W. Greiner, Cornelius Knabbe, Barbara Kaltschmidt, Alexander Grünberger, Christian Kaltschmidt
Publikováno v:
Biology, Vol 10, Iss 8, p 708 (2021)
Migratory capabilities of adult human stem cells are vital for assuring endogenous tissue regeneration and stem cell-based clinical applications. Although human blood serum has been shown to be beneficial for cell migration and proliferation, little
Externí odkaz:
https://doaj.org/article/549fd27b6f7e4286aa2b348b331de1d1
Autor:
Beatrice A. Windmöller, Morris Beshay, Laureen P. Helweg, Clara Flottmann, Miriam Beermann, Christine Förster, Ludwig Wilkens, Johannes F. W. Greiner, Christian Kaltschmidt, Barbara Kaltschmidt
Publikováno v:
Cells, Vol 10, Iss 5, p 1024 (2021)
There is growing evidence that cancer stem cells (CSCs), a small subpopulation of self-renewal cancer cells, are responsible for tumor growth, treatment resistance, and cancer relapse and are thus of enormous clinical interest. Here, we aimed to isol
Externí odkaz:
https://doaj.org/article/b4ff40d1a93346bbbe527219abbbd41c
Autor:
Anna L. Höving, Katharina Sielemann, Johannes F. W. Greiner, Barbara Kaltschmidt, Cornelius Knabbe, Christian Kaltschmidt
Publikováno v:
Biology, Vol 9, Iss 12, p 435 (2020)
For the identification of a stem cell population, the comparison of transcriptome data enables the simultaneous analysis of tens of thousands of molecular markers and thus enables the precise distinction of even closely related populations. Here, we
Externí odkaz:
https://doaj.org/article/bc6a685c9b0e4888876c4d97a444741a
Autor:
Anna L. Höving, Kazuko E. Schmidt, Madlen Merten, Jassin Hamidi, Ann-Katrin Rott, Isabel Faust, Johannes F. W. Greiner, Jan Gummert, Barbara Kaltschmidt, Christian Kaltschmidt, Cornelius Knabbe
Publikováno v:
Cells, Vol 9, Iss 6, p 1472 (2020)
During aging, senescent cells accumulate in various tissues accompanied by decreased regenerative capacities of quiescent stem cells, resulting in deteriorated organ function and overall degeneration. In this regard, the adult human heart with a gene
Externí odkaz:
https://doaj.org/article/245b264f33af44c19efd1b718d68202f
Autor:
Bernhard P. Kaltschmidt, Inga Ennen, Johannes F. W. Greiner, Robin Dietsch, Anant Patel, Barbara Kaltschmidt, Christian Kaltschmidt, Andreas Hütten
Publikováno v:
Biomedicines, Vol 8, Iss 5, p 105 (2020)
Terpenoids are natural plant-derived products that are applied to treat a broad range of human diseases, such as airway infections and inflammation. However, pharmaceutical applications of terpenoids against bacterial infection remain challenging due
Externí odkaz:
https://doaj.org/article/0930de264efe4e0b91da0d910988be58