Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Johannes Eckstein"'
Alterations of Central Liver Metabolism of Pediatric Patients with Non-Alcoholic Fatty Liver Disease
Autor:
Nikolaus Berndt, Christian A. Hudert, Johannes Eckstein, Christoph Loddenkemper, Stephan Henning, Philip Bufler, David Meierhofer, Ingolf Sack, Susanna Wiegand, Iwona Wallach, Hermann-Georg Holzhütter
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11072 (2022)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children and is associated with overweight and insulin resistance (IR). Almost nothing is known about in vivo alterations of liver metabolism in NAFLD, especially i
Externí odkaz:
https://doaj.org/article/143b69babebf49dbae451653a66c6e0b
Autor:
Nikolaus Berndt, Johannes Eckstein, Niklas Heucke, Robert Gajowski, Martin Stockmann, David Meierhofer, Hermann-Georg Holzhütter
Publikováno v:
Cells, Vol 8, Iss 5, p 512 (2019)
Human hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults and the most common cause of death in people with cirrhosis. While previous metabolic studies of HCC have mainly focused on the glucose metabolism (Warburg
Externí odkaz:
https://doaj.org/article/196e2b306ba540dfb3c9206e27e7504b
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 2, p e1004033 (2015)
The bile fluid contains various lipids that are secreted at the canalicular membrane of hepatocytes. As the secretion mechanism is still a matter of debate and a direct experimental observation of the secretion process is not possible so far, we used
Externí odkaz:
https://doaj.org/article/760461f71190459287ed2b43061c8294
Autor:
Anne-Maj Samuelsson, Theda Ulrike Patricia Bartolomaeus, Harithaa Anandakumar, Irene Thowsen, Elham Nikpey, Jianhua Han, Lajos Marko, Kenneth Finne, Olav Tenstad, Johannes Eckstein, Nikolaus Berndt, Titus Kühne, Sarah Kedziora, Ibrahim Sultan, Trude Skogstrand, Tine V Karlsen, Harri Nurmi, Sofia K Forslund, Entela Bollano, Kari Alitalo, Dominik N Muller, Helge Wiig
Publikováno v:
Cardiovascular Research.
Aims Cardiac energy metabolism is centrally involved in heart failure (HF), although the direction of the metabolic alterations is complex and likely dependent on the particular stage of HF progression. Vascular endothelial growth factor B (VEGF-B) h
Autor:
Anja Hennemuth, Iwona Wallach, Leonid Goubergrits, Tilman Grune, Marie Schafstedde, Nikolaus Berndt, Philipp Mertins, Johannes Eckstein, Titus Kuehne, Milena Kraus, Sarah Nordmeyer, Marieluise Kirchner, Hermann-Georg Holzhütter, Marcus Kelm
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Many heart diseases can result in reduced pumping capacity of the heart muscle. A mismatch between ATP demand and ATP production of cardiomyocytes is one of the possible causes.
Background: Many heart diseases can result in reduced pumping capacity of the heart muscle. A mismatch between ATP demand and ATP production of cardiomyocytes is one of the possible causes.
Indonesia, Southeast Asia's largest economy, ranks globally among the top countries in terms of the envisioned expansion of coal-fired power plants. Despite strongly falling costs for key renewable energies in recent decades, most outstandingly solar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f69fef40a36365a837d8804d6950d3
https://publica.fraunhofer.de/handle/publica/417625
https://publica.fraunhofer.de/handle/publica/417625
Autor:
Oliver Braun, Johannes Eckstein
Publikováno v:
Proceedings ISBN: 9783658370107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5733a95ed618ae40b79d28bbbf80b844
https://doi.org/10.1007/978-3-658-37011-4_2
https://doi.org/10.1007/978-3-658-37011-4_2
Autor:
David Meierhofer, Johannes Eckstein, Hermann-Georg Holzhütter, Fritzi Ott, Nikolaus Berndt, Erik Kolbe, Madlen Matz-Soja, Robert Gajowski
Publikováno v:
Hepatology
Background and aims Zone-dependent differences in expression of metabolic enzymes along the portocentral axis of the acinus are a long-known feature of liver metabolism. A prominent example is the preferential localization of the enzyme, glutamine sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa34fc73f1dd10f308943a111acbea9a
https://refubium.fu-berlin.de/handle/fub188/34017
https://refubium.fu-berlin.de/handle/fub188/34017
Autor:
Clara Bredow, Karin Klingel, Henry Fechner, Anna Paeschke, Lilliana Radoshevich, Fabien Thery, Ziya Kaya, Joachim Spranger, Klaus-Peter Knobeloch, Johannes Eckstein, Antje Beling, Francis Impens, Martin Voß, Eva K. Wirth, Martin Zickler, Nikolaus Berndt, Meike Kespohl, Michael Fähling, Wolfgang Poller
Publikováno v:
SCIENCE ADVANCES
Science Advances
Science Advances
Protein modification with ISG15 acts cooperatively with IFIT proteins and preserves glucose homeostasis.
Protein modification with ISG15 (ISGylation) represents a major type I IFN–induced antimicrobial system. Common mechanisms of action and s
Protein modification with ISG15 (ISGylation) represents a major type I IFN–induced antimicrobial system. Common mechanisms of action and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67ca574b09d70a92f28c41a837f1eb7
https://biblio.ugent.be/publication/8672812
https://biblio.ugent.be/publication/8672812
Autor:
Martin Stockmann, Niklas Heucke, Johannes Eckstein, Nikolaus Berndt, Hermann-Georg Holzhütter, Tilo Wuensch, Robert Gajowski, David Meierhofer
Publikováno v:
The FEBS Journal
Metabolic reprogramming is a characteristic feature of cancer cells, but there is no unique metabolic program for all tumors. Genetic and gene expression studies have revealed heterogeneous inter- and intratumor patterns of metabolic enzymes and memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3423b04aa01686bd6729bca4986893