Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Johannes C. Schoeman"'
Autor:
Min He, Eduard van Wijk, Ruud Berger, Mei Wang, Katrin Strassburg, Johannes C. Schoeman, Rob J. Vreeken, Herman van Wietmarschen, Amy C. Harms, Masaki Kobayashi, Thomas Hankemeier, Jan van der Greef
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Oxylipins play important roles in various biological processes and are considered as mediators of inflammation for a wide range of diseases such as rheumatoid arthritis (RA). The purpose of this research was to study differences in oxylipin levels be
Externí odkaz:
https://doaj.org/article/311e2a59b868497abbc136e4cbc55871
Autor:
Zhengzheng Zhang, Kerina Duri, Kevin L.W. Duisters, Johannes C. Schoeman, Panashe Chandiwana, Peter Lindenburg, Julia Jaeger, Susanne Ziegler, Marcus Altfeld, Isabelle Kohler, Amy Harms, Felicity Z. Gumbo, Thomas Hankemeier, Madeleine J. Bunders
Publikováno v:
AIDS.
Autor:
Herma Renkema, Thomas Hankemeier, Svetlana Pecheritsyna, Julien Beyrath, Jan A.M. Smeitink, Johannes C. Schoeman, X. Jiang, B. Pennings
Publikováno v:
Scientific Reports, 11
Scientific Reports, 11, 880. NATURE RESEARCH
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, 11, 1
Scientific Reports
Scientific Reports, 11, 880. NATURE RESEARCH
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, 11, 1
Scientific Reports
Increased prostaglandin E2 (PGE2) levels were detected in mitochondrial disease patient cells harboring nuclear gene mutations in structural subunits of complex I, using a metabolomics screening approach. The increased levels of this principal inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b38253df834f3ee4c6cba6f252b459
http://hdl.handle.net/2066/231536
http://hdl.handle.net/2066/231536
Autor:
Alireza Mashaghi, Wei Yang, Wendy Stam, Anton Jan van Zonneveld, Thomas Hankemeier, Johannes C. Schoeman, Abidemi Junaid
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
TNFα signaling in the vascular endothelium elicits multiple inflammatory responses that drive vascular destabilization and leakage. Bioactive lipids are main drivers of these processes. In vitro mechanistic studies of bioactive lipids have been larg
Autor:
Henriette J. Scherpbier, Rob J. Vreeken, Liesbeth Van Leeuwen, Ruud Berger, Carools J. Reinecke, Gontse P. Moutloatse, Amy C. Harms, Thomas Hankemeier, Taco W. Kuijpers, Madeleine J. Bunders, Johannes C. Schoeman
Publikováno v:
JOURNAL OF INFECTIOUS DISEASES
JOURNAL OF INFECTIOUS DISEASES, 216(4), 436-446
Journal of Infectious Diseases, 216(4), 436-446. Oxford University Press
The Journal of Infectious Diseases
Journal of infectious diseases, 216(4), 436-446. Oxford University Press
JOURNAL OF INFECTIOUS DISEASES, 216(4), 436-446
Journal of Infectious Diseases, 216(4), 436-446. Oxford University Press
The Journal of Infectious Diseases
Journal of infectious diseases, 216(4), 436-446. Oxford University Press
Summary Here, we show that the mitochondrial and lipid metabolism in uninfected infants born to HIV-1–infected women and with prenatal exposure to combination antiretroviral therapy is dysregulated and is associated with enhanced immune activation.
Autor:
Jörgen Bierau, Annelies Verbon, Jun Hou, Amy C. Harms, Jaap A. Bakker, Thomas Hankemeier, Andre Boonstra, Johannes C. Schoeman, N. Chantal Peltenburg, Fernando Mora, Selwyn H. Lowe
Publikováno v:
Scientific Reports, 8
Scientific Reports, 8, 16947
Scientific Reports, 8:16947. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, 8, 16947
Scientific Reports, 8:16947. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
The HIV-human metabolic relationship is a complex interaction convoluted even more by antiretroviral therapy (cART) and comorbidities. The ability of cART to undo the HIV induced metabolic dysregulation is unclear and under-investigated. Using target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4af32091158aaa51b66af7f4c0c7da
https://hdl.handle.net/1887/70553
https://hdl.handle.net/1887/70553
Autor:
Bart V. J. Cuppen, Floris P J G Lafeber, Rob J. Vreeken, Ruud Berger, Thomas Hankemeier, Herman van Wietmarschen, Junzeng Fu, Amy C. Harms, Jan van der Greef, Johannes C. Schoeman
Publikováno v:
Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, 408(23), 6307–6319. Springer Verlag
Analytical and Bioanalytical Chemistry, 408(23), 6307–6319
Analytical and Bioanalytical Chemistry, 408(23), 6307–6319. Springer Verlag
Analytical and Bioanalytical Chemistry, 408(23), 6307–6319
Oxidised lipids, covering enzymatic and auto-oxidation-synthesised mediators, are important signalling metabolites in inflammation while also providing a readout for oxidative stress, both of which are prominent physiological processes in a plethora
Autor:
Ruud Berger, Rob J. Vreeken, Michel van Weeghel, Thomas Hankemeier, Amy C. Harms, Johannes C. Schoeman
Publikováno v:
Analytical and Bioanalytical Chemistry, 410(10), 2551-2568
Analytical and Bioanalytical Chemistry
Analytical and bioanalytical chemistry, 410(10), 2551-2568. Springer Verlag
Analytical and Bioanalytical Chemistry
Analytical and bioanalytical chemistry, 410(10), 2551-2568. Springer Verlag
Oxidative stress and inflammation are underlying pathogenic mechanisms associated with the progression of several pathological conditions and immunological responses. Elucidating the role of signalling lipid classes, which include, among others, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be728bb5e04a842e786f6c8b90bb230
https://hdl.handle.net/1887/66748
https://hdl.handle.net/1887/66748
Autor:
Thomas Hankemeier, Gontse P. Moutloatse, Mari van Reenen, Carolus J. Reinecke, Zander Lindeque, Madeleine J. Bunders, Johannes C. Schoeman
Publikováno v:
Metabolomics, 13(8). Springer New York
Introduction Untargeted metabolomics of cord blood indicated that antiretroviral therapy to HIV-infected mothers (HIV-ART) did not compromise the exposed neonates with regard to the stress of neonatal hypoglycaemia at birth. However, identified bioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ee35b24c847feddd5d6ddb60889eef
http://hdl.handle.net/1887/3201893
http://hdl.handle.net/1887/3201893