Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Johannes C. Klein"'
Autor:
Conor Owens-Walton, Talia M. Nir, Sarah Al-Bachari, Sonia Ambrogi, Tim J. Anderson, Ítalo Karmann Aventurato, Fernando Cendes, Yao-Liang Chen, Valentina Ciullo, Phil Cook, John C. Dalrymple-Alford, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Rachel Guimarães, Hamied A. Haroon, Rick C. Helmich, Michele T. Hu, Martin E. Johansson, Ho Bin Kim, Johannes C. Klein, Max Laansma, Katherine E. Lawrence, Christine Lochner, Clare Mackay, Corey T. McMillan, Tracy R. Melzer, Leila Nabulsi, Ben Newman, Peter Opriessnig, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Federica Piras, Lukas Pirpamer, Toni L. Pitcher, Kathleen L. Poston, Annerine Roos, Lucas Scárdua Silva, Reinhold Schmidt, Petra Schwingenschuh, Marian Shahid-Besanti, Gianfranco Spalletta, Dan J. Stein, Sophia I. Thomopoulos, Duygu Tosun, Chih-Chien Tsai, Odile A. van den Heuvel, Eva van Heese, Daniela Vecchio, Julio E. Villalón-Reina, Chris Vriend, Jiun-Jie Wang, Yih-Ru Wu, Clarissa Lin Yasuda, Paul M. Thompson, Neda Jahanshad, Ysbrand van der Werf
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous met
Externí odkaz:
https://doaj.org/article/abdb13d4596d46599f5bc49288648bf9
Autor:
Thomas R. Barber, Ludovica Griffanti, Kevin M. Bradley, Daniel R. McGowan, Christine Lo, Clare E. Mackay, Michele T. Hu, Johannes C. Klein
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 1, Pp 26-35 (2020)
Abstract Objectives Rapid eye movement sleep behavior disorder (RBD) patients have a high risk of developing a Parkinsonian disorder, offering an opportunity for neuroprotective intervention. Predicting near‐term conversion, however, remains a chal
Externí odkaz:
https://doaj.org/article/e49d2454783f4722939b38ae3e5f78eb
Autor:
Christine Lo, Siddharth Arora, Fahd Baig, Michael A. Lawton, Claire El Mouden, Thomas R. Barber, Claudio Ruffmann, Johannes C. Klein, Peter Brown, Yoav Ben‐Shlomo, Maarten deVos, Michele T. Hu
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1498-1509 (2019)
Abstract Objective We recently demonstrated that 998 features derived from a simple 7‐minute smartphone test could distinguish between controls, people with Parkinson's and people with idiopathic Rapid Eye Movement sleep behavior disorder, with mea
Externí odkaz:
https://doaj.org/article/46807df211b8446fb949a678609719d6
Autor:
Sarah C. Reitz, Sebastian Luger, Sriramya Lapa, Michael Eibach, Natalie Filmann, Volker Seifert, Lutz Weise, Johannes C. Klein, Jun-Suk Kang, Simon Baudrexel, Johanna Quick-Weller
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Essential Tremor (ET) is a progressive neurological disorder characterized by postural and kinetic tremor most commonly affecting the hands and arms. Medically intractable ET can be treated by deep brain stimulation (DBS) of the ventral i
Externí odkaz:
https://doaj.org/article/61a3436954c6492c87e23202e0bdbf08
Autor:
Lucas Nürnberger, René-Maxime Gracien, Pavel Hok, Stephanie-Michelle Hof, Udo Rüb, Helmuth Steinmetz, Rüdiger Hilker, Johannes C. Klein, Ralf Deichmann, Simon Baudrexel
Publikováno v:
NeuroImage: Clinical, Vol 13, Iss C, Pp 405-414 (2017)
Background: Histological evidence suggests that pathology in Parkinson's disease (PD) goes beyond nigrostriatal degeneration and also affects the cerebral cortex. Quantitative MRI (qMRI) techniques allow the assessment of changes in brain tissue comp
Externí odkaz:
https://doaj.org/article/7323adb0dd564888b98a90e68593bc5f
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 215-227 (2017)
The process of neurodegeneration in Parkinson's disease begins long before the onset of clinical motor symptoms, resulting in substantial cell loss by the time a diagnosis can be made. The period between the onset of neurodegeneration and the develop
Externí odkaz:
https://doaj.org/article/24cc62fb11244e33bf24062925403749
Autor:
Thomas R Barber, Kinan Muhammed, Daniel Drew, Kevin M Bradley, Daniel R McGowan, Johannes C Klein, Sanjay G Manohar, Michele T M Hu, Masud Husain
Publikováno v:
Brain. 146:2502-2511
Idiopathic rapid eye movement sleep behaviour disorder (iRBD) has now been established as an important marker of the prodromal stage of Parkinson’s disease and related synucleinopathies. However, although dopamine transporter single photon emission
Autor:
Yuji Zhao, Eva van Heese, Max A. Laansma, Sarah Al‐Bachari, Tim Anderson, Francesca Assogna, Henk W. Berendse, Joanna Bright, Fernando Cendes, John Dalrymple‐Alford, Ines Debove, Michiel Dirkx, T. Jason Druzgal, Hedley Emsley, JP Fouche, Gaëtan Garraux, Rachel Guimarães, Rick Helmich, Neda Jahanshad, Ho Bin Kim, Johannes C Klein, Christine Lochner, Clare Mackay, Corey T McMillan, Tracy R Melzer, Benjamin T Newman, Conor Owens‐Walton, Laura Parkes, Fabrizio Piras, Toni Pitcher, Kathleen L Poston, Mario Rango, Leticia Franchescheti Ribeiro, Cristiane Rocha, Annerine Roos, Christian Rummel, Lucas Santos, Reinhold Schmidt, Gianfranco Spalletta, Letizia Squarcina, Petra Schwingenschuh, Daniela Vecchio, Chris Vriend, Jiun‐Jie Wang, Daniel Weintraub, Roland Wiest, Clarissa Yasuda, Paul M Thompson, Ysbrand D. van der Werf, Boris A Gutman
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Michael Lawton, Manuela MX Tan, Yoav Ben-Shlomo, Fahd Baig, Thomas Barber, Johannes C Klein, Samuel G Evetts, Stephanie Millin, Naveed Malek, Katherine Grosset, Roger A Barker, Nigel Williams, David J Burn, Thomas Foltynie, Huw R Morris, Nicholas Wood, Donald G Grosset, Michele Tao-Ming Hu
Publikováno v:
Lawton, M A, Tan, M M X, Ben-Shlomo, Y, Baig, F, Barber, T, Klein, J C, Evetts, S G, Millin, S, Malek, N, Grosset, K, Barker, R A, Williams, N, Burn, D J, Foltynie, T, Morris, H R, Wood, N, Grosset, D G & Hu, M T M 2022, ' Genetics of validated Parkinson’s Disease subtypes in the Oxford Discovery and Tracking Parkinson’s cohorts ', Journal of Neurology, Neurosurgery, and Psychiatry, vol. 93, no. 9, pp. 952–959 . https://doi.org/10.1136/jnnp-2021-327376
ObjectivesTo explore the genetics of four Parkinson’s disease (PD) subtypes that have been previously described in two large cohorts of patients with recently diagnosed PD. These subtypes came from a data-driven cluster analysis of phenotypic varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b6dddde338410fc5e014208a6d3f0f
https://hdl.handle.net/1983/e2b3f541-74b1-4b74-a59f-85859656f465
https://hdl.handle.net/1983/e2b3f541-74b1-4b74-a59f-85859656f465
Autor:
Simon Baudrexel, René-Maxime Gracien, Benjamin Stock, Marlies Wagner, Sophie Schöngrundner, Ralf Deichmann, Alexander Seiler, Elke Hattingen, Ulrike Nöth, Helmuth Steinmetz, Johannes C. Klein
Publikováno v:
Aging (Albany NY)
Understanding the microstructural changes related to physiological aging of the cerebral cortex is pivotal to differentiate healthy aging from neurodegenerative processes. The aim of this study was to investigate the age-related global changes of cor