Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Johannes C M, van der Loo"'
Autor:
Lauren M. Timmins, Alexandra M. Burr, Kristina Carroll, Robert Keefe, Matthew Teryek, Louis J. Cantolupo, Johannes C. M. van der Loo, Thomas R.J. Heathman, Adam J Gormley, David Smith, Biju Parekkadan
Publikováno v:
Cell Transplantation, Vol 30 (2021)
When considering the development pathway for a genetically modified cell therapy product, it is critically important that the product is engineered consistent with its intended human use. For scientists looking to develop and commercialize a new tech
Externí odkaz:
https://doaj.org/article/91127e337b6748c391d23c6b3e15f54f
Publikováno v:
Journal of visualized experiments : JoVE. (179)
Adeno-associated viruses (AAV) are promising vectors for gene therapy applications. Here, the AAV2 vector is produced by co-culture of Spodoptera frugiperda (Sf9) cells with Sf9 cells infected with baculovirus (BV)-AAV2-GFP (or therapeutic gene) and
Autor:
David R. Williams, Emmanuel N. Lazaridis, Ryan J. Cooper, Johannes C. M. van der Loo, Helmut Hanenberg, F.-Y. Luo
Publikováno v:
Blood. 92:2556-2570
Mobilized CD34+ cells from human peripheral blood (PB) are increasingly used for hematopoietic stem-cell transplantation. However, the mechanisms involved in the mobilization of human hematopoietic stem and progenitor cells are largely unknown. To st
Autor:
Jane S. A. Voerman, Willem van Ewijk, Pieter J. M. Leenen, Johannes C. M. van der Loo, Marella F. T. R. de Bruijn, Walentina A. T. Slieker
Publikováno v:
European Journal of Immunology, 24(10), 2279-2284. Wiley-VCH
The characterization of early branch points in the differentiation of leukocytes requires identification of precursor cells in the bone marrow. Recently, we produced two monoclonal antibodies, ER‐MP12 and ER‐MP20, which in two‐color flow‐cyto
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 506
Successful retroviral gene transfer into hematopoietic cells has been demonstrated in a number of small and large animal models and clinical trials. However, severe adverse events related to insertional muta-genesis in a recent clinical trial for X-l
Autor:
David R. Williams, Marti F.A. Bierhuizen, Karen E. Pollok, Gerard Wagemaker, Johannes C. M. van der Loo, Emily C. MacNeill, Helmut Hanenberg
Publikováno v:
Journal of Virology, 73(5), 3960-3967. American Society for Microbiology
In many mammalian cells, efficient introduction of genetic material can be accomplished with recombinant retroviral vectors. Retrovirus vectors have also been used as vehicles for gene therapy studies, since many therapeutic applications require inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeadb74de90633f875b7c9f0186bdc51
https://pure.eur.nl/en/publications/80bb8cee-33d6-4f9f-b516-f8dfff144d4a
https://pure.eur.nl/en/publications/80bb8cee-33d6-4f9f-b516-f8dfff144d4a