Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Johannes C M, Schlachetzki"'
Autor:
Bryant Avalos, Jacqueline R. Kulbe, Mary K. Ford, Anna Elizabeth Laird, Kyle Walter, Michael Mante, Jazmin B. Florio, Ali Boustani, Antoine Chaillon, Johannes C. M. Schlachetzki, Erin E. Sundermann, David J. Volsky, Robert A. Rissman, Ronald J. Ellis, Scott L. Letendre, Jennifer Iudicello, Jerel Adam Fields
Publikováno v:
Viruses, Vol 16, Iss 10, p 1509 (2024)
Triggering receptor expressed on myeloid cells 2 (TREM2) is involved in neuroinflammation and HIV-associated neurocognitive impairment (NCI). People with HIV (PWH) using cannabis exhibit lower inflammation and neurological disorders. We hypothesized
Externí odkaz:
https://doaj.org/article/4d637d679e76456dbcdd30adf98db292
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1711-1714 (2021)
The contribution of chronic peripheral inflammation to the pathogenesis of neurodegenerative diseases is an outstanding question. Sustained activation of the peripheral innate and adaptive immune systems occurs in the context of a broad array of diso
Externí odkaz:
https://doaj.org/article/d3704ebd80194323b65cafca80c4d6ea
Autor:
Martin Regensburger, Johannes C. M. Schlachetzki, Jörg Klekamp, Arnd Doerfler, Jürgen Winkler
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background Anterior spinal cord herniation (aSCH) is a rare cause of myelopathy which may present as pure motor syndrome and mimic other degenerative diseases of the spinal cord. In slowly progressive cases, diagnosis may be impeded by equiv
Externí odkaz:
https://doaj.org/article/83333f8709e142ae855e9c82c3ce6f6a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by erosive polyarthritis. Beyond joint pathology, RA is associated with neuropsychiatric comorbidity including depression, anxiety, and an increased risk to develop neurodegene
Externí odkaz:
https://doaj.org/article/2867d34d06f849ce93c79014140a4a83
Autor:
Heiko Gaßner, Franz Marxreiter, Simon Steib, Zacharias Kohl, Johannes C. M. Schlachetzki, Werner Adler, Bjoern M. Eskofier, Klaus Pfeifer, Jürgen Winkler, Jochen Klucken
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
IntroductionCognitive and gait deficits are common symptoms in Parkinson’s disease (PD). Motor-cognitive dual tasks (DTs) are used to explore the interplay between gait and cognition. However, it is unclear if DT gait performance is indicative for
Externí odkaz:
https://doaj.org/article/0c8e8e4112d14b9ca8fef47dd88e544d
Autor:
Dominik Frentzel, Grigorij Judanin, Olga Borozdina, Jochen Klucken, Jürgen Winkler, Johannes C. M. Schlachetzki
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
One striking observation in Parkinson’s disease (PD) is the remarkable gender difference in incidence and prevalence of the disease. Data on gender differences with regard to disease onset, motor and non-motor symptoms, and dopaminergic medication
Externí odkaz:
https://doaj.org/article/5647a106bf9f48f9bbebe25801976fea
Autor:
Johannes C M Schlachetzki, Jens Barth, Franz Marxreiter, Julia Gossler, Zacharias Kohl, Samuel Reinfelder, Heiko Gassner, Kamiar Aminian, Bjoern M Eskofier, Jürgen Winkler, Jochen Klucken
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0183989 (2017)
Distinct gait characteristics like short steps and shuffling gait are prototypical signs commonly observed in Parkinson's disease. Routinely assessed by observation through clinicians, gait is rated as part of categorical clinical scores. There is an
Externí odkaz:
https://doaj.org/article/83d1b789453f4ea88897e357f0733732
Autor:
Zacharias Kohl, Johannes C. M. Schlachetzki, Judith Feldewerth, Philipp Hornauer, Martina Münch, Anthony Adame, Markus J. Riemenschneider, Jürgen Winkler, Eliezer Masliah
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
The olfactory bulb (OB) shows early neuropathological hallmarks in numerous neurodegenerative diseases, for example, in Alzheimer’s disease (AD) and Parkinson’s disease (PD). The glomerular and granular cell layer of the OB is characterized by pr
Externí odkaz:
https://doaj.org/article/3b97e42c520a4a27a43cef33023dd092
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 16, Iss 9, Pp 1711-1714 (2021)
Neural Regeneration Research, Vol 16, Iss 9, Pp 1711-1714 (2021)
The contribution of chronic peripheral inflammation to the pathogenesis of neurodegenerative diseases is an outstanding question. Sustained activation of the peripheral innate and adaptive immune systems occurs in the context of a broad array of diso
Autor:
Kristina Battis, Jazmin B. Florio, Michael Mante, Addison Lana, Isabel Naumann, Carina Gauer, Vera Lambrecht, Simon Julian Müller, Isidoro Cobo, Bethany Fixsen, Ha Yeon Kim, Eliezer Masliah, Christopher K. Glass, Johannes C. M. Schlachetzki, Robert A. Rissman, Jürgen Winkler, Alana Hoffmann
Publikováno v:
J Neurosci
As the CNS-resident macrophages and member of the myeloid lineage, microglia fulfill manifold functions important for brain development and homeostasis. In the context of neurodegenerative diseases, they have been implicated in degenerative and regen