Large and fast human pyramidal neurons associate with intelligence

Autor: Natalia A Goriounova, Djai B Heyer, René Wilbers, Matthijs B Verhoog, Michele Giugliano, Christophe Verbist, Joshua Obermayer, Amber Kerkhofs, Harriët Smeding, Maaike Verberne, Sander Idema, Johannes C Baayen, Anton W Pieneman, Christiaan PJ de Kock, Martin Klein, Huibert D Mansvelder

Publikováno v: eLife, Vol 7 (2018)

It is generally assumed that human intelligence relies on efficient processing by neurons in our brain. Although grey matter thickness and activity of temporal and frontal cortical areas correlate with IQ scores, no direct evidence exists that links

Externí odkaz: https://doaj.org/article/0d4584a6c49c4f01a3d0cd0d00d54850

High bandwidth synaptic communication and frequency tracking in human neocortex.

Autor: Guilherme Testa-Silva, Matthijs B Verhoog, Daniele Linaro, Christiaan P J de Kock, Johannes C Baayen, Rhiannon M Meredith, Chris I De Zeeuw, Michele Giugliano, Huibert D Mansvelder

Publikováno v: PLoS Biology, Vol 12, Iss 11, p e1002007 (2014)

Neuronal firing, synaptic transmission, and its plasticity form the building blocks for processing and storage of information in the brain. It is unknown whether adult human synapses are more efficient in transferring information between neurons than

Externí odkaz: https://doaj.org/article/9d69cd699b934365ad539fdbc5d4baf5

The lesioned brain: still a small world?

Autor: Linda Douw, Edwin Van Dellen, Johannes C Baayen, Martin Klein, Dimitri N Velis, Willem C J Alpherts, Jan J Heimans, Jaap C Reijneveld, Cornelis Jan Stam

Publikováno v: Frontiers in Human Neuroscience, Vol 4 (2010)

The intra-arterial amobarbital procedure (IAP or Wada test) is used to determine language lateralization and contralateral memory functioning in patients eligible for neurosurgery because of pharmaco-resistant epilepsy. During unilateral sedation, fu

Externí odkaz: https://doaj.org/article/bb536f73c36b49ebb4453bd68197730d

Long-term effects of temporal lobe epilepsy on local neural networks: a graph theoretical analysis of corticography recordings.

Autor: Edwin van Dellen, Linda Douw, Johannes C Baayen, Jan J Heimans, Sophie C Ponten, W Peter Vandertop, Demetrios N Velis, Cornelis J Stam, Jaap C Reijneveld

Publikováno v: PLoS ONE, Vol 4, Iss 11, p e8081 (2009)

PURPOSE: Pharmaco-resistant temporal lobe epilepsy (TLE) is often treated with surgical intervention at some point. As epilepsy surgery is considered a last resort by most physicians, a long history of epileptic seizures prior to surgery is not uncom

Externí odkaz: https://doaj.org/article/b1af47fa3f4c4fa7b3d70b79b3d22150

Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex

Autor: Sarah Hunt, Yoni Leibner, Eline J Mertens, Natalí Barros-Zulaica, Lida Kanari, Tim S Heistek, Mahesh M Karnani, Romy Aardse, René Wilbers, Djai B Heyer, Natalia A Goriounova, Matthijs B Verhoog, Guilherme Testa-Silva, Joshua Obermayer, Tamara Versluis, Ruth Benavides-Piccione, Philip de Witt-Hamer, Sander Idema, David P Noske, Johannes C Baayen, Ed S Lein, Javier DeFelipe, Henry Markram, Huibert D Mansvelder, Felix Schürmann, Idan Segev, Christiaan P J de Kock

Publikováno v: Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University Press
Hunt, S, Leibner, Y, Mertens, E J, Barros-Zulaica, N, Kanari, L, Heistek, T S, Karnani, M M, Aardse, R, Wilbers, R, Heyer, D B, Goriounova, N A, Verhoog, M B, Testa-Silva, G, Obermayer, J, Versluis, T, Benavides-Piccione, R, de Witt-Hamer, P, Idema, S, Noske, D P, Baayen, J C, Lein, E S, DeFelipe, J, Markram, H, Mansvelder, H D, Schürmann, F, Segev, I & de Kock, C P J 2023, ' Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex ', Cerebral cortex (New York, N.Y. : 1991), vol. 33, no. 6, pp. 2857-2878 . https://doi.org/10.1093/cercor/bhac246, https://doi.org/10.1093/cercor/bhac246
Cerebral cortex (New York, N.Y. : 1991), 33(6), 2857-2878. Oxford University press

Synaptic transmission constitutes the primary mode of communication between neurons. It is extensively studied in rodent but not human neocortex. We characterized synaptic transmission between pyramidal neurons in layers 2 and 3 using neurosurgically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91045113000d5b810c2551415662a60a
https://doi.org/10.1093/cercor/bhac246