Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Johannes Brockhaus"'
Autor:
Johannes Brockhaus, Iris Kahl, Mohiuddin Ahmad, Daniele Repetto, Carsten Reissner, Markus Missler
Publikováno v:
Cells, Vol 13, Iss 11, p 981 (2024)
Presynaptic Ca2+ influx through voltage-gated Ca2+ channels (VGCCs) is a key signal for synaptic vesicle release. Synaptic neurexins can partially determine the strength of transmission by regulating VGCCs. However, it is unknown whether neurexins mo
Externí odkaz:
https://doaj.org/article/aa43ca8fab874f8fa14b7d6695f9303a
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2022)
Communication between neurons through synapses includes the release of neurotransmitter-containing synaptic vesicles (SVs) and of neuromodulator-containing dense-core vesicles (DCVs). Neurexins (Nrxns), a polymorphic family of cell surface molecules
Externí odkaz:
https://doaj.org/article/398e6a7f7b3044caa90c93e7e9415693
Autor:
Oliver Klatt, Daniele Repetto, Johannes Brockhaus, Carsten Reissner, Abderazzaq El khallouqi, Astrid Rohlmann, Martin Heine, Markus Missler
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109266- (2021)
Summary: Neurexins are key organizer molecules that regulate synaptic function and are implicated in autism and schizophrenia. β-neurexins interact with numerous cell adhesion and receptor molecules, but their neuronal localization remains elusive.
Externí odkaz:
https://doaj.org/article/f8b87c2af88745ffbb2f62451215d42d
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Presynaptic Ca2+ influx through voltage-gated calcium channels (VGCCs) is a key step in synaptic transmission that links action potential (AP)-derived depolarization to vesicle release. However, investigation of presynaptic Ca2+ influx by patch clamp
Externí odkaz:
https://doaj.org/article/10ffc542b5894a42ac7185dc1617dd5d
Autor:
Daniele Repetto, Johannes Brockhaus, Hong J. Rhee, Chungku Lee, Manfred W. Kilimann, Jeongseop Rhee, Lisa M. Northoff, Wenjia Guo, Carsten Reissner, Markus Missler
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Spines are small protrusions from dendrites where most excitatory synapses reside. Changes in number, shape, and size of dendritic spines often reflect changes of neural activity in entire circuits or at individual synapses, making spines key structu
Externí odkaz:
https://doaj.org/article/182c94f3ab21457f8da6f096288d7a4c
Autor:
Stefanie M Geisler, Marta Campiglio, Johannes Brockhaus, Ryuichi Shigemoto, Ruslan I. Stanika, Markus Missler, Bettina Schlick, Gerald J. Obermair, Cornelia Ablinger, Clemens L Schöpf, Walter A. Kaufmann, Benedikt Nimmervoll
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Voltage-gated calcium channels are important regulators of neuronal functions, as for example synaptic transmission. Their auxiliary α2δ subunits are modulating the calcium currents. Beyond that they have emerged as modulators of synap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988b6ad0ab4dd0ed23f671c5e09833bd
https://doi.org/10.1073/pnas.1920827118
https://doi.org/10.1073/pnas.1920827118
Autor:
Keith S. Elmslie, Carsten Reissner, Oliver Klatt, Johannes Brockhaus, Daniele Repetto, Martin Heine, Miriam Schreitmüller, Markus Missler
Publikováno v:
The Journal of Neuroscience. 38:8277-8294
Action potential-evoked neurotransmitter release is impaired in knock-out neurons lacking synaptic cell-adhesion molecules α-neurexins (αNrxns), the extracellularly longer variants of the three vertebrateNrxngenes. Ca2+influx through presynaptic hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecdee359735ee6b0103ef8717f26c63d
https://doi.org/10.1523/jneurosci.0511-18.2018
https://doi.org/10.1523/jneurosci.0511-18.2018
Autor:
Daniele Repetto, Martin Heine, Oliver Klatt, Carsten Reissner, Johannes Brockhaus, Astrid Rohlmann, Markus Missler, Abderazzaq El khallouqi
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109266-(2021)
Summary: Neurexins are key organizer molecules that regulate synaptic function and are implicated in autism and schizophrenia. β-neurexins interact with numerous cell adhesion and receptor molecules, but their neuronal localization remains elusive.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0ac948aaaf506ab9dcfb712fea5eaa
https://doi.org/10.1016/j.celrep.2021.109266
https://doi.org/10.1016/j.celrep.2021.109266
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Presynaptic Ca2+ influx through voltage-gated calcium channels (VGCCs) is a key step in synaptic transmission that links action potential (AP)-derived depolarization to vesicle release. However, investigation of presynaptic Ca2+ influx by patch clamp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddeb93f5a3fc73696b584c1081f1d4a
https://www.frontiersin.org/article/10.3389/fnsyn.2019.00012/full
https://www.frontiersin.org/article/10.3389/fnsyn.2019.00012/full
Autor:
Chungku Lee, Johannes Brockhaus, Wenjia Guo, Markus Missler, Daniele Repetto, Hong Jun Rhee, Jeong-Seop Rhee, Manfred W. Kilimann, Lisa M. Northoff, Carsten Reissner
Publikováno v:
Frontiers in Synaptic Neuroscience
Frontiers in synaptic neuroscience
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Frontiers in synaptic neuroscience
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Spines are small protrusions from dendrites where most excitatory synapses reside. Changes in number, shape, and size of dendritic spines often reflect changes of neural activity in entire circuits or at individual synapses, making spines key structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3553475eb090cbee39c2316ff63c8d82