Human neural network activity reacts to gravity changes in vitro

Autor: Johannes Striebel, Laura Kalinski, Maximilian Sturm, Nils Drouvé, Stefan Peters, Yannick Lichterfeld, Rouhollah Habibey, Jens Hauslage, Sherif El Sheikh, Volker Busskamp, Christian Liemersdorf

Publikováno v: Frontiers in Neuroscience, Vol 17 (2023)

During spaceflight, humans experience a variety of physiological changes due to deviations from familiar earth conditions. Specifically, the lack of gravity is responsible for many effects observed in returning astronauts. These impairments can inclu

Externí odkaz: https://doaj.org/article/cee23121bd2045c8b01d736b0b9bac34

Neuronal Cell-type Engineering by Transcriptional Activation

Autor: Songlei Liu, Johannes Striebel, Giovanni Pasquini, Alex H. M. Ng, Parastoo Khoshakhlagh, George M. Church, Volker Busskamp

Publikováno v: Frontiers in Genome Editing, Vol 3 (2021)

Gene activation with the CRISPR-Cas system has great implications in studying gene function, controlling cellular behavior, and modulating disease progression. In this review, we survey recent studies on targeted gene activation and multiplexed scree

Externí odkaz: https://doaj.org/article/75507b52e26a4dcd9d24a861e8555c2a

Microengineered 2D and 3D modular neuronal networks represent structure-function relationship

Autor: Rouhollah Habibey, Johannes Striebel, Roshanak Latiftikhereshki, Felix Schmieder, Shahrzad Latifi

Brain function is substantially linked to the highly organized structure of neuronal networks. Emerging three-dimensional (3D) neuronal cell culture technologies attempt to mimic the complexity of brain circuits asin vitromicrophysiological systems.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac0f0998d2708e99e52a23d53dc2e1c1
https://doi.org/10.1101/2023.04.07.535751

Optogenetic Control of Human Stem Cell-Derived Neurons

Autor: Rouhollah, Habibey, Johannes, Striebel, Kritika, Sharma, Volker, Busskamp

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2501

Spontaneous and optogenetically evoked activities of human induced pluripotent stem cell (hiPSC)-derived neurons can be assessed by patch clamp and multi-electrode array (MEA) electrophysiology. Optogenetic activation of these human neurons facilitat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9fa36df384641741915a5f0ff2f79c1
https://pubmed.ncbi.nlm.nih.gov/35857237

Controlled Surface Adhesion of Macrophages via Patterned Antifouling Polymer Brushes

Autor: Bingquan Yang, Carsten Weishaupt, Ravi Kumar, Cesar Rodriguez-Emmenegger, Johannes Striebel, Michael Hirtz, Hui-Yu Liu, Mariia Vorobii, Harald Fuchs, Kristina Riehemann

Publikováno v: Advanced NanoBiomed Research, Vol 1, Iss 1, Pp n/a-n/a (2021)
Advanced nanoBiomed research 1(1), 2000029 (2021). doi:10.1002/anbr.202000029
Advanced NanoBiomed Research, 1 (1), Art.Nr. 2000029

Advanced nanoBiomed research 1(1), 2000029 (2021). doi:10.1002/anbr.202000029
Published by Wiley-VCH, Weinheim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4d47e1234d01066d8ea115498acaca
https://doaj.org/article/050819c02e7141408416ab711e5a3ff7