Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Johannes, Herkel"'
Autor:
Daria Krzikalla, Alena Laschtowitz, Lisa Leypoldt, Cornelia Gottwick, Pia Averhoff, Sören Weidemann, Ansgar W. Lohse, Samuel Huber, Christoph Schramm, Dorothee Schwinge, Johannes Herkel, Antonella Carambia
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 79-91 (2024)
Background & Aims: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also can be detrimental by preventing immune sur
Externí odkaz:
https://doaj.org/article/5bdb57d96fae45dab3880fcdea472873
Autor:
Max Preti, Lena Schlott, David Lübbering, Daria Krzikalla, Anna-Lena Müller, Fenja A. Schuran, Tobias Poch, Miriam Schakat, Sören Weidemann, Ansgar W. Lohse, Christina Weiler-Normann, Marcial Sebode, Dorothee Schwinge, Christoph Schramm, Antonella Carambia, Johannes Herkel
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
The liver is an immune-privileged organ that can deactivate autoreactive T cells. Yet in autoimmune hepatitis (AIH), autoreactive T cells can defy hepatic control and attack the liver. To elucidate how tolerance to self-antigens is lost during AIH pa
Externí odkaz:
https://doaj.org/article/562c142691284b8baadaf1974c991cea
Autor:
Marcial Sebode, Jennifer Wigger, Pamela Filpe, Lutz Fischer, Sören Weidemann, Till Krech, Christina Weiler-Normann, Moritz Peiseler, Johannes Hartl, Eva Tolosa, Johannes Herkel, Christoph Schramm, Ansgar W. Lohse, Philomena Arrenberg
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Natural Killer T (NKT) cells are CD1d-restricted innate-like T cells that can rapidly release stored cytokines upon recognition of lipid antigens. In mice, type I NKT cells seem to promote liver inflammation, whereas type II NKT cells see
Externí odkaz:
https://doaj.org/article/54c5a1a0385d42709a8bec56900a540d
Autor:
David Lübbering, Max Preti, Lena Schlott, Christoph Schultheiß, Sören Weidemann, Ansgar W. Lohse, Mascha Binder, Antonella Carambia, Johannes Herkel
Publikováno v:
Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3816514a8def85fffd6407bbc6f8190b
https://doi.org/10.1111/imm.13665
https://doi.org/10.1111/imm.13665
Publikováno v:
Seminars in Immunopathology. 44:475-484
Autoimmune diseases develop when the adaptive immune system attacks the body’s own antigens leading to tissue damage. At least 80 different conditions are believed to have an autoimmune aetiology, including rheumatoid arthritis, type I diabetes, mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04aa6dae12e137a5af1d0ece88a3f6cc
https://doi.org/10.1007/s00281-022-00942-8
https://doi.org/10.1007/s00281-022-00942-8
Autor:
David Lübbering, Max Preti, Lena Schlott, Christoph Schultheiß, Sören Weidemann, AnsgarW. Lohse, Mascha Binder, Antonella Carambia, Johannes Herkel
Publikováno v:
39. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c81e8da1a4d6823fe7425914b466c852
https://doi.org/10.1055/s-0042-1760071
https://doi.org/10.1055/s-0042-1760071
Autor:
Tobias Poch, Johannes Herkel, Luisa Marie Müller, Romina Fiorotto, Antonella Carambia, Till Krech, Lutz Fischer, Dorothee Schwinge, Mario Strazzabosco, S Stein, Lara Henze, Jun Li, M Reich, Nicola Gagliani, M Preti, Christoph Schramm, Verena Keitel, Jonas Wagner, Fenja Amrei Schuran
Publikováno v:
J Hepatol
Background & Aims IL-17A-producing T cells are present in autoimmune cholestatic liver diseases; however, little is known about the contribution of IL-17 to periductal immune responses. Herein, we investigated the role of IL-17 produced by antigen-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72ec9bbf95fed1e7626bf78224b6fb5
https://doi.org/10.1016/j.jhep.2020.10.035
https://doi.org/10.1016/j.jhep.2020.10.035
Autor:
Fenja Amrei Schuran, Ansgar W. Lohse, Carlotta Corban, Disha Mungalpara, Muharrem Şeleci, Joerg Heeren, Cornelia Gottwick, Johannes Herkel, Markus Heine, Antonella Carambia, Dorothee Schwinge, S Stein, Christoph Schramm, Reinaldo Digigow
Publikováno v:
Immunology
Summary Autoimmune diseases are caused by adaptive immune responses to self‐antigens. The development of antigen‐specific therapies that suppress disease‐related, but not unrelated immune responses in general, is an important goal of biomedical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4b891a6a3d5c194dba72636404fa0c
https://doi.org/10.1111/imm.13298
https://doi.org/10.1111/imm.13298
Autor:
Cornelia Gottwick, Daria Krzikalla, LígiaMargaridaMarques Mesquita, Federica Mancini, Marco Fanzutti, Reinaldo Digigow, AnsgarW. Lohse, Antonella Carambia, Johannes Herkel
Publikováno v:
Zeitschrift für Gastroenterologie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01854dbb0f90567662306540a669aa01
https://doi.org/10.1055/s-0041-1740793
https://doi.org/10.1055/s-0041-1740793
Autor:
May Brundert, Joerg Heeren, Martin Merkel, Antonella Carambia, Johannes Herkel, Peter Groitl, Thomas Dobner, Rajasekhar Ramakrishnan, Kathryn J. Moore, Franz Rinninger
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 4, Pp 745-758 (2011)
The mechanisms of HDL-mediated cholesterol transport from peripheral tissues to the liver are incompletely defined. Here the function of scavenger receptor cluster of differentiation 36 (CD36) for HDL uptake by the liver was investigated. CD36 knocko
Externí odkaz:
https://doaj.org/article/c313385d40ab41eebf6bec15f5919260