Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Johannes, Ermert"'
Autor:
Roberta Cologni, Marcus Holschbach, Daniela Schneider, Dirk Bier, Annette Schulze, Carina Stegmayr, Heike Endepols, Johannes Ermert, Felix Neumaier, Bernd Neumaier
Publikováno v:
Molecules, Vol 29, Iss 16, p 3939 (2024)
Mutations of isocitrate dehydrogenase 1 (IDH1) are key biomarkers for glioma classification, but current methods for detection of mutated IDH1 (mIDH1) require invasive tissue sampling and cannot be used for longitudinal studies. Positron emission tom
Externí odkaz:
https://doaj.org/article/2d3f01074a8f4d80b35dfdde0eee8892
Autor:
Cláudia Régio Brambilla, Tanja Veselinović, Ravichandran Rajkumar, Jörg Mauler, Andreas Matusch, Andrej Ruch, Linda Orth, Shukti Ramkiran, Hasan Sbaihat, Nicolas Kaulen, Nibal Yahya Khudeish, Christine Wyss, Karsten Heekeren, Wolfram Kawohl, Elena Rota Kops, Lutz Tellmann, Jürgen Scheins, Frank Boers, Bernd Neumaier, Johannes Ermert, Markus Lang, Stefan Stüsgen, Hans Herzog, Karl-Josef Langen, N. Jon Shah, Christoph W. Lerche, Irene Neuner
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Currently, the metabotropic glutamate receptor 5 (mGluR5) is the subject of several lines of research in the context of neurology and is of high interest as a target for positron-emission tomography (PET). Here, we assessed the feasibility o
Externí odkaz:
https://doaj.org/article/618085a39f9b4b7aad4f13b71a175579
Autor:
Ravichandran Rajkumar, Cláudia Régio Brambilla, Tanja Veselinović, Joshua Bierbrier, Christine Wyss, Shukti Ramkiran, Linda Orth, Markus Lang, Elena Rota Kops, Jörg Mauler, Jürgen Scheins, Bernd Neumaier, Johannes Ermert, Hans Herzog, Karl-Josef Langen, Ferdinand Christoph Binkofski, Christoph Lerche, N. Jon Shah, Irene Neuner
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The symbiosis of neuronal activities and glucose energy metabolism is reflected in the generation of functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) signals. However, their association with the balance between n
Externí odkaz:
https://doaj.org/article/10f2bbeb282f4aa8910e5f423daf0d2b
Autor:
Dennis Oliveira, Carina Stegmayr, Alexander Heinzel, Johannes Ermert, Bernd Neumaier, N. Jon Shah, Felix M. Mottaghy, Karl-Josef Langen, Antje Willuweit
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Background Recent studies reported on high uptake of the PSMA ligands [68Ga]HBED-CC (68Ga-PSMA) and 18F-DCFPyL in cerebral gliomas. This study explores the regional uptake and cellular targets of 68Ga-PSMA and 18F-DCFPyL in three different r
Externí odkaz:
https://doaj.org/article/ae43ee80bc9c463499fe50eb71a840c0
Autor:
Antje Willuweit, Michael Schöneck, Sarah Schemmert, Philipp Lohmann, Saskia Bremen, Dominik Honold, Nicole Burda, Nan Jiang, Simone Beer, Johannes Ermert, Dieter Willbold, N. Jon Shah, Karl-Josef Langen
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is characterized by formation of amyloid plaques and neurofibrillary tangles in the brain, which can be mimicked by transgenic mouse models. Here, we report on the characterization of amyloid load in the brains of two trans
Externí odkaz:
https://doaj.org/article/51186c5f2d9b4530b8dde522890f16fe
Autor:
Jörg Mauler, Alexander Heinzel, Andreas Matusch, Hans Herzog, Irene Neuner, Jürgen Scheins, Christine Wyss, Jürgen Dammers, Markus Lang, Johannes Ermert, Bernd Neumaier, Karl-Josef Langen, N. Jon Shah
Publikováno v:
NeuroImage, Vol 221, Iss , Pp 117160- (2020)
The use of hybrid PET/MR imaging facilitates the simultaneous investigation of challenge-related changes in ligand binding to neuroreceptors using PET, while concurrently measuring neuroactivation or blood flow with MRI. Having attained a steady stat
Externí odkaz:
https://doaj.org/article/c5580f460ba94f2c95ef745aff796eab
Autor:
Xuan He, Franziska Wedekind, Tina Kroll, Angela Oskamp, Simone Beer, Alexander Drzezga, Johannes Ermert, Bernd Neumaier, Andreas Bauer, David Elmenhorst
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
PurposeIn vivo imaging for the A1 adenosine receptors (A1ARs) with positron emission tomography (PET) using 8-cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxan- thine ([18F]CPFPX) has become an important tool for studying physiological processes quanti
Externí odkaz:
https://doaj.org/article/b84e31c0ec174ee7b0f089c221d3c2d4
Publikováno v:
Molecules, Vol 20, Iss 1, Pp 470-486 (2014)
Substituted phenylpiperazines are often neuropharmacologically active compounds and in many cases are essential pharmacophores of neuroligands for different receptors such as D2-like dopaminergic, serotoninergic and other receptors. Nucleophilic, no-
Externí odkaz:
https://doaj.org/article/126640cd34de49569df08967981a4abc
Autor:
Christian Filß, Felix M. Mottaghy, Heinz H. Coenen, Philipp Lohmann, Carina Stegmayr, Karl-Josef Langen, Alexander Heinzel, Gabriele Stoffels, Antje Willuweit, Johannes Ermert, Norbert Galldiks
Publikováno v:
Nuclear medicine and biology 92, 78-84 (2021). doi:10.1016/j.nucmedbio.2020.02.006
The diagnostic potential of PET using the amino acid analogue O-(2-[F-18]fluoroethyl)-L-tyrosine ([F-18]FET) in brain tumor diagnostics has been proven in many studies during the last two decades and is still the subject of multiple studies every yea
Publikováno v:
Nuclear medicine and biology 92, 43-52 (2021). doi:10.1016/j.nucmedbio.2020.07.004
Introduction The dopamine D4 receptor (D4R) has attracted considerable attention as potential target for the treatment of a broad range of central nervous system disorders. Although many efforts have been made to improve the performance of putative r