Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Johannes, Berg"'
Autor:
Robin Christensen, Lars Erik Kristensen, Daniel Furst, Torkell Ellingsen, Sabrina Mai Nielsen, Simon Tarp, Esben Malm, Johannes Berg, John P. A. Ioannidis, Josef S. Smolen, Peter C. Taylor
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Introduction Inflammatory arthritis (IA) conditions, including rheumatoid arthritis, psoriatic arthritis and axial spondyloarthritis, are characterised by inflammatory infiltration of the joints. Biological disease-modifying antirheumatic drugs (bDMA
Externí odkaz:
https://doaj.org/article/9196ff20813c4eef86045066de5c80ca
Autor:
Armita Nourmohammad, Joachim Rambeau, Torsten Held, Viera Kovacova, Johannes Berg, Michael Lässig
Publikováno v:
Cell Reports, Vol 20, Iss 6, Pp 1385-1395 (2017)
Gene expression levels are important quantitative traits that link genotypes to molecular functions and fitness. In Drosophila, population-genetic studies have revealed substantial adaptive evolution at the genomic level, but the evolutionary modes o
Externí odkaz:
https://doaj.org/article/008a574deca44c6f8f29f15e3f85568d
Autor:
Martin L. Sos, Roman K. Thomas, Jürgen Wolf, Reinhard Buettner, Martin Peifer, William Pao, Johannes Berg, Lukas C. Heukamp, Sascha Ansén, Peter Nuernberg, Johannes M. Heuckmann, Alexandra Florin, Christian Müller, Hongbin Ji, Janine Altmüller, Christian Becker, Carina Heydt, Helen Pasternack, Michaela A. Ihle, Jana Fassunke, Hans-Ulrich Schildhaus, Katharina König, Kerstin Albus, Rieke Fischer, Sebastian Michels, Marc Bos, Sabine Merkelbach-Bruse, Thorsten Persigehl, Christine M. Lovly, Lydia Meder, Lynnette Fernandez-Cuesta, Andreas H. Scheel, llona Dahmen, Dennis Plenker, Matthias Scheffler, Sandra Ortiz-Cuaran
Concomitant inhibition of MEK and EGFR is synergistic in PC9KRAS-G12S and HCC827KRAS-G12S cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b61377c2454362cbbfe49a2f4a2410
https://doi.org/10.1158/1078-0432.22460892.v1
https://doi.org/10.1158/1078-0432.22460892.v1
Autor:
Martin L. Sos, Roman K. Thomas, Jürgen Wolf, Reinhard Buettner, Martin Peifer, William Pao, Johannes Berg, Lukas C. Heukamp, Sascha Ansén, Peter Nuernberg, Johannes M. Heuckmann, Alexandra Florin, Christian Müller, Hongbin Ji, Janine Altmüller, Christian Becker, Carina Heydt, Helen Pasternack, Michaela A. Ihle, Jana Fassunke, Hans-Ulrich Schildhaus, Katharina König, Kerstin Albus, Rieke Fischer, Sebastian Michels, Marc Bos, Sabine Merkelbach-Bruse, Thorsten Persigehl, Christine M. Lovly, Lydia Meder, Lynnette Fernandez-Cuesta, Andreas H. Scheel, llona Dahmen, Dennis Plenker, Matthias Scheffler, Sandra Ortiz-Cuaran
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83ce9cf1e2f74d9d238de9825be4cb3
https://doi.org/10.1158/1078-0432.22460907.v1
https://doi.org/10.1158/1078-0432.22460907.v1
Autor:
Martin L. Sos, Roman K. Thomas, Jürgen Wolf, Reinhard Buettner, Martin Peifer, William Pao, Johannes Berg, Lukas C. Heukamp, Sascha Ansén, Peter Nuernberg, Johannes M. Heuckmann, Alexandra Florin, Christian Müller, Hongbin Ji, Janine Altmüller, Christian Becker, Carina Heydt, Helen Pasternack, Michaela A. Ihle, Jana Fassunke, Hans-Ulrich Schildhaus, Katharina König, Kerstin Albus, Rieke Fischer, Sebastian Michels, Marc Bos, Sabine Merkelbach-Bruse, Thorsten Persigehl, Christine M. Lovly, Lydia Meder, Lynnette Fernandez-Cuesta, Andreas H. Scheel, llona Dahmen, Dennis Plenker, Matthias Scheffler, Sandra Ortiz-Cuaran
Activation of ERBB2 or MET leads to decreased sensitivity to AZD9291 and rociletinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2dd86286d7696bf9b7afa255459cd3
https://doi.org/10.1158/1078-0432.22460904
https://doi.org/10.1158/1078-0432.22460904
Autor:
Martin L. Sos, Roman K. Thomas, Jürgen Wolf, Reinhard Buettner, Martin Peifer, William Pao, Johannes Berg, Lukas C. Heukamp, Sascha Ansén, Peter Nuernberg, Johannes M. Heuckmann, Alexandra Florin, Christian Müller, Hongbin Ji, Janine Altmüller, Christian Becker, Carina Heydt, Helen Pasternack, Michaela A. Ihle, Jana Fassunke, Hans-Ulrich Schildhaus, Katharina König, Kerstin Albus, Rieke Fischer, Sebastian Michels, Marc Bos, Sabine Merkelbach-Bruse, Thorsten Persigehl, Christine M. Lovly, Lydia Meder, Lynnette Fernandez-Cuesta, Andreas H. Scheel, llona Dahmen, Dennis Plenker, Matthias Scheffler, Sandra Ortiz-Cuaran
Purpose: To identify novel mechanisms of resistance to third-generation EGFR inhibitors in patients with lung adenocarcinoma that progressed under therapy with either AZD9291 or rociletinib (CO-1686).Experimental Design: We analyzed tumor biopsies fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e662a6890eec82b0f8c48767ccf2e60
https://doi.org/10.1158/1078-0432.c.6524634
https://doi.org/10.1158/1078-0432.c.6524634
Autor:
Martin L. Sos, Roman K. Thomas, Jürgen Wolf, Reinhard Buettner, Martin Peifer, William Pao, Johannes Berg, Lukas C. Heukamp, Sascha Ansén, Peter Nuernberg, Johannes M. Heuckmann, Alexandra Florin, Christian Müller, Hongbin Ji, Janine Altmüller, Christian Becker, Carina Heydt, Helen Pasternack, Michaela A. Ihle, Jana Fassunke, Hans-Ulrich Schildhaus, Katharina König, Kerstin Albus, Rieke Fischer, Sebastian Michels, Marc Bos, Sabine Merkelbach-Bruse, Thorsten Persigehl, Christine M. Lovly, Lydia Meder, Lynnette Fernandez-Cuesta, Andreas H. Scheel, llona Dahmen, Dennis Plenker, Matthias Scheffler, Sandra Ortiz-Cuaran
Targeted and Sanger sequencing results at the EGFR locus for P6 and P7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e81b48ee2be8da8f7783d22fac8ebd1
https://doi.org/10.1158/1078-0432.22460901
https://doi.org/10.1158/1078-0432.22460901
Autor:
Martin L. Sos, Roman K. Thomas, Jürgen Wolf, Reinhard Buettner, Martin Peifer, William Pao, Johannes Berg, Lukas C. Heukamp, Sascha Ansén, Peter Nuernberg, Johannes M. Heuckmann, Alexandra Florin, Christian Müller, Hongbin Ji, Janine Altmüller, Christian Becker, Carina Heydt, Helen Pasternack, Michaela A. Ihle, Jana Fassunke, Hans-Ulrich Schildhaus, Katharina König, Kerstin Albus, Rieke Fischer, Sebastian Michels, Marc Bos, Sabine Merkelbach-Bruse, Thorsten Persigehl, Christine M. Lovly, Lydia Meder, Lynnette Fernandez-Cuesta, Andreas H. Scheel, llona Dahmen, Dennis Plenker, Matthias Scheffler, Sandra Ortiz-Cuaran
Expression of KRASG12S mutant results in decreased sensitivity to AZD9291 and rociletinib in EGFR mutated cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fa083fd2bc5cdd84d177fcf5a3f75e3
https://doi.org/10.1158/1078-0432.22460898.v1
https://doi.org/10.1158/1078-0432.22460898.v1
Publikováno v:
Biophysical Journal, 121(2), 183-192. CELL PRESS
Biophys J
Biophys J
The lactose uptake-pathway of E. coli is a paradigmatic example of multistability in gene-regulatory circuits. In the induced state of the lac-pathway, the genes comprising the lac-operon are transcribed, leading to the production of proteins which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e33290e65d5b8115c4db6833676553d
https://hdl.handle.net/11370/58cc506c-3562-4a80-b1aa-953c14f23979
https://hdl.handle.net/11370/58cc506c-3562-4a80-b1aa-953c14f23979