Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Johanne M Pentier"'
Autor:
Andrew B Gerry, Bent K Jakobsen, David Krige, Rahul C Khanolkar, James A Davies, Alexander T Baker, Thomas A Webb, Alicia Teijeira-Crespo, Hanni K Uusi-Kerttula, Lucy M Williams, Samantha L Moore, Johanne M Pentier, Alan L Parker, David K Cole
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/9e3c849f17ae4098a4e02487851dbaa0
Autor:
Malkit Sami, Ben de Wet, Elizabeth A. Potter, Rory M. Crean, Katy A. Lloyd, Velupillai Srikannathasan, Nikolai Lissin, Milos Aleksic, Anitha Jeyanthan, Miriam Hock, David K. Cole, Peter Eamon Molloy, Pierre J. Rizkallah, Marco Lepore, Annelise Vuidepot, Christopher J. Holland, Brian Cameron, Thomas Blicher, Robert J. Pengelly, Christopher R. Pudney, Ross A. Robinson, Johanne M. Pentier, Thomas E. Spinner, Marc W. van der Kamp, Bent K. Jakobsen, Nathaniel Liddy, Paul J. Conroy, Stephen Harper, Angharad Lloyd
Publikováno v:
J Clin Invest
Tumor-associated peptide-human leukocyte antigen complexes (pHLAs) represent the largest pool of cell surface-expressed cancer-specific epitopes, making them attractive targets for cancer therapies. Soluble bispecific molecules that incorporate an an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbe9e3e9f83c5de1920113bed8d5316
https://europepmc.org/articles/PMC7190993/
https://europepmc.org/articles/PMC7190993/
Autor:
Andrea J. A. Schauenburg, David Price, David K. Cole, John J. Miles, Johanne M. Pentier, Andrew Trimby, Julia Ekeruche-Makinde, Hugo A. van den Berg, Ania Skowera, Mai Ping Tan, Jamie Rossjohn, Garry Dolton, Anna Marta Bulek, Tamsin Williams, Andrew K. Sewell, Kim M. Miles, Sian Llewellyn-Lacey, Mick Bailey, Linda Wooldridge, Mathew Clement, Pierre J. Rizkallah, Scott R. Burrows, Mark Peakman
Publikováno v:
Blood. 121:1112-1123
αβ-TCRs expressed at the CD8(+) T-cell surface interact with short peptide fragments (p) bound to MHC class I molecules (pMHCI). The TCR/pMHCI interaction is pivotal in all aspects of CD8(+) T-cell immunity. However, the rules that govern the outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d0f45966e93cb14ef7416cdd998570
https://doi.org/10.1182/blood-2012-06-437202
https://doi.org/10.1182/blood-2012-06-437202
Autor:
David Price, Johanne M. Pentier, Julia Ekeruche-Makinde, Emma Gostick, Linda Wooldridge, Florian Madura, John J. Miles, Mathew Clement, Katherine K. Matthews, Kristin Ladell, Katy A. Lloyd, Andrew K. Sewell, David K. Cole, Garry Dolton, Brian M. Baker, Tiffany K. Baxter, Anna Lissina, Emily S.J. Edwards, Anna Fuller, Pierre J. Rizkallah
Publikováno v:
The Journal of Biological Chemistry
Background: Current peptide vaccines may select suboptimal antigen-specific T-cells from polyclonal populations. Results: A combinatorial peptide library screen was used to generate an optimal ligand that could preferentially activate a known effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db9b579a4f57dd023b3052018435df0
https://doi.org/10.1074/jbc.m112.386409
https://doi.org/10.1074/jbc.m112.386409
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology
Frontiers in Immunology
T-cells recognize small peptide fragments (p) cradled in multiple major histocompatibility complex (MHC) molecules, termed human leukocyte antigens (HLA) in humans. These membrane-integral pMHC molecules are present on surface of all nucleated cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97622cfe092de2057528a0588e17ddc
https://doi.org/10.3389/fimmu.2013.00133
https://doi.org/10.3389/fimmu.2013.00133
Autor:
Luise U. Weigand, Johanne M. Pentier, Martina Canestraro, Mary Connolly, Bent K. Jakobsen, Ruth Ryan, Annelise Vuidepot, Namir J. Hassan
Publikováno v:
Cancer Immunology Research. 4:A037-A037
For years cancer therapies were mainly concentrated around surgery, chemotherapy and radiotherapy. Recently, a new domain has emerged. Immunotherapies aim to exploit, enhance and optimise the patient's immune system to be more potent at eradicating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::346246e98175e287e9fbcde6430ba6cf
https://doi.org/10.1158/2326-6074.cricimteatiaacr15-a037
https://doi.org/10.1158/2326-6074.cricimteatiaacr15-a037