Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Johanne M Murray"'
Autor:
Thomas J Etheridge, Desiree Villahermosa, Eduard Campillo-Funollet, Alex David Herbert, Anja Irmisch, Adam T Watson, Hung Q Dang, Mark A Osborne, Antony W Oliver, Antony M Carr, Johanne M Murray
Publikováno v:
eLife, Vol 10 (2021)
The essential Smc5/6 complex is required in response to replication stress and is best known for ensuring the fidelity of homologous recombination. Using single-molecule tracking in live fission yeast to investigate Smc5/6 chromatin association, we s
Externí odkaz:
https://doaj.org/article/a87f3e7fa1b34575930f08ff8d91c899
Autor:
Hossain Mohammad Shamim, Yukako Minami, Daiki Tanaka, Shinobu Ukimori, Johanne M Murray, Masaru Ueno
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187775 (2017)
Thymidine kinase converts 5-fluorodeoxyuridine to 5-fluorodeoxyuridine monophosphate, which causes disruption of deoxynucleotide triphosphate ratios. The fission yeast Schizosaccharomyces pombe does not express endogenous thymidine kinase but 5-fluor
Externí odkaz:
https://doaj.org/article/cacdc72e7f3f498c96e62858d6fdebea
Autor:
Adam T Watson, Yasukazu Daigaku, Saed Mohebi, Thomas J Etheridge, Charly Chahwan, Johanne M Murray, Antony M Carr
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83800 (2013)
The ability to study protein function in vivo often relies on systems that regulate the presence and absence of the protein of interest. Two limitations for previously described transcriptional control systems that are used to regulate protein expres
Externí odkaz:
https://doaj.org/article/2c2ce5bd80bc475f8bbc1028d5e18c78
Publikováno v:
Cells, Vol 13, Iss 10, p 812 (2024)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/a1d25c6906144eab87e48379f23b7788
Autor:
Chen-Chun Pai, Samuel C Durley, Wei-Chen Cheng, Nien-Yi Chiang, Jennifer Peters, Torben Kasparek, Elizabeth Blaikley, Boon-Yu Wee, Carol Walker, Stephen E Kearsey, Francesca Buffa, Johanne M Murray, Timothy C Humphrey
Chromosomal instability (CIN) drives cell-to-cell heterogeneity, and the development of genetic diseases, including cancer. Impaired homologous recombination (HR) has been implicated as a major driver of CIN, however, the underlying mechanism remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430e423c224ed90a7ebfeba2d915668a
https://doi.org/10.1093/nar/gkad160
https://doi.org/10.1093/nar/gkad160
Autor:
Stephen T Hallett, Isabella Campbell Harry, Pascale Schellenberger, Lihong Zhou, Nora B Cronin, Jonathan Baxter, Thomas J Etheridge, Johanne M Murray, Antony W Oliver
The Smc5/6 complex plays an essential role in the resolution of recombination intermediates formed during mitosis or meiosis, or as a result of the cellular response to replication stress. It also functions as a restriction factor preventing viral re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b27298ea302aca13e173c83176adc9b
http://sro.sussex.ac.uk/id/eprint/107236/4/gkac692.pdf
http://sro.sussex.ac.uk/id/eprint/107236/4/gkac692.pdf
Publikováno v:
Cells; Volume 11; Issue 1; Pages: 165
Cells
Cells, Vol 11, Iss 165, p 165 (2022)
Cells
Cells, Vol 11, Iss 165, p 165 (2022)
Structural Maintenance of Chromosomes (SMC) complexes are important for many aspects of the chromosomal organization. Unlike cohesin and condensin, the SMC5/6 complex contains a variant RING domain carried by its Nse1 subunit. RING domains are charac
Autor:
Lydia Hulme, John Prudden, Carol Walker, Timothy C. Humphrey, Samuel C. Durley, Adam T. Watson, Helen Tinline-Purvis, Boon-Yu Wee, Johanne M. Murray, Anoushka Davé, Chen-Chun Pai, Jason K Cullen, Antony M. Carr, Sovan Sarkar
Publikováno v:
Nucleic Acids Research
The healing of broken chromosomes by de novo telomere addition, while a normal developmental process in some organisms, has the potential to cause extensive loss of heterozygosity, genetic disease, or cell death. However, it is unclear how de novo te
Autor:
Jonathan Baxter, Thomas J. Etheridge, Pascale Schellenberger, Johanne M. Murray, Lihong Zhou, Isabella Campbell Harry, Nora B. Cronin, Antony W. Oliver, Stephen T Hallett
The Smc5/6 complex plays an essential role in the resolution of recombination intermediates formed during mitosis or meiosis, or as a result of the cellular response to replication stress. It also functions as a restriction factor preventing viral re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bad974a4a650593ca1c3ff953a50646
https://doi.org/10.1101/2021.11.25.470006
https://doi.org/10.1101/2021.11.25.470006
Autor:
Rui Yan, Yue Yuan, Daochun Kong, Lu Wang, Yuchen Xie, Zeqi Zheng, Antony M. Carr, Bo Zhang, Zeyang Li, Xin Xu, Jianguo Ji, Yang Liu, Johanne M. Murray
Publikováno v:
Proc Natl Acad Sci U S A
Significance The intra-S phase checkpoint is essential to stabilize stalling/stalled replication forks. However, the mechanism underlying checkpoint regulation is poorly understood; two key questions remain to be answered: 1) why are stalling forks u