Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Johanne Lauritsen"'
Autor:
Janni Nielsen, Johanne Lauritsen, Jannik N. Pedersen, Jan S. Nowak, Malthe K. Bendtsen, Giulia Kleijwegt, Kaija Lusser, Laia C. Pitarch, Julián V. Moreno, Matthias M. Schneider, Georg Krainer, Louise Goksøyr, Paul Khalifé, Sanne Simone Kaalund, Susana Aznar, Magnus Kjærgaard, Vita Sereikaité, Kristian Strømgaard, Tuomas P. J. Knowles, Morten Agertoug Nielsen, Adam F. Sander, Marina Romero-Ramos, Daniel E. Otzen
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-26 (2024)
Abstract α-Synuclein (α-syn) accumulates as insoluble amyloid but also forms soluble α-syn oligomers (αSOs), thought to be even more cytotoxic than fibrils. To detect and block the unwanted activities of these αSOs, we have raised 30 monoclonal
Externí odkaz:
https://doaj.org/article/e6e9d9eb66fb4db88fab4f91ceef8060
Autor:
Muyesier Maimaitili, Muwan Chen, Fabia Febbraro, Ekin Ucuncu, Rachel Kelly, Jonathan Christos Niclis, Josefine Rågård Christiansen, Noëmie Mermet-Joret, Dragos Niculescu, Johanne Lauritsen, Angelo Iannielli, Ida H. Klæstrup, Uffe Birk Jensen, Per Qvist, Sadegh Nabavi, Vania Broccoli, Anders Nykjær, Marina Romero-Ramos, Mark Denham
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Current differentiation protocols for generating mesencephalic dopaminergic (mesDA) neurons from human pluripotent stem cells result in grafts containing only a small proportion of mesDA neurons when transplanted in vivo. In this study, we d
Externí odkaz:
https://doaj.org/article/cabafdbe91e44ff087afd66e98f70397
Autor:
Miriam Højholt Terkelsen, Ida H. Klaestrup, Victor Hvingelby, Johanne Lauritsen, Nicola Pavese, Marina Romero-Ramos
Publikováno v:
Terkelsen, M H, Klæstrup, I H, Hvingelby, V, Lauritsen, J, Pavese, N & Romero-Ramos, M 2022, ' Neuroinflammation and Immune Changes in Prodromal Parkinson’s Disease and Other Synucleinopathies ', Journal of Parkinson's Disease, vol. 12, no. s1, pp. S149-S163 . https://doi.org/10.3233/JPD-223245
Multiple lines of clinical and pre-clinical research support a pathogenic role for neuroinflammation and peripheral immune system dysfunction in Parkinson’s disease. In this paper, we have reviewed and summarised the published literature reporting