Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Johanne Lade-Keller"'
Autor:
Siri Nana Halling Svensgaard, Pikka Jokelainen, Christen Rune Stensvold, Karen Rokkedal Lausch, Anette Højsgaard, Johanne Lade Keller, Henrik Vedel Nielsen, Carsten Schade Larsen
Publikováno v:
IDCases, Vol 33, Iss , Pp e01833- (2023)
Background: Cystic echinococcosis is non-endemic in Denmark and primarily diagnosed in migrants from endemic areas. Here, we report a case of pulmonary cystic echinococcosis in a Danish woman with no history of longer-term stays abroad, only holiday
Externí odkaz:
https://doaj.org/article/ab130e3a2a124e82942b62342846ea5c
Autor:
Trine V. Larsen, Nina Dybdal, Tina F. Daugaard, Johanne Lade-Keller, Lin Lin, Boe S. Sorensen, Anders L. Nielsen
Publikováno v:
Larsen, T V, Dybdal, N, Daugaard, T F, Lade-Keller, J, Lin, L, Sorensen, B S & Nielsen, A L 2023, ' Examination of the Functional Relationship between PD-L1 DNA Methylation and mRNA Expression in Non-Small-Cell Lung Cancer. ', Cancers, vol. 15, no. 6, 1909 . https://doi.org/10.3390/cancers15061909
Cancers; Volume 15; Issue 6; Pages: 1909
Cancers; Volume 15; Issue 6; Pages: 1909
Immunotherapy targeting the interaction between programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) is a treatment option for patients with non-small-cell lung cancer (NSCLC). The expression of PD-L1 by the NSCLC cells determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b370ac790859bb6475adc9ae09352da7
https://pure.au.dk/portal/da/publications/examination-of-the-functional-relationship-between-pdl1-dna-methylation-and-mrna-expression-in-nonsmallcell-lung-cancer(8013c398-2eac-43cc-a4d5-048afc28fd16).html
https://pure.au.dk/portal/da/publications/examination-of-the-functional-relationship-between-pdl1-dna-methylation-and-mrna-expression-in-nonsmallcell-lung-cancer(8013c398-2eac-43cc-a4d5-048afc28fd16).html
Autor:
Carina Mellemgaard, Ib Jarle Christensen, Giedrius Salkus, Pia Wirenfeldt Staun, Niels Korsgaard, Kim Hein Lindahl, Mathilde Skaarup Larsen, Siri Klausen, Johanne Lade-Keller
Publikováno v:
Mellemgaard, C, Christensen, I J, Salkus, G, Wirenfeldt Staun, P, Korsgaard, N, Hein Lindahl, K, Skaarup Larsen, M, Klausen, S & Lade-Keller, J 2023, ' Reducing workload in malignant melanoma sentinel node examination : a national study of pathology reports from 507 melanoma patients ', Journal of Clinical Pathology . https://doi.org/10.1136/jcp-2022-208743
AimsEven though extensive melanoma sentinel node (SN) pathology protocols increase metastasis detection, there is a need for balancing high detection rates with reasonable workload. A newly tested Danish protocol recommended examining nodes at six le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86120f03dd24d8439f8621942e250ec2
https://vbn.aau.dk/da/publications/f0eafa2c-30cc-4d2d-a9d2-265198c3591e
https://vbn.aau.dk/da/publications/f0eafa2c-30cc-4d2d-a9d2-265198c3591e
Publikováno v:
Journal of clinical pathology.
The aim of this study was to investigate the association between oncogenic alterations and programmed cell death ligand 1 (PD-L1) expression in lung adenocarcinomas, as well as the prognostic value ofThis study is a retrospective cohort study of 519
Autor:
Lisa Loksø Dietz, Natasja Toft Furman, Trine Vilsbøll Larsen, Tina Fuglsang Daugaard, Emil Aagaard Thomsen, Johanne Lade Keller, Lars Aagaard, Boe Sandahl Sorensen, Anders Lade Nielsen
Publikováno v:
Dietz, L L, Furman, N T, Larsen, T V, Daugaard, T F, Thomsen, E A, Keller, J L, Aagaard, L, Sorensen, B S & Nielsen, A L 2022, ' An Extended PD-L2 Cytoplasmic Domain Results From Alternative Splicing in NSCLC Cells ', Journal of Immunotherapy, vol. 45, no. 9, pp. 379-388 . https://doi.org/10.1097/CJI.0000000000000439
Antibody-based immunotherapy targeting the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 has shown impressive clinical outcomes in various cancer types, including nonsmall cell lung cancer (NSCLC). However, regulatory mechan
Publikováno v:
Journal of Clinical Pathology. :jcp-2022
AimsThe aim of this study was to investigate the association between oncogenic alterations and programmed cell death ligand 1 (PD-L1) expression in lung adenocarcinomas, as well as the prognostic value ofKRASand/orTP53mutations in patients treated wi
Autor:
Anita Tranberg Simonsen, Amalie Utke, Johanne Lade-Keller, Lasse Westphal Thomsen, Torben Steiniche, Magnus Stougaard
Publikováno v:
Simonsen, A T, Utke, A, Lade-Keller, J, Thomsen, L W, Steiniche, T & Stougaard, M 2022, ' A targeted expression panel for classification, gene fusion detection and PD-L1 measurements – Can molecular profiling replace immunohistochemistry in non-small cell lung cancer? ', Experimental and Molecular Pathology, vol. 125, 104749 . https://doi.org/10.1016/j.yexmp.2022.104749
The histological classification of non-small-cell lung cancer (NSCLC) and identification of possible therapeutic targets are important for disease management. However, as biopsies are often small, with a limited amount of tumor cells, it can be chall
Publikováno v:
Tønnesen, E, Lade-Keller, J & Stougaard, M 2021, ' Frequently used quantitative polymerase chain reaction–based methods overlook potential clinically relevant genetic alterations in epidermal growth factor receptor compared with next-generation sequencing : a retrospective clinical comparison of 1839 lung adenocarcinomas ', Human Pathology, vol. 115, pp. 67-75 . https://doi.org/10.1016/j.humpath.2021.06.001
Summary Aims The aim of the study was to investigate the advantage of implementing next-generation sequencing (NGS) compared with quantitative polymerase chain reaction (qPCR) when performing routine molecular diagnostics in adenocarcinomas of the lu
Publikováno v:
Özcan, D, Lade-Keller, J & Tramm, T 2021, ' Can evaluation of mismatch repair defect and TILs increase the number of triple-negative breast cancer patients eligible for immunotherapy? ', Pathology Research and Practice, vol. 226, 153606 . https://doi.org/10.1016/j.prp.2021.153606
Background Programmed-cell-death-ligand 1 (PD-L1) inhibitor treatment is approved for metastatic/recurrent, PD-L1 positive, triple-negative breast cancer (TNBC) and solid tumors with mismatch repair (MMR) defect regardless of PD-L1 status. The analyt
Publikováno v:
Lade-Keller, J, Yuusufi, S, Riber-Hansen, R, Steiniche, T & Stougaard, M 2018, ' Telomerase reverse transcriptase promoter mutations and solar elastosis in cutaneous melanoma ', Melanoma Research, vol. 28, no. 5, pp. 398-409 . https://doi.org/10.1097/CMR.0000000000000446
The aims of this study were to assess the prognostic potential of solar elastosis grading and telomerase reverse transcriptase (TERT) promoter mutations (TERTp) in melanoma and to evaluate whether an association between solar elastosis and TERTp exis